The book provides a description of the process of health economic evaluation and modelling for cost-effectiveness analysis, particularly from the perspective of a Bayesian statistical approach. Some relevant theory and introductory concepts are presented using practical examples and two running case studies. The book also describes in detail how to perform health economic evaluations using the R package BCEA (Bayesian Cost-Effectiveness Analysis). BCEA can be used to post-process the resul...

La comédie romantique par John Green !Dix-neuf fois Colin est tombé amoureux.Dix-neuf fois la fille s'appelait Katherine.Pas Katie, ni Kat, ni Kittie, ni Cathy, et surtout pas Catherine, mais KATHERINE.Et dix-neuf fois, il s'est fait larguer.

Hazel, 16 ans, est atteinte d'un cancer. Son dernier traitement semble avoir arrêté l'évolution de la maladie, mais elle se sait condamnée. Bien qu'elle s'y ennuie passablement, elle intègre un groupe de soutien, fréquenté par d'autres jeunes malades. C'est là qu'elle rencontre Augustus, un garçon en rémission, qui partage son humour et son goût de la littérature. Entre les deux adolescents, l'attirance est immédiate. Et malgré les réticences d'Hazel, qui a peur de s'impliquer dans une rel...

Un roman sous forme de journal très illustré, à lire progressivement en anglaisJ'ai décidé d'écrire un journal en anglais. Ma motivation : Akira, mon amie écossaise ! Akirais funny, nice, intelligent, Scottish... Je ne savais pas encore qu'un projet avec mon prof de biologie allait m'amener à faire une étonnante découverte. Et que j'allais aussitôt avoir besoin d'Akira... Because Akira's brother studies ecology at university!Niveau " Je découvre l'anglais " - A1 Décou...

Et si la nouvelle génération changeait le monde ?Marie enquête cette fois-ci en Amazonie.Marie part au Brésil enquêter sur la déforestation amazonienne.Sur place, elle fait la rencontre de Joaquin, fils de riches propriétaires terriens,dont elle tombe amoureuse.Andrea et LO font des recherches de leur côté et tombent sur une source anonymequi leur fournit des documents démontrant les agissements illégaux de certai...

In The Black Veil, Jack the Ripper terrorizes Victorian London with ritualistic killings that are linked to ancient magical artifacts. Blind occultist Miranda Griffin is plunged into a chilling mystery that blends history, literature, and the horror found in the arcane myths of Britain. Made invisible by a cursed ancient relic, Miranda steps into the darkness to uncover the truth behind the legendary Thirteen Treasures: objects that wield terrible power. Those who seek them leave bloody tr...

"An Altar on the Village Green enthralled me from the start. This is an amazing debut . . . one of my favorite reads this year."- Clayton W Snyder"If one suffers, I suffer. If one is chained, I am chained."My faith called me to become a Lance. My compassion drew me into one of the fallen lands. Through my connection with the Chained God, I alone can find and destroy the Horror that stains the land.Death can no longer chain me.But I couldn't have imag...

This is a book combo with the following titles in it:Book 1: When doing taxes, accounting, or income statements, many people are puzzled. It starts with knowing what is what: the definitions. Then, filling out the balance sheets and the numbers, can be an equally complicated task as well. And finally, most people want to get the most out of their business or salary: The highest return, the lowest costs, and the lowest amount of taxes paid.Book 2: In this guide, you will lea...

This is a book combo with the following titles in it:Book 1: When doing taxes, accounting, or income statements, many people are puzzled. It starts with knowing what is what: the definitions. Then, filling out the balance sheets and the numbers, can be an equally complicated task as well. And finally, most people want to get the most out of their business or salary: The highest return, the lowest costs, and the lowest amount of taxes paid.Book 2: Running a business can be a...

Un roman fin, sensible, tout en demi-teintes et en silences, sur le lien très fort entre une jeune fille et sa mère, danseuse étoile, qu'elle admire plus que tout."Il y a seulement douze étoiles à l'Opéra, six hommes et six femmes. L'une d'elles est ma mère."La mère de Laurie est danseuse étoile. Laurie ne vit que pour cette mère " à part ", à la fois fascinante et fragile, qu'elle croit de son devoir de protéger. Lorsque sa maman lui apprend qu'elle est amoureuse, Laurie p...

Julian never expected that coming home would feel heavier than leaving.After a decade chasing success in Chicago’s high pressure finance world, Julian returns to the small coastal town of Oakhaven, Maine. Burned out and uncertain of who he has become, he takes over his grandmother’s old laundry shop, The Verdant Press. What once seemed like a quiet and ordinary business slowly reveals itself to be something far more meaningful.Every item that arrives at the counter carries a story.A retire...

This is a book combo with the following titles in it:Book 1: When it comes to considering your finances, many decisions are involved. The numbers count!So, in order to understand those numbers, some terms have to be understood first. The words that are used in the financial world, can be daunting at times. But fear no longer, my good friend. Help is on the way!Book 2: A lot of business owners and managers get many things right, but there are also things they can do ...