The clinical management of patients with diabetes is rapidly evolving. Evidence-based Management of Diabetes provides a succinct summary of a range of topics, including areas where there is already well developed evidence for a particular treatment, but also those areas where the evidence is perhaps doubtful or there is some associated controversy or ambiguity. Where possible throughout the book treatment recommendations are given based on the available evidence and practice guidelines. Th...

There's a running joke among radiologists: finding a tumor in a mammogram is akin to finding a snowball in a blizzard. A bit of medical gallows humor, this simile illustrates the difficulties of finding signals (the snowball) against a background of noise (the blizzard). Doctors are faced with similar difficulties every day when sifting through piles of data from blood tests to X-rays to endless lists of patient symptoms.Diagnoses are often just educated guesses, and prognoses less...

This concise, easy to read title is designed for clinical teachers looking to refine their approach to teaching professional attitudes and basic skills to medical students. Doctors differ in values, training and practice setting, and eventually they adopt diverse approaches to patient interviewing, data collection and problem-solving. As a result, medical students may encounter significant differences in the clinical methods of their tutors. For example, some doctors encourage patients’ na...

Nutritional Biochemistry takes a scientific approach to nutrition. It covers not just "whats"--nutritional requirements--but why they are required for human health, by describing their function at the cellular and molecular level. Each case study either leads to a subsequent discovery or enables an understanding of the physiological mechanisms of action of various nutrition-related processes. The text is "picture-oriented" and the commentary is directed towards explaining graphs, figures, ...

This timely volume provides an overview to the causes, effects on systems and clinical approaches of metabolic acidosis. Beginning with a basic understanding of the physiology, pathophysiology and development of this disease, subsequent chapters cover the characteristics and context of the processes that can cause it and a thorough presentation of management strategies. Recommended treatments include those carried out by the health care provider as well as the individual patient, such as d...

Nutrition and Metabolism: Underlying Mechanisms and Clinical Consequences brings together internationally recognized experts to comprehensively review our current understanding of how nutrition interacts with the genetic substrate as well as environmental-exogenous factors, including physical activity or the lack thereof, to result in insulin resistance and the metabolic syndrome.After presenting the scope of the problem, the first major part of the book is devoted to genetics and ...

F. Kruck It is a great pleasure for me to welcome you to the workshop on Natriuretic Hormone here in Bonn. For quite a long time we have been considering the possibility of assem bling scientists who are concerned with and interested in the problem of a possible humoral natriuretic activity. Work has been done on this topic in different parts of the world, partially with different methods and sometimes also with different and contlict ing results. And thus we thought it could be very benef...

The cytochemical bioassay system was described in a short abstract in 1971, and more fully, in the cytochemical bioassay of corticotrophin, in 1972. Since then, cytochemical bioassays have been described for several polypeptide hormones, and these assays are already widely used. It is expedient that the subject should be reviewed, as it is in this monograph, by one writer who has had the good fortune to have taken part in the growth of cytochemistry from its early origins to its present po...

Progress in Myeloma: Biology of Myeloma is a collection of research studies dealing with the clinical and experimental plasma cell tumors. This work is composed of 14 chapters that provide a particularly advantageous basis for defining in biochemical and genetic terms the nature of critical alterations in the neoplastic transformation of immunoglobulin producing cells. The introductory chapters survey the epidemiology of multiple myeloma and related plasma cell disorders, as well as the me...

The field of gender-specific medicine examines how normal human biology and physiology differ between men and women and how the diagnosis and treatment of disease differs as a function of gender. This revealing research covers various conditions that predominantly occur in men as well conditions that predominantly occur in women. Among the areas of greatest difference are cardiovascular disease, mood disorders, the immune system, lung cancer as a consequence of smoking, osteoporosis, diabe...

It is well-established, through extensive peer-reviewed published research, that physical activity and exercise training can impact the reproductive endocrine system of women. This ground-breaking, comprehensive title presents a range of unique insights into the opposite question: how the reproductive endocrine system of women affects their exercise ability. More precisely, the thematic question explored in this work is: if exercise affects reproductive hormones, conversely then could ...