Natural Product Drug Discovery: Highly Anticipated Natural Molecules, a new volume in the Drug Discovery Opinion series, provides a comprehensive examination of the role of natural products in innovative drug development. The book addresses the significant challenges that highly active natural molecules face in the drug development process, including issues related to bioavailability and potency. Sections present analyses of various classes of natural products, including polysaccharides, v...

This book provides a multifaceted examination of solid waste management methods, the preparation, properties, and application of solid waste materials in the remediation of various environmental media, as well as the combination of solid waste materials and artificial intelligence.Based on the latest research results and cutting-edge technologies from around the world, the contributors combine the design principles of solid waste materials with application examples, including a com...

Privileged Scaffolds in Drug Discovery is the most complete and up-to-date work in the area. Covering a wide range of privileged structures, it is a perfect reference for scientists involved in targeted drug development. The editors recruited epserts from several prestigious Chinese institutions to cover the areas of antiviral drugs, chalcone, pyrimidine, (benz)imidazoles, natural product-derived privileged scaffolds, N-Sulfonyl carboxamides, kinase inhibitors, antitumor molecules, antineu...

A novel strain of influenza A (H1N1) virus emerged and an outbreak of influenza A (H1N1) occurred worldwide in 2009 and 2010, posing a severe threat to the health of human beings. The two Editors work together in Beijing You An Hospital, to combat this type of influenza. This book, Radiology of**Influenza A (H1N1), is intended to provide first-hand clinical data and its scientific analysis, thus supporting sound clinical practice for influenza A (H1N1) prevention and treatment as ...

Longitudinal studies often incur several problems that challenge standard statistical methods for data analysis. These problems include non-ignorable missing data in longitudinal measurements of one or more response variables, informative observation times of longitudinal data, and survival analysis with intermittently measured time-dependent covariates that are subject to measurement error and/or substantial biological variation. Joint modeling of longitudinal and time-to-event data has e...

This book constitutes the thoroughly refereed post-conference proceedings of the 12th International Conference on Mobile Computing, Applications, and Services, MobiCASE 2021, held in November 2021. Due to COVID-19 pandemic the conference was held virtually.The 9 full papers were carefully reviewed and selected from 21 submissions. The papers are organized in two topical tracks: mobile application and deep learning, and mobile application with data analysis.

Comprehensive, systematic review of advances in key CRISPR/Cas technologies, such as TALENS and zinc finger nucleases, double-strand break repair techniques, insertion-based genome edits, base editing, guide RNAs, gRNA/Cas9 constructs and CRISPR/Cas off targetingCovers both techniques and their practical application to particular cereal and other cropsDiscusses challenges in regulating this emerging technology

This book constitutes the refereed proceedings of the 11th International Symposium on Parallel Architectures, Algorithms and Programming, PAAP 2020, held in Shenzhen, China, in December 2020.The 37 revised full papers presented were carefully reviewed and selected from 75 submissions. The papers deal with research results and development activities in all aspects of parallel architectures, algorithms and programming techniques.

Over-pumping of aquifers is a worldwide problem, mainly caused by agricultural water use. Among its consequences are the falling dry of streams and wetlands, soil subsidence, die-off of phreatophytic vegetation, saline water intrusion, increased pumping cost and loss of storage needed for drought relief.Stopping or reversing the trend requires management interventions. The North China Plain serves as an example. A management system is set up for a typical county. It contains three ...

This book aims to examine innovation in the fields of computer engineering and networking. The book covers important emerging topics in computer engineering and networking, and it will help researchers and engineers improve their knowledge of state-of-art in related areas. The book presents papers from The Proceedings of the 2013 International Conference on Computer Engineering and Network (CENet2013) which was held on 20-21 July, in Shanghai, China.

This book constitutes seven refereed workshops and symposiums, SpaCCS Workshops 2020, which are held jointly with the 13th International Conference on Security, Privacy, and Anonymity in Computation, Communication, and Storage, SpaCCS 2020, in Nanjing, China, in December 2020.The 48 papers were carefully reviewed and selected from 131 submissions and cover a broad range of topics on security, privacy and anonymity in computation communication, and storage, including the 11th Interna...

This book highlights the latest research findings, innovative research results, methods and development techniques, from both theoretical and practical perspectives, in the emerging areas of information networking, data and Web technologies. It gathers papers originally presented at the 5th International Conference on Emerging Internetworking, Data & Web Technologies (EIDWT-2017) held 10–11 June 2017 in Wuhan, China. The conference is dedicated to the dissemination of original contribution...