Featuring more than 525 paintings in Robert C. Jackson's iconic style of realism with a slyly irreverent twist, this beautiful book thoughtfully covers his midcareer works. Many of his signature themes are recognizable but now treated more deeply, the compelling nature of his art is intensified, and larger canvases prevail.Known especially for his realistic still-life paintings featuring objects such as soda crates, balloon dogs, and foods, Jackson creates playful, exuberant art tha...

Advances in cancer genomics are transforming our understanding of cancer, and have profound implications for its prevention, diagnosis, and treatment. Evolutionary dynamics suggests that as few as two mutations can cause transformation of normal cells into cancer stem cells. A process of Darwinian selection, involving a further three or more mutations, taking place over a period of years, can then result in progression to a life-threatening tumour. In many cases the immune response can rec...

It is estimated that 80 to 90% of drugs under development never make it to the marketplace due to insufficient clinical activity, unacceptable toxicity, rapid appearance of drug resistance, or other factors that should be, at least partially, predictable from preclinical testing. This new text asks the question, "How can we use computational method

Kathleen Erickson, M.D. works part time in THE CLINIC caring for young women whose needs range from counseling, to birth control, and to therapeutic abortion. Kathleen, a 38 year old widow with two children, is a very active pro-choice obstetrician and gynecologist. As such she receives many threats to her life, including a gunshot wound in the middle of the night. She is sued for malpractice after performing a legal therapeutic abortion. A charge of manslaughter is added when the plaintif...

Structural Biology in Immunology, Structure/Function of Novel Molecules of Immunologic Importance delivers important information on the structure and functional relationships in novel molecules of immunologic interest. Due to an increasingly sophisticated understanding of the immune system, the approach to the treatment of many immune-mediated diseases, including multiple sclerosis, systemic lupus erythematosus, rheumatoid arthritis, and inflammatory bowel disease has been dramatically alt...

**Learn how to stay true to and focus on your own creative vision when the world seems out of control, as bestselling author Austin Kleon offers advice, stories, and anecdotes that teach you how to persist in doing work that helps make a world worth living in.Keep Working. Keep Playing. Keep Creating.**In his previous books Steal Like an Artist and Show Your Work!, both New York Times bestsellers, Austin Kleon gave readers the keys to unlock their...

Pharmacology meets the rapidly emerging needs of programs training pharmacologic scientists seeking careers in basic research and drug discovery rather than such applied fields as pharmacy and medicine. While the market is crowded with many clinical and therapeutic pharmacology textbooks, the field of pharmacology is booming with the prospects of discovering new drugs, and virtually no extant textbook meets this need at the student level. The market is so bereft of such approaches that man...

*NATIONAL BESTSELLER**A WGN Radio Best Book of 2024**A Good Housekeeping Reads pick*A hilarious and incisive exploration of the joys of reading from a "beloved and wonderful writer" (George Saunders), teacher, bibliophile, and Thurber Prize SemifinalistWe read to escape, to learn, to find love, to feel seen. We read to encounter new worlds, to discover new recipes, to find connection across difference, or simply to pa...

This concise overview of the fundamental concepts of cancer biology is ideal for those with little or no background in the field. A summary of global cancer patterns introduces students to the general principles of how cancers arise and the risk factors involved. By focusing on fundamental examples of the signalling pathways within cells, the functional effects of DNA damage are explained. Later chapters then build on this foundation to provide a comprehensive summary of the major signalli...

This revised second edition covers the pharmacologic principles underlying the individualization of patient therapy and contemporary drug development, focusing on the fundamentals that underlie the clinical use and contemporary development of pharmaceuticals. Authors drawn from academia, the pharmaceutical industry and government agencies cover the spectrum of material, including pharmacokinetic practice questions, covered by the basic science section of the certifying examination offered ...

LEE CHILD says she's "a genius."P.D. JAMES called her "the most remarkable" of today's suspense writers.STIEG LARSSON loved her work so much, he named her in his novels.And now SARA PARETSKY returns with the most extraordinary novel of her legendary career: FALLOUT.Before there was Lisbeth Salander, before there was Stephanie Plum, there was...

**The New York Times bestseller and one of Barack Obama's Favorite Books of 2024"The gift book of the year, a volume that should have broad appeal and deliver many hours of pleasure to the recipient. The Work of Art is a gorgeous book.” —John Warner*, The Chicago Tribune*From former editor of New York magazine Adam Moss, a collection of illuminating conversations examining the very personal, rigorous, complex, and elusive work of making art**...