Radiation therapy has developed and advanced dramatically in the last few decades. However, very little has been published or done in the area of biologically optimized treatment planning. Development of Biologically Optimized Radiation Therapy aims to fill and close an important gap in the literature with a well-focused and in-depth content.The book covers the biological, physical and clinical background of advanced biologically based radiation therapy optimization with focus on modern ra...

The collection of chapters in this proceedings volume brings together research from academic and industry scientists and clinical development experts who are focused on contemporary and emerging aspects of improving treatments employing biosurfaces. Interactions between biomaterial implants, devices, cell therapies, and whole organ transplants frequently trigger activation of body defense systems and responses that negatively affect the clinical outcome. Optimal tissue integration and modu...

Final FRCR 2B Viva: A Survival Guide presents a series of cases similar to those used in the FRCR exams and representative of everyday radiological practice. This invaluable collection of high quality images is accompanied by clear and concise explanations, enabling trainees to prepare fully for their FRCR 2B viva presentation. Covering the full range of imaging modalities and organ systems, it provides clinically important vignettes which help the reader to impress examiners and colleague...

Never before in the history of medicine has mankind faced such hope and peril as those of us poised to embrace the radical medical technologies of today.Eve Herold's Beyond Human examines the medical technologies taking shape at the nexus of computing, microelectronics, engineering, nanotechnology, cellular and gene therapies, and robotics. These technologies will dramatically transform our lives and allow us to live for hundreds of years. Yet, with these blessings come com...

Spine Imaging, a title in the popular Case Review Series, helps you effectively prepare for certification, recertification, and practice in spine imaging with case studies that test your knowledge of all essential topics. This medical reference book will show you how to make confident, final diagnoses through accurate pattern recognition, clinical correlation, and...

This book offers comprehensive information on all aspects of ELISA, starting with the fundamentals of the immune system. It also reviews the history of analytical assays prior to the advent of ELISA (enzyme-linked immunosorbent assay) and addresses the materials of choice for the fabrication of the platforms, possible biomolecular interactions, different protocols, and evaluation parameters. The book guides readers through the respective steps of the analytical assay, while also familiariz...

This book examines non-invasive, electrical-based methods for disease diagnosis and assessment of heart function. In particular, a formalized signal model is proposed since this offers several advantages over methods that rely on measured data alone. By using a formalized representation, the parameters of the signal model can be easily manipulated and/or modified, thus providing mechanisms that allow researchers to reproduce and control such signals. In addition, having such a formalized s...

As the biomedical engineering field expands throughout the world, clinical engineers play an evermore-important role as translators between the medical, engineering, and business professions. They influence procedure and policy at research facilities, universities, as well as private and government agencies including the Food and Drug Administration and the World Health Organization. The profession of clinical engineering continues to seek its place amidst the myriad of professionals that ...

How often have you been confronted with an image on a thoracic CT exam where you knew it didn't look 'normal', but you weren't sure whether it was 'abnormal' either? And if it is abnormal, is there a specific diagnosis you should be able to make directly off the images? Pearls and Pitfalls in Thoracic Imaging is your one-stop resource to answer questions such as: Is this a normal variant or a disease-related abnormality? Are these findings specific for an uncommon disease and if so what is...

The generation of tridimensional tissues, assembled from scaffolding materials populated with biologically functional cells, is the great challenge and hope of tissue bioengineering and regenerative medicine. The generation of biomaterials capable of harnessing the immune system has been particularly successful. This book provides a comprehensive view of how immune cells can be manipulated to suppresses inflammation, deliver vaccines, fight cancer cells, promote tissue regeneration or inhi...

This book introduces readers to the basic concepts of Heart Rate Variability (HRV) and its most important analysis algorithms using a hands-on approach based on the open-source RHRV software. HRV refers to the variation over time of the intervals between consecutive heartbeats. Despite its apparent simplicity, HRV is one of the most important markers of the autonomic nervous system activity and it has been recognized as a useful predictor of several pathologies. The book discusses all the ...

Recent technological advances have enabled comprehensive determination of the molecular composition of living cells. The chemical interactions between many of these molecules are known, giving rise to genome-scale reconstructed biochemical reaction networks underlying cellular functions. Mathematical descriptions of the totality of these chemical interactions lead to genome-scale models that allow the computation of physiological functions. Reflecting these recent developments, this textbo...