Most people are familiar with the concept of a negative shift in pH balance (also called the acid/alkaline balance), but most are unaware of its relationship to other health problems and diseases. Acidosis—a condition in which the body is excessively acidic—is often at the root of many common health complaints. Acidosis can affect every level of the human body, including mental outlook, metabolism, organs, tissues, cells, molecules, atoms, and chromosomes. All too often, acidosis-related h...

The purpose of this book, which is written mainly for pharmacothera pists, is to draw the physician's attentions, through specific examples, to iatrogenic (i.e., diagnostically or therapeutically induced) carcino genesis. The book is not intended, however, to arouse public concern. It has been known for some time that each therapeutic measure has a risk-benefit ratio, the estimation of which requires an understanding of carcinogenic side-effects. The number of iatrogenic tumors published s...

Help Your Child Overcome Sensory Overload, One Activity at a TimeChildren with sensory processing disorder (SPD) or sensory processing challenges associated with attention-deficit hyperactivity disorder (ADHD), autism, or other developmental conditions experience the world very differently than other kids. They may react strongly to sounds, textures, and stimulation, finding even seemingly minor sensations intolerable. Other children with SPD hardly notice sensory stimulation at al...

Science reveals the truth about how our food is making us mad and fat.Are you depressed or struggling to lose weight? You are not alone. 1 in 4 people are taking antidepressants and two thirds of us are obese or overweight. Something is clearly very wrong. Mad Diet lifts the lid on what is really going on with our food and provides an easy guide to restoring your mind and waistline.Mad Diet provides a fresh new approach to healthy eating,...

This Brief defines competitive intelligence (CI) as a tool for making investment decisions within the pharmaceutical industry. It provides an overview of processes that the regulatory affairs professional must take into account when evaluating data impacting product-based risk evaluations. These apply particularly to evaluations that focus on outputs such as regulatory approval, or the commercial impact of product labeling on the sales forecast over a limited timeframe. The Brief also prov...

This authoritative volume provides a holistic picture of antibody-drug conjugates (ADCs). Fourteen comprehensive chapters are divided into six sections including an introduction to ADCs, the ADC construct, development issues, landscape, IP and pharmacoeconomics, case studies, and the future of the field. The book examines everything from the selection of the antibody, the drug, and the linker to a discussion of developmental issues such as formulations, bio-analysis, pharmacokinetic-pharma...

Achieve Optimal Health with the Top 25 Immunity-Boosting FoodsBuild immunity that beats disease and slows down aging while increasing your energyWho doesn't want fewer colds, softer skin, or youthful vitality? Frances Sheridan Goulart, author of the ever-popular Super Healing Foods, now brings you a program for the 25 foods that strengthen the body's six immune centers and help heal and reverse the most common ailments.Focusing on the top 25...

The volume aim to be a comprehensive overview of the drug and biologic development process that is often called “the valley of death” (pre-IND through approval) where high costs of studies and high rates of product failure are part of the drug development landscape. Imaging tools can serve in this period by adding high value data, the images and the kinetic information they can provide, and cost-effective development alternative tools which potentially improve pivotal study designs. Imagin...

What are ADHD? What does it mean to have ADHD? How can kids diagnosed with ADHD help themselves succeed in school, get along better at home, and form healthy, enjoyable relationships with peers? In kid-friendly language and a format that welcomes reluctant and easily distracted readers, this book helps kids know they’re not alone and offers practical strategies for taking care of oneself, modifying behavior, enjoying school, having fun, and dealing with doctors, counselors, and medication....

Today, young cosmetics researchers who have completed their graduate studies and have entered a cosmetics company are put through several years of training before they become qualified to design cosmetics formulations themselves. They are trained so that they can design formulas not by a process of logic but by heart, like craftsmen, chefs, or carpenters. This kind of training seems a terrible waste of labor and time. To address this issue and allow young scientists to design novel cosmeti...

"Forget that I am deaf and blind and think of me as an ordinary woman," wrote Helen Keller--but she was anything but ordinary.When Helen was growing up, there were no facilities to help handicapped students. Still, she learned to speak, read, and write, attended Radcliffe College, wrote five books, and lectured all over the world. It wasn't enough to prove that she could do anything. Helen wanted other handicapped people to know that they could, too. And Helen achieved her...

This book highlights the challenges facing quality assurance/quality control (QA/QC) in today's biopharmaceutical environment and presents the strategic importance and value generated by QA/QC for their involvement in control of manufacturing. It will put into perspective the need for a graded approach to QA/QC from early clinical trials through market approval. Since the first edition published in 2004, there have been more than 50 new regulatory guidances released by the Food and Drug Ad...