Unbeknownst to remote triibal villagers living deep within the Amazon rainforest, a host of mythological creatures vie for supremacy over what remains of mankind. When finally the battle spills into their village and a young, pregnant girl bitten, she and a lone warrior must leave the only home they ever knew in order to survive.

When an Amazonian werewolf bites the mother of his unborn child, a tribesman must prove himself worthy in order to find a cure.