This volume constitutes the refereed proceedings of the Second International Workshop on Advanced Methodologies for Bayesian Networks, AMBN 2015, held in Yokohama, Japan, in November 2015.The 18 revised full papers and 6 invited abstracts presented were carefully reviewed and selected from numerous submissions. In the International Workshop on Advanced Methodologies for Bayesian Networks (AMBN), the researchers explore methodologies for enhancing the effectiveness of graphical mode...