The text provides the general pathologist, clinician and pulmonary pathologist with a framework on how to work up a case of either non neoplastic or neoplastic lung disease and provide clinically relevant information to all involved in patient care. The basic understanding of radiologic findings and what they mean or how they are related to clinical and pathologic findings is addressed in detail. The implications of descriptive and diagnostic terms as well as the criteria for diagnosis and...

This atlas is designed as an easy-to-use reference guide that identifies and illustrates the key patterns of diffuse lung diseases observed on high-resolution computed tomography (HRCT) and then documents in more detail the characteristics and appearances of the individual diseases, grouped on the basis of their prevalent pattern. A further feature of the book is its interdisciplinary nature: contributions from experts in various specialties are tightly interwoven throughout and many patho...

This book provides state of the art information on the pathogenesis, diagnosis, and treatment of a range of inflammatory, autoimmune, and idiopathic neuromuscular disorders. The opening section discusses the differential diagnosis of acquired myopathies based on clinical, electrophysiological, muscle biopsy, and serological criteria, with special focus on the role of electromyography and antibody testing. Each of the relevant clinical entities is then discussed in detail, the coverage incl...

This book comprehensively describes alkaptonuria and ochronosis. Beginning with the history, genetics, pathophysiology and diagnostics of the disease, the authors subsequently present a detailed characterization of its clinical manifestation in the spine, peripheral joints, eyes, ears, visceral organs and respiratory tract, its pathological anatomy and histology, as well as differential diagnosis. This is complemented by the latest data on therapy and experimental models of alkaptonuria, a...

Ever since its discovery in 1742 the carotid body has remained an organ of mystery. Originally described as a ganglion, it was subsequently regarded as a gland, chromaffin paraganglion and non-chromaffin paraganglion. In 1928 it was shown to be a chemoreceptor with close associations with the function of baroreception in the adjacent carotid sinus and perhaps within its own substance. These discoveries led physiologists to embark on a series of elegant experimental studies on a number of a...

Many books have been written about the pathology of the major organs of the body such as the lungs, heart, gastrointestinal tract etc. Included in these are descriptions - often with a minor emphasis - of pathological conditions which affect their serosal surfaces. In this book I have endeavoured to reverse the process and treat the mesothelium as an organ in its own right, rather than being the "no man's land" between various major structures. A number of pathological conditions are commo...

The processes of distention and recoil have an essential role in the functions of arteries and lungs. In both organ systems, these processes involve to a great extent the connective tissues, in particular the manner in which the extracellular materials are arranged to afford such movements. This book concerns the microenvironment of the connective tissues in the walls of arteries and the stroma of lungs. Proteoglycans, collagen, and elastic fibers and their interrelationships are discussed...

Chronic obstructive pulmonary disease (COPD) ranges amongst the commonest diseases in the world. The relentless progression of the disease causes a pressing need for a better understanding of and therapies for COPD. This volume provides state-of-the-art information on the pathophysiology of COPD including an outlook on new therapies. It is of interest to researchers and clinicians in academia as well as in the pharmaceutical industry.

Smoking and Lung Inflammation is the first book directly related to chronic lung inflammation of its kind in several respects. First, the it focuses on both basic and clinical research on COPD, and the inflammatory mechanisms that function in these diseases. Second, it is unique with respect to scope of the discussion of the unusual characteristics of the immune response which occurs in these patients. Third, it includes knowledge being gained from translational research conducted through ...

Diagnostic Atlas of Non-Neoplastic Lung Disease provides the practicing pathologist with the tools necessary to synthesize diagnoses in biopsy and surgical specimens of non-neoplastic lung disease. Classification of non-neoplastic lung disease has become increasingly complex, especially in diffuse lung diseases where terminology has been changing and clinical and radiologic input is advocated for diagnosis. As a result, general surgical pathologists may feel ill-equipped to interp...

Diagnosis of parasitic lung diseases is often difficult as their clinical manifestations can mimic common respiratory illnesses and routine tests can fail to detect the infections. Parasitic Diseases of the Lungs is designed as a practical guide for pathologists who encounter parasitic diseases of the lung in their daily routine. The book comprises eight chapters. After discussion of the handling of lung biopsies from patients with suspected parasitic disease, individual chapters ...