God,this is insane.I—a 21st-century Chinese kid—have been reincarnated into the Kingdom of France under the Bourbon dynasty.But here’s the realkicker:I’m the Crown Prince of France.The catch?The king right now is Louis XVI…and in just a few years,he’ll be guillotined.Surrounded by 18th-century French nobles who speak a language I barely grasp,dressed in silk and powdered wigs while my mind races with 2025 tech,memes,and modern ideals…I’m like an alien dropped into their cou...

Reborn and transported to a world akin to Dungeons & Dragons, a boy grows step-by-step into a legendary sorcerer—only to find himself entangled in a forbidden love for his own sister. This is no mere adventure: it’s a mortal’s defiance of deities, a journey from pawn to player on a cosmic chessboard. It’s the story of a Netherese scion reclaiming his fallen empire’s glory, set in the iconic Forgotten Realms. At its heart, it’s a tale of fate, conspiracy, love, and—well, justice… or rather,...

Drug development is at a crossroads. As personalized medicine and targeted therapies expand, traditional clinical trial models have become too slow, costly, and inefficient. To meet the urgent need for faster, reliable evidence generation and decision making, researchers and regulators alike have turned to innovative trial designs. Among these, master protocols stand out as a transformative approach, allowing multiple therapies, disease subtypes, or objectives to be studied under a single,...

Active colloids are self-propelled particles, powered by energy harvested from the environment. This field of research has been growing over the past 20 years, attracting researchers from multiple disciplines. Biomedical engineers seek to harness the abilities of motile bacteria, materials chemists are fascinated by the concept of synthetic particles becoming autonomous and the new opportunities this presents, and soft matter physicists see active colloids as a model system for active matt...

Robotic spine surgery is one of the fastest growing segments of the spine surgery market. Surgeons specialising in spine surgery are highly motivated to learn and improve their understanding of the indications,application,and future clinical scope of using new technological platforms. Spinal surgeons face time pressures but are hungry for new ways to effectively treat patients. This book presents information in the case study format. By using examples of surgical cases of an advanced natur...

The Oxford Handbook of Chinese Linguistics offers a broad and comprehensive coverage of the entire field from a multi-disciplinary perspective. All chapters are contributed by leading scholars in their respective areas. This Handbook contains eight sections: history, languages and dialects, language contact, morphology, syntax, phonetics and phonology, socio-cultural aspects and neuro-psychological aspects. It provides not only a diachronic view of how languages evolve, b...

Quantitative Methodologies and Process for Safety Monitoring and Ongoing Benefit Risk Evaluation provides a comprehensive coverage on safety monitoring methodologies, covering both global trends and regional initiatives. Pharmacovigilance has traditionally focused on the handling of individual adverse event reports however recently there had been a shift towards aggregate analysis to better understand the scope of product risks.Written to be accessible not...

Global simultaneous development is becoming more necessary as the cost of developing medical products continues to grow. The strategy of using multiregional clinical trials (MRCTs) has become the preferred method for developing new medicines. Implementing the same protocol to include subjects from many geographical regions around the world, MRCTs can speed up the patient enrolment, thus resulting in quicker drug development and obtaining faster approval of the drug globally.After t...

Our cities, and the systems that support them, have not been designed to address the FWE nexus. There exist gaps in awareness of the role and impacts of climate change. Improving communication among stakeholders with the support of scientific evidence is the key to narrowing the gaps. This book approached this issue with a multidisciplinary and transdisciplinary moveable nexus approach through the lens of FEW nexus under the project of the Sustainable Urbanization Global Initiative of Belm...

Lipidomics is one of the emerging ‘omics’ techniques with growing importance in bioscience. Discussing interesting standard and non-standard techniques relevant to the measurement and analysis of lipids by mass spectrometry, this book will provide a guide to the possibilities of the techniques. It will introduce the reader to exciting new methods that allow isomer differentiation, improve sensitivity, allow spatial location and go beyond annotation of simply matching a mass to a database e...

Handbook of Developmental Neurotoxicology, Second Edition, provides a comprehensive view of the fundamental aspects of neurodevelopment, the pathways and agents that affect them, relevant clinical syndromes, and risk assessment procedures for developmental neurotoxicants. The editors and chapter authors are internationally recognized experts whose collaboration heralds a remarkable advance in the field, bridging developmental neuroscience with the principles of neurotoxicology. The book fe...

This book describes how systems biology, pharmacogenomic and behavioral approaches, as applied to neurodevelopmental toxicology, provide a structure to arrange information in a biological model. Authors review and discuss approaches that can be used as effective tools to dissect mechanisms underlying pharmacological and toxicological phenomena associated with the exposure to drugs or environmental toxicants during development. This book presents cross-cutting research tools and animal mode...