Few, if any, genes have had the same level of impact on the field of evolutionary-developmental biology (evo-devo) as the Hox genes. These genes are renowned for their roles in patterning the body plans and development of the animal kingdom. This is complemented by the distinctive organisation of these genes in the genome, with them frequently being found as clusters in which gene position is linked to when and where the individual genes are expressed, particularly during embryogenesis. Th...

The first edition of William A. Guy's Principles of Forensic Medicine was published at the start of Victoria's reign; the final edition, from which these selections derive, was published towards the end, just a few years after the Whitechapel horrors had pushed the emerging science to the forefront of the public's consciousness. With this guide in hand, a detective could tell whether the victim had suffocated, drowned, been shot, stabbed, or struck by lightning, s...

Illuminating the processes and patterns that link genotype to phenotype, epigenetics seeks to explain features, characters, and developmental mechanisms that can only be understood in terms of interactions that arise above the level of the gene. With chapters written by leading authorities, this volume offers a broad integrative survey of epigenetics. Approaching this complex subject from a variety of perspectives, it presents a broad, historically grounded view that demonstrates the utili...

This is the first and only book, so far, to deal with the causal basis of evolution from an epigenetic view. By revealing the epigenetic "user" of the "genetic toolkit", this book demonstrates the primacy of epigenetic mechanisms and epigenetic information in generating evolutionary novelties. The author convincingly supports his theory with a host of examples from the most varied fields of biology, by emphasizing changes in developmental pathways as the basic source of evolutionary change...

Most eyesight problems are, despite widespread beliefs otherwise, entirely functional disorders. People with clear vision do certain things that people with blurry vision don't, and people with blurry vision do certain things that those with clear vision don't. Learning to see the way that people with clear vision do is the basis for seeing clearly.For whatever reason, you have gotten stuck in an abnormal way of using your eyes, causing your visual system to go haywire. Further comp...

Genetics and Evolution of Infectious Diseases is at the crossroads between two major scientific fields of the 21st century: evolutionary biology and infectious diseases. The genomic revolution has upset modern biology and has revolutionized our approach to ancient disciplines such as evolutionary studies. In particular, this revolution is profoundly changing our view on genetically driven human phenotypic diversity, and this is especially true in disease genetic susceptibility. Infectious ...

A single species of fly, Drosophila melanogaster, has been the subject of scientific research for more than one hundred years. Why does this tiny insect merit such intense scrutiny?Drosophila’s importance as a research organism began with its short life cycle, ability to reproduce in large numbers, and easy-to-see mutant phenotypes. Over time, laboratory investigation revealed surprising similarities between flies and other animals at the level of genes, gene netw...

With the emergence of the new field of evolutionary developmental biology we are witnessing a renaissance of Darwin's insights 150 years after his On the Origin of Species. Thus far, the exciting findings from 'evo-devo' have only been trickling into college courses and into the domain of non-specialists. With its focus on the human organism, Quirks of Human Anatomy opens the floodgates by stating the arguments of evo-devo in plain English, and by offering a cornucopia of interesting case ...

Thousands of lives are lost annually from diseases which could have been prevented. Hundreds of thousands, because of some preventable ailment, which partially or totally incapacitates them, are today living only a small part of their lives. Millions of dollars yearly are squandered on medicines, doctors and undertakers—much of which might have been saved by a right knowledge of the laws of health and hygiene. Even among the comfortably situated, or even well-to-do, robust, vigorous health...

In this landmark work, the author team led by Dr. Sean Carroll presents the general principles of the genetic basis of morphological change through a synthesis of evolutionary biology with genetics and embryology. In this extensively revised second edition, the authors delve into the latest discoveries, incorporating new coverage of comparative genomics, molecular evolution of regulatory proteins and elements, and microevolution of animal development.An accessible text, focus...

A fascinating study of the actions and antidotes of snake poison, including many case studies. Written by late-19th century physician Dr A. Mueller, who was the first to introduce strychnine injections to treat snake bites.

This series of volumes represents a comprehensive and integrated treatment of reproduction in vertebrates from fishes of all sorts through mammals. It is designed to provide a readable, coordinated description of reproductive basics in each group of vertebrates as well as an introduction to the latest trends in reproductive research and our understanding of reproductive events. Whereas each chapter and each volume is intended to stand alone as a review of that topic or vertebrate group, re...