A leading figure in immunology takes readers inside the remarkably powerful human immune system.Winner of the CHOICE Outstanding Academic Title of the Choice ACRLThe immune system has incredible power to protect us from the ravages of infection. Boosted by vaccines, it can protect us from diseases such as measles. However, the power of the immune system is a double-edged sword: an overactive immune system can wreak havoc, destroying normal tissue and causin...

This volume is divided into three sections. Section I deals with factors that regulate the development and maturation of T cells and B cells and lymphocyte traffic. The significance of C-kit, Bcl-6, IL-7, and Vav in the development of T and B lymphocytes is discussed. A role of lymphotoxins and VAP-I in trafficking of leucocytes is reviewed. Finally, the trafficking and homing characteristics of T cell and B cell subsets, and the regulation of these processes during the immune response, is...

Written by an immunologist, A History of Immunology traces the concept of immunity from ancient times up to the present day, examining how changing concepts and technologies have affected the course of the science. It shows how the personalities of scientists and even political and social factors influenced both theory and practice in the field. With fascinating stories of scientific disputes and shifting scientific trends, each chapter examines an important facet of this discipline that h...

**"A real jewel of science history...brims with suspense and now-forgotten catastrophe and intrigue...Wadman’s smooth prose calmly spins a surpassingly complicated story into a real tour de force."—The New York Times“Riveting . . . [The Vaccine Race] invites comparison with Rebecca Skloot's 2007 The Immortal Life of Henrietta Lacks.”—NatureThe epic and controversial story of a major breakthrough in cell biology that led to the conquest of...

"One of the world's foremost virus hunters" ( Financial Times), Stanford University biologist Nathan Wolfe reveals the origins of the world's most deadly diseases and how we can combat and stop contagions.A "mix of biology, history, medicine, and first-hand experience [that] is potent and irresistible,"* The Viral Storm: The Dawn of a New Pandemic Age shares information Wolfe uncovered on his groundbreaking and dangerous research missions in the ju...

This thoroughly updated second edition of Fast Facts: Rheumatoid Arthritis provides an easy-to-read overview of how the condition is thought to develop and how it is diagnosed, monitored and treated. Written by two leading UK and US rheumatologists, it covers the many recent developments in this field, including: - Recently published classification criteria - The emerging role of anti-CCP autoantibodies - The latest developments in ultrasound and MRI - The association between RA and cardiovas...

Human Parasitology emphasizes a medical perspective while incorporating functional morphology, physiology, biochemistry, and immunology to enhance appreciation of the diverse implications of parasitism. Bridging the gap between classical clinical parasitology texts and traditional encyclopedic treatises, Human Parasitology appeals to students interested in the medical aspects of parasitology and those who require a solid foundation in the biology of parasites. This fourth edition has been ...

This book highlights progress and trends in the rapidly evolving field of complement-related drug discovery and spotlights examples of clinical applications. As an integral part of innate immunity and critical mediator in homeostatic and inflammatory processes, the human complement system has been identified as contributor to a large number of disorders including ocular, cardiovascular, metabolic, autoimmune, and inflammatory diseases as well as in ischemia/reperfusion injury, cancer and s...

Medicine is not only a science; it is also an art. It does not consist of compounding pills and plasters; it deals with the very processes of life, which must be understood before they may be guided.' Paracelsus (1493-1541)For thousands of years, people have sought ways to overcome the diseases and disorders of the body, with methods ranging from incantations, talismans and herbal cures to antibodies, vaccines and organ transplants.The Story of Medicine charts our remarkabl...

Book covers course with topics in infectious diseases in children and is intended for Pediatric Infectious disease clinical researchers, trainees, trainers, and all those who manage the research of children with infections and the children themselves. The conference is being supported by several societies and is sponsored by several pharmaceutical companies, such as Aventis, Baxter, Chiron Vaccines, Wyeth, etc. ToC reflects the scientific program found here: http://www.oxfordiic.org/#cours...

In the early years of the twentieth century, an awareness was growing among European Australians of an unexpected threat, one that seemed the very embodiment of the dark, ominous power of the Australian bush. To the Indigenous people of the Guugu Yimithirr nation, it was nguman; to the whites it was the taipan, an eight foot, lightning fast venomous snake whose bite meant certain death.Venom is an examination of European settlers' troubled and often antagonistic relationsh...

Complement has long been regarded as a pivotal effector arm of the innate immune response, eliciting important immunoregulatory functions in the context of inflammation and also serving as a vital link between the innate and adaptive immune response. In the post-genomic era, our knowledge of the innate immune system is enriched by findings that point to novel functions that do not strictly correlate with immunological defense and surveillance, immune modulation or Inflammation. Several stu...