This volume reflects the contributions stemming from the conference Analytic and Combinatorial Number Theory: The Legacy of Ramanujan which took place at the University of Illinois at Urbana-Champaign on June 6–9, 2019. The conference included 26 plenary talks, 71 contributed talks, and 170 participants. As was the case for the conference, this book is in honor of Bruce C Berndt and in celebration of his mathematics and his 80th birthday.Along with a number of papers previously app...