Maintaining a practical perspective, Bioequivalence and Statistics in Clinical Pharmacology, Second Edition explores statistics used in day-to-day clinical pharmacology work. The book is a starting point for those involved in such research and covers the methods needed to design, analyze, and interpret bioequivalence trials; explores when, how, and why these studies are performed as part of drug development; and demonstrates the methods using real world examples.

揭露量化交易大師暴賺千億美元背後的原理與秘辛，一夕之間，理智的投資數學模型可能變成投機豪賭！★《黑天鵝效應》作者塔雷伯力薦，《暗池》作者又一大作！★《紐約時報》暢銷書，《彭博社》、《商業週刊》、《金融時報》媒體好評★《亞馬遜網站》讀者4.5星強力推薦◤他們都是市場中的食人魚，嗅到價格偏差的套利機會便一擁而上吉姆‧西蒙斯：量化交易之父，旗下大獎章基金平均年化報酬率高達66.1％。愛德華．索普：稱霸賭城和華爾街的傳奇數學家，執掌PNP基金時從未虧損。彼得．穆勒：摩根史坦利神秘的PDT基金前經理，五年帶來十億美元淨收入。克里夫．艾斯尼斯：量化領域知名AQR基金創立人，長期維持雙位數報酬率。這些數學鬼才是如何賺到超越巴菲特的報酬？而他們管理的億萬資產，又為何在投機下一夕化為泡沫？◤但巴菲特說：「當心懂得運用公式的那些人！」這些量化交易大師又被稱為寬客，與索羅斯這樣靠直覺買賣的傳...

最刺激的金融紀實報導！《華爾街日報》資深記者、《撼動華爾街的數學鬼才》、《暗池》作者精彩力作！一窺億萬交易員和高風險危機預測師如何靠極端事件，獲取巨額獲利如果你是《黑天鵝效應》的忠實讀者，這部精采絕倫的著作你絕不能錯過！納西姆．尼可拉斯．塔雷伯靠著《黑天鵝效應》聲名大噪，然而，他不僅是紙上談兵的學者，他還是優秀的交易員，把黑天鵝不可預知的特性，運用在投資上，為自己帶來豐碩的獲利。作者史考特‧派特森（Scott Patterson）以塔雷伯為主角，深入探究億萬交易員和高風險危機預測師的世界，揭露他們如何憑藉極端事件，賺進巨大的財富。我們的世界無疑變得更極端了，疫情、氣候變遷、大國對立、網路攻擊、政治激化——放眼望去，幾乎處處都有混亂迫近，脅迫著數以兆計的資產，但，市場哀鴻遍野之時，為何卻有一批人大賺其錢？是危機預測奏效，還是背後有什麼獨門的交易策略？作者獨家採訪寰...

機器人大舉進駐股市，造成哪些天翻地覆的轉變？了解現今股市樣貌與運作內情，不容錯過的翔實紀錄！「寫得遠比麥可・路易士更詳盡、更具說服力。」——《紐約時報》「監管機構和股市的所有投資人都應該閱讀。」——《金融時報》＊＊＊＊＊＊市場無預警崩跌、V轉，竟沒人知道原因？因為，全球股市如今已經成為一個大暗池！不僅可能短時間內劇烈波動，而且牽一髮而動全身……►人類主掌的股市，暗藏什麼難以察覺的弊端？►交易大廳與證券交易員如何被電腦掃入歷史？行內人士討價還價完成交易後，才把價格公開讓大眾知道。專業經紀人利用內線消息，搶在客戶委託單前交易。交易現場所有人手忙腳亂地抄寫數字，交易過後產生數量驚人的文件和垃圾。資料錯誤百出或過於老舊，有時甚至只是毫無用處的雜訊……程式設計天才約書亞・列文痛恨華爾街的積習——內線消息、特殊買賣、有關係就沒關係、落伍而欠缺效率。遵奉「資訊...

A news-breaking account of the global stock market's subterranean battles, Dark Pools portrays the rise of the "bots"--artificially intelligent systems that execute trades in milliseconds and use the cover of darkness to out-maneuver the humans who've created them.In the beginning was Josh Levine, an idealistic programming genius who dreamed of wresting control of the market from the big exchanges that, again and again, gave the giant institutions an advantage over...

With the immediacy of today’s NASDAQ close and the timeless power of a Greek tragedy, The Quants is at once a masterpiece of explanatory journalism, a gripping tale of ambition and hubris, and an ominous warning about Wall Street’s future.In March of 2006, four of the world’s richest men sipped champagne in an opulent New York hotel. They were preparing to compete in a poker tournament with million-dollar stakes, but those numbers meant nothing to them. Th...

Die Welt wird immer extremer: Pandemien, Klimawandel, politische Radikalisierung, religiöser Fundamentalismus – all diese Entwicklungen bedrohen Billionen an Vermögenswerten. Doch es gibt eine Gruppe von Investoren, die in dieser Umgebung erst richtig gedeiht: die Chaos Kings.Einer der berühmtesten Vertreter dieser Gruppe: Hedgefonds-Manager Mark Spitznagel und sein Universa-Fonds. Scott Patterson hatte exklusiven Zugang zu den Universa-Strategen und beschreibt, wie Spitznagel mithi...

From the actor who played Gilmore Girls’ beloved Luke Danes comes a love letter to American diner fare.For Scott Patterson, diners have always felt like home. Long before he played Luke Danes—the gruff but soft-hearted owner of Stars Hollows’ neighborhood diner on the cult-favorite television show Gilmore Girls—Scott grew up in Southern New Jersey, famously known as diner country, where no matter the time, day or night, a booth and a good meal were always ...

Build, deploy, test, and run cloud-native serverless applications using AWS Lambda and other popular AWS servicesKey FeaturesLearn how to write, run, and deploy serverless applications in Amazon Web ServicesMake the most of AWS Lambda functions to build scalable and cost-efficient systemsBuild and deploy serverless applications with Amazon API Gateway and AWS Lambda functionsBook DescriptionServerless computing is a way to ru...

Discover the story of Australia in the Great War through the eyes and stories of John Murray – a would-be journalist, aspiring artist and young soldier. John’s dairies capture the history, events and experiences of Australians, as each instalment builds to tell the story of Australia’s journey from peacetime through to the war’s end. Share a young Australian’s hopes his insights; and his pain, as war changes the fabric of his world and his family. The diaries have been compiled through met...

James Patterson’s BookShots. Short, fast-paced, high-impact entertainment.We know you did it – and you won't get away with it.Accused of murdering five small children, Thomas Scott is released on bail. He faces devastated parents plotting revenge and a fiery detective taking the law into his own hands. But did he do it? The truth will blow you away.

You're a genius. Nobody plays the financial markets better than you. What could possibly go wrong?Quants - quantitative analysts - were the maths masterminds let loose on Wall Street in the belief that their brilliant, impregnable computer programs would always beat the market. But as the catastrophic events of 2007 and 2008 showed, their seemingly failproof methods were little more than ticking timebombs.Inspired by the 'Godfather of Quants' - maths-profes...