The creativity of the human mind was brilliantly displayed during the Florentine Renaissance when artists, mathematicians, astronomers, apothecaries, architects, and others embraced the interconnectedness of their disciplines. Artists used mathematical perspective in painting and scientific techniques to create new materials; hospitals used art to invigorate the soul; apothecaries prepared and dispensed, often from the same plants, both medicinals for patients and pigments for painters; ut...

This book provides a framework for computational researchers studying the basics of cancer through comparative analyses of omic data. It discusses how key cancer pathways can be analyzed and discovered to derive new insights into the disease and identifies diagnostic and prognostic markers for cancer. Chapters explain the basic cancer biology and how cancer develops, including the many potential survival routes. The examination of gene-expression patterns uncovers commonalities across mult...

Advances in the field of glycoprotein hormones necessitated a second international symposium on this topic, held March 11 to 14, 1993, in Santa Barbara, California, and again sponsored by Serono Symposia, USA. The meeting was twofold in its concept: (1) the dissemination of the current research in the field and (2) honoring three scientists who have greatly contributed to this field, Drs. Harold Papkoff, Robert Ryan, and Darrell Ward, upon their retirements. We were honored to have Dr. Joh...

A master class from four renowned Harvard professors—an anthropologist, a physician, a theologian, and a historian—on discovering wisdom in challenging times.In moments of uncertainty, to whom do we turn for solace and insight? How can we endure and overcome our own suffering? Harvard University professors Davíd Carrasco, Arthur Kleinman, Stephanie Paulsell, and Michael Puett turn to great thinkers, artists, and religious traditions not for definitive answers, but for lessons we ca...

**Now a docuseries from Ken Burns on PBS!The #1 New York Times bestseller from Walter Isaacson brings Leonardo da Vinci to life in this exciting new biography that is “a study in creativity: how to define it, how to achieve it…Most important, it is a powerful story of an exhilarating mind and life” (The New Yorker).**Based on thousands of pages from Leonardo da Vinci’s astonishing notebooks and new discoveries about his life and work, Walter Isaacson “deft...

Even in an age of soaring skyscrapers and cavernous sports stadiums, the cathedral of Santa Maria del Fiore in Florence still retains a rare power to astonish. Yet the elegance of the building belies the tremendous labour, technical ingenuity and bitter personal strife involved in its creation. For over a century after work on the cathedral began in 1296, the proposed dome was regarded as all but impossible to build because of its enormous size. The greatest architectural puzzle of its age...

Leonardo da Vinci's scientific explorations were virtually unknown during his lifetime, despite their extraordinarily wide range. He studied the flight patterns of birds to create some of the first human flying machines; designed military weapons and defenses; studied optics, hydraulics, and the workings of the human circulatory system; and created designs for rebuilding Milan, employing principles still used by city planners today. Perhaps most importantly, Leonardo pioneered an empirical...

Early in 1495, Leonardo da Vinci began work in Milan on what would become one of history's most influential and beloved works of art--The Last Supper. After a dozen years at the court of Lodovico Sforza, the Duke of Milan, Leonardo was at a low point personally and professionally: at 43, in an era when he had almost reached the average life expectancy, he had failed, despite a number of prestigious commissions, to complete anything that truly fulfilled his astonishing promise. His latest f...

Leonardo da Vinci was an Italian Renaissance polymath: painter, sculptor, architect, musician, mathematician, military-engineer, inventor, anatomist, geologist, cartographer, botanist, and writer. His genius, perhaps more than that of any other figure, epitomized the Renaissance humanist ideal. Leonardo has often been described as the archetype of the Renaissance Man, a man of "unquenchable curiosity" and "feverishly inventive imagination". He is widely considered to be one of the greatest...

An epic cultural journey that reveals how Venetian ingenuity and inventions—from sunglasses and forks to bonds and currency—shaped modernity.How did a small, isolated city—with a population that never exceeded 100,000, even in its heyday—come to transform western civilization? Acclaimed anthropologist Meredith Small, the author of the groundbreaking Our Babies, Ourselves examines the the unique Venetian social structure that was key to their explosion of c...

"Walker here pairs off proto-architect Filippo Brunelleschi and doormaker Lorenzo Ghiberti in an often engaging version of Quattrocento Smackdown." — Library JournalJoining the bestsellers Longitude and Galileo's Daughter, this is a lively and intriguing tale of two artists whose competitive spirit brought to life one of the world's most magnificent structures and ignited the Renaissance.The dome of the Santa Maria del Fiore, the gr...

Leonardo da Vinci was one of history's true geniuses, equally brilliant as an artist, scientist, and mathematician. Readers of The Da Vinci Code were given a glimpse of the mysterious connections between math, science, and Leonardo's art. Math and the Mona Lisa picks up where The Da Vinci Code left off, illuminating Leonardo's life and work to uncover connections that, until now, have been known only to scholars.Bülent Atalay, a distinguished scientist an...