Targeted Therapy in Translational Cancer Research for the Translational Oncology series provides a comprehensive overview of recent developments in our understanding of tumor biology, elucidates the roles of targets and pathways involved in carcinogenesis, and describes current state-of-the-art anticancer therapy, as well as the most promising areas of translational research and targeted therapy.Introduces cutting-edge ‘bench to bedside and back’ breakthroug...

Do you manage patients with gastrointestinal cancer?Do you need a rapid reference handbook to guide you through your diagnosis and management options?If so, then Handbook of Gastrointestinal Cancer is the book for you, providing clear, practical guidance to the diagnosis and clinical management of all forms of GI cancer, in a highly accessible format. Perfect for GI/Oncology trainees and junior gastroenterologists/oncologists and designed for point-...

"The Dance Festivals of the Alaskan Eskimo" by Ernest William Hawkes is a captivating exploration of the rich cultural heritage of the Alaskan Eskimo communities. Through detailed observations and vivid descriptions, Hawkes delves into the significance of dance festivals, which serve as vital expressions of identity, tradition, and community bonding. The book highlights various dances, their meanings, and the role they play in the social fabric of Eskimo life, showcasing the intricate rela...

Autophagy in Health and Disease offers an overview of the latest research in autophagy with a translational emphasis. This publication takes scientific research in autophagy a step further and offers integrated content with advancements in autophagy from cell biology and biochemical research to clinical treatments. A necessary reference for the bookshelf of medical and scientific researchers and students, Autophagy in Health and Disease presents high quality, reputable information on autop...

This comprehensive book captures and compiles new and current information on hematologic malignancies. New knowledge of cellular disease processes, molecular pathology, and cytogenetic, epigenetic and genomic changes has influenced the current outlook toward haematological malignancies. This recent and ongoing expansion of knowledge on malignant hematology has not previously been utilized to its full capacity due to its diffuse distribution scattered over the internet and research publicat...

Vitamin D, a steroid hormone, has mainly been known for its effects on bone and osteoporosis. The current therapeutic practices expand into such markets as cancer research, pediatrics, nephrology, dermatology, immunology, and genetics. This 3e includes over 100 chapters covering everything from chemistry and metabolism to mechanisms of action, diagnosis and management, new analogs, and emerging therapies. This complete reference works is a must-have resource for anyone working in endocrino...

There has been major growth in understanding immune suppression mechanisms and its relationship to cancer progression and therapy. This book highlights emerging new principles of immune suppression that drive cancer, and it offers radically new ideas about how therapy can be improved by attacking these principles. Following work that firmly establishes immune escape as an essential trait of cancer, recent studies have now defined specific mechanisms of tumor immune suppression. It also dem...

A practice-oriented desktop reference for medical professionals, toxicologists and pharmaceutical researchers, this handbook providessystematic coverage of the metabolic pathways of all major classes of xenobiotics in the human body. The first part comprehensively reviewsthe main enzyme systems involved in biotransformation and how they are orchestrated in the body, while parts two to four cover the threemain classes of xenobiotics: drugs, natural products, environment...

METABOLIC SYNDROMEA comprehensive look at the fight against the metabolic syndrome epidemicIncreasing risk of cardiovascular disease and diabetes, the metabolic syndrome is a world health problem that demands attention from all levels of the health care industry. Metabolic Syndrome: Underlying Mechanisms and Drug therapies extensively covers the metabolic syndrome with an emphasis on drug discovery efforts, providing a context of m...

The International Textbook of Diabetes Mellitus has been a successful, well-respected medical textbook for almost 20 years, over 3 editions. Encyclopaedic and international in scope, the textbook covers all aspects of diabetes ensuring a truly multidisciplinary and global approach. Sections covered include epidemiology, diagnosis, pathogenesis, management and complications of diabetes and public health issues worldwide. It incorporates a vast amount of new data regarding the scien...

“Drs. Butterfield, Kaufman and Marincola on behalf of the SITC have created a comprehensive must-have resource covering the basic and translational science behind approved and investigational immune therapies, and disease-by-disease clinical application of the therapies, written by leaders in the field. The textbook will be highly valuable reading for those just entering the field and for experienced scientists and clinicians looking to expand their knowledge base.”—Mario ...