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Cell Engineering eBook Serie

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  • Cell Line Development

    Bewerkt door Mohamed Al-Rubeai ...
    Serie Boek 6 - Cell Engineering
    Mammalian cell lines command an effective monopoly for the production of therapeutic proteins that require post-translational modifications. This unique advantage outweighs the costs associated with mammalian cell culture, which are far grater in terms of development time and manufacturing when compared to microbial culture. The development of cell lines has undergone several advances over the ... Meer lezen

    148,39 €

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  • DNA Repair of Cancer Stem Cells

    Bewerkt door Elain Hurt, Stephanie M Cabarcas, Lesley A Mathews ...
    Serie series Biomedical and Life Sciences (R0)
    The existence of ‘cancer stem cells’ (CSCs) has been a topic of heated debate for the last few years within the field of cancer biology. Their continuous characterization in a variety of solid tumors has lead to an abundance of evidence supporting their existence. CSCs are believed to be responsible for resistance against conventional treatment regimes of chemotherapy and radiation, ultimately, ... Meer lezen

    133,55 €

  • Trends in Stem Cell Proliferation and Cancer Research

    Bewerkt door Rodrigo R. Resende, Henning Ulrich ...
    Serie series Biomedical and Life Sciences (R0)
    The book will discuss the molecular mechanisms of cancer diseases, stem cell proliferation and transformation into cancer cells beyond the physiological processes that occur in normal stem cell biology. Some of the key oncogenic events in cancer and their signaling pathways that regulate cell division cycle progression will be described considering prospects for using such knowledge in advanced ... Meer lezen

    190,79 €

  • Regenerative Medicine - from Protocol to Patient

    4. Regenerative Therapies I

    Bewerkt door Gustav Steinhoff ...
    Serie series Biomedical and Life Sciences (R0)
    Regenerative medicine is the main field of groundbreaking medical development and therapy using knowledge from developmental and stem cell biology as well as advanced molecular and cellular techniques. This collection of volumes on Regenerative Medicine: From Protocol to Patient, aims to explain the scientific knowledge and emerging technology as well as the clinical application in different organ ... Meer lezen

    95,39 €

  • Mitochondrial DNA, Mitochondria, Disease and Stem Cells

    Bewerkt door Justin C. St. John ...
    Serie series Biomedical and Life Sciences (R0)
    This volume investigates how the mitochondrial genome is transmitted, segregated, and inherited. It starts by describing mtDNA mutations and deletions and how these impact on the offspring’s well-being. It progresses to discuss how mutations to the mtDNA-nuclear-encoded transcription, replication and translational factors lead to mtDNA-depletion syndromes and how these affect cellular function and ... Meer lezen

    105,99 €

  • Hypoxia and Cancer

    Biological Implications and Therapeutic Opportunities

    Bewerkt door Giovanni Melillo ...
    Serie series Biomedical and Life Sciences (R0)
    The imbalance between rapidly proliferating tumor cells and inadequate and inefficient tumor vasculature leads to a decrease in oxygen levels (hypoxia and/or anoxia) in tumor tissues. Intra-tumor hypoxia profoundly affects the biological behavior of cancer cells, which become resistant to conventional therapies and acquire a more invasive and metastatic phenotype. Hypoxia is a hallmark of the ... Meer lezen

    133,55 €

  • Perspectives of Stem Cells

    From tools for studying mechanisms of neuronal differentiation towards therapy

    Bewerkt door Henning Ulrich ...
    Serie series Biomedical and Life Sciences (R0)
    Stem cells are fascinating cell types. They can replicate themselves forever while retaining the potential to generate progeny with speci?c functions. Because of these special properties, stem cells have been subjects of intensive investigation, from understanding basic mechanisms underlying tissue generation, to modeling human diseases, to application for cell replacement therapy. Stem cells come ... Meer lezen

    133,55 €

  • Biochemical Basis and Therapeutic Implications of Angiogenesis

    Bewerkt door Jawahar L. Mehta, Pankaj Mathur, Naranjan S. Dhalla ...
    Serie series Biomedical and Life Sciences (R0)
    This book covers the latest developments in the therapeutic implications of angiogenesis, ranging from angiogenesis in the brain, angiogenesis in cancer, angiogenesis’ role in atherosclerosis and heart disease as well as metabolic disorders and peripheral vascular disease. The book is comprehensive in its coverage of angiogenesis in a diverse set of diseases and examines the role of cellular and ... Meer lezen

    211,99 €

  • Biochemical Basis and Therapeutic Implications of Angiogenesis

    Bewerkt door Naranjan S. Dhalla, Jawahar Mehta ...
    Serie series Biomedical and Life Sciences (R0)
    Angiogenesis is a highly complex phenomenon where new blood vessels are formed for the supply of oxygen and nutrients in different organs of the body. It plays a critical role in both physiological processes such as growth and development as well as pathological processes including cancer and different types of tumors. Angiogenesis is also essential for the regeneration and survival of cells in ... Meer lezen

    210,94 €

  • Coxiella burnetii: Recent Advances and New Perspectives in Research of the Q Fever Bacterium

    Bewerkt door Rudolf Toman, Jean-Louis Mege, Robert A. Heinzen, James E. Samuel ...
    Serie series Biomedical and Life Sciences (R0)
    Coxiella burnetii is the etiological agent of Q fever, a zoonotic disease found worldwide. The bacterium is a fascinating example of intracellular parasitism that has uniquely evolved to thrive in the most inhospitable of cellular compartments-the phagolysosome. Understanding how C. burnetii resists the degradative functions of this vacuole, and the host cell functions coopted for successful ... Meer lezen

    190,79 €

  • Modeling Fragile X Syndrome

    Bewerkt door Robert B. Denman ...
    Serie series Biomedical and Life Sciences (R0)
    Introduction.-Probing Astrocyte Function in Fragile X Syndrome.- Neural Stem Cells.- Fragile X Mental Retardation Protein (FMRP) and the Spinal Sensory System.– The Role of the Postsynaptic Density in the Pathology of the Fragile X Syndrome.- Behavior in a Drosophila model of Fragile X.- Molecular and Genetic Analysis of the Drosophila Model of Fragile X Syndrome.- Fragile X Mental Retardation ... Meer lezen

    190,79 €

  • Stem Cells and Cell Therapy

    Bewerkt door Mohamed Al-Rubeai, Mariam Naciri ...
    Serie series Biomedical and Life Sciences (R0)
    With the discovery of stem cells capable of multiplying indefinitely in culture and differentiating into many other cell types in appropriate conditions, new hopes were born in repair and replacement of damaged cells and tissues. The features of stem cells may provide treatment for some incurable diseases with some therapies are already in clinics, particularly those from adult stem cells. Some ... Meer lezen

    85,85 €