With a focus on case studies of R&D programs in a variety of disease areas, the book highlights fundamental productivity issues the pharmaceutical industry has been facing and explores potential ways of improving research effectiveness and efficiency.Takes a comprehensive and holistic approach to the problems and potential solutions to drug compound attritionTackles a problem that adds billions of dollars to drug development programs and health care...

Closing a gap in the scientifi c literature, this first comprehensive introduction to the topic is based on current best practice in one of the largestpharmaceutical companies worldwide. The first chapters trace the development of our understanding of drug metabolite toxicity, covering basic concepts and techniques in the process, while the second part details chemical toxicophores that are prone to reactive metabolite formation. This section also reviews the various drug-metabolizi...

Christianity Today Book Award—Biblical StudiesForeword INDIES Book of the Year Award Honorable MentionSOLA Network's Asian American Book Awards Honorable MentionIn a first-of-its-kind volume, The New Testament in Color offers biblical commentary that is:MultiethnicDiverseContextual

The story of the greatest of all philosophical friendships—and how it influenced modern thoughtDavid Hume is widely regarded as the most important philosopher ever to write in English, but during his lifetime he was attacked as “the Great Infidel” for his skeptical religious views and deemed unfit to teach the young. In contrast, Adam Smith was a revered professor of moral philosophy, and is now often hailed as the founding father of capitalism. Remarkably, the two...

A Companion to African Rhetoric, edited by Segun Ige, Gilbert Motsaathebe, and Omedi Ochieng, presents the reader with different perspectives on African rhetoric mostly from Anglophone sub-Saharan Africa and the Diaspora. The African, Afro-Caribbean, and African American rhetorician contributors conceptualize African rhetoric, examine African political rhetoric, analyze African rhetoric in literature, and address the connection between rhetoric and religion in Africa. They argue for a holi...

Between 1995 and 2002, Dark Terrors: The Gollancz Book of Horror was Britain's premier non-themed anthology of original horror stories.Over six volumes, it published some of the biggest names in the field as well as many newcomers who have gone on to forge impressive careers in the genre.Edited by the World Fantasy Award-winning team of Stephen Jones and David A. Sutton, Dark Terrors established itself as a cutting-edge market for some of the most literary and disturbing fi...

"This study Bible is a must-have to help us see Jesus Christ throughout the whole Bible." —biblereviewguys.comThe ESV Gospel Transformation Study Bible is designed to help readers see Christ in all of Scripture, and grace for all of life.It features book introductions, gospel-centered study notes, and a series of all-new articles—written by a team of over 50 pastors and scholars. This content explains passage-by-passage how God's redemptive purposes culminate in th...

Pedro Gomez of ESPN was a beloved figure in baseball. His death from sudden cardiac arrest on Feb. 7, 2021, unleashed an outpouring of heartfelt tributes. He was 58, both a hard-nosed reporter and a smiling ambassador of the sport. These 62 personal essays soar beyond sports to delve into life lessons.Pedro, a proud Cuban American, was known for his dramatic reporting from Havana. Fully and fluidly bilingual, he did as much as anyone to bridge the wide gap that had...

As Appy plans to retire, he reminisces his first day of hire longing and wishing to aspire acquiring a trade while we perspire educating at schools of learning higher gathering experiences to fulfil his desire observing caterpillars morph into stages they require waiting for the butterflies as they transpire counting down the days to the wire and finally enjoying his fruitful endeavour.

Ce livre comprend 40 jours de réflexions quotidiennes visant à renforcer votre relation avec Jésus-Christ et vous encouragera à accompagner celles et ceux qui sont en recherche d'espérance.Pourquoi 40 jours ? La Bible relate plusieurs événements importants qui se sont produits pendant ce laps de temps : la pluie est tombée pendant 40 jours lors du Déluge. Moïse est resté sur le mont Sinaï avec Dieu pendant 40 jours. Les espions d'Israël ont pris 40 jours pour explorer la Terre Prom...

Studies of Communication in the 2020 Presidential Campaign explores a wide range of communication elements, themes, and topics of the 2020 presidential election. The introduction provides a brief snapshot summarizing the role of more traditional elements of campaign communication as well as the newer elements of social media and journalistic practices that transformed the political landscape in 2020. Each chapter serves as a stand-alone study focusing on the role and function of c...

Deidre-Ann is an eleventh grade student who seems to have everything going for her. She is brilliant, attractive and involved in school life and extra-curricular activities, especially cheerleading.The students consider her to be the ‘salt’ of the team. They applaud her expertise and crave her company but alas’, the salt of the earth loses her savour when her innocence and dignity are snatched from her on the night of the school barbecue. Her life spirals out of control as she beco...