The submersed cultivation of organisms in sterile containments or fermenters has become the standard manufacturing procedure, and will remain the gold standard for some time to come. This book thus addresses submersed cell culture and fermentation and its importance for the manufacturing industry. It goes beyond expression systems and integrally investigates all those factors relevant for manufacturing using suspension cultures. In so doing, the contributions cover all industrial cultivati...

The promise of a regenerative medicine -- the regrowth of lost limbs and organs, new hope for patients with Alzheimer's or multiple sclerosis, the "cellular fountain of youth" -- sounds like science fiction, but it's real and on the cutting edge of medicine. Veteran medical journalist Karen van Kamped looks at this new technology through the stories of the scientists who are creating it and the ethical and legal questions with which they must deal. Many companies and universities in Canada...

A Best Book of the YearSeed Magazine • Granta Magazine • The Plain-DealerIn this fascinating and utterly engaging book, Carl Zimmer traces E. coli's pivotal role in the history of biology, from the discovery of DNA to the latest advances in biotechnology. He reveals the many surprising and alarming parallels between E. coli's life and our own. And he describes how E. coli changes in real time, revealing billions of year...

An award-winning journalist investigates how scientists and citizens around the world are re-tooling our senses-and what their discoveries are teaching us about the nature and future of human perceptionHow do we know what's real? That's not a trick question: sensory science is increasingly finding that we don't perceive reality: we create it through perception. In We Have the Technology, science writer Kara Platoni guides us through the latest developments...

Computational biology drives discovery through its use of high-throughput informatics approaches. This book provides a road map of the current drug development process and how computational biology approaches play a critical role across the entire drug discovery pipeline. Through the use of previously unpublished, real-life case studies the impact of a range of computational approaches are discussed at various phases of the pipeline. Additionally, a focus section provides innovative visual...

This is the textbook and reference resource that instructors, students, and researchers in biomedical optics have been waiting for. Comprehensive and up to date, it covers a broad range of areas in biomedical optics, from light interactions at the single-photon and single-biomolecule levels, to the diffusion regime of light propagation in tissue. Subjects covered include spectroscopic techniques (fluorescence, Raman, infrared, near-infrared, and elastic scattering), imaging techniques (dif...

Developing directly from Fuller's recent book Humanity 2.0, this is the first book to seriously consider what a 'post-' or 'trans'-' human state of being might mean for who we think we are, how we live, what we believe and what we aim to be.

The most comprehensive and up-to-date optics resource availablePrepared under the auspices of the Optical Society of America, the five carefully architected and cross-referenced volumes of the Handbook of Optics, Third Edition, contain everything a student, scientist, or engineer requires to actively work in the field. From the design of complex optical systems to world-class research and development methods, this definitive publication provides unparalleled access to th...

This book is devoted to the engineering of protein-based nanostructures and nanomaterials. One key challenge in nanobiotechnology is to be able to exploit the natural repertoire of protein structures and functions to build materials with defined properties at the nanoscale using “bottom-up” strategies. This book addresses in an integrated manner all the critical aspects that need to be understood and considered to design the next generation of nano-bio assemblies. The book covers first the...

Skin Tissue Models provides a translational link for biomedical researchers on the interdisciplinary approaches to skin regeneration. As the skin is the largest organ in the body, engineered substitutes have critical medical application to patients with disease and injury – from burn wounds and surgical scars, to vitiligo, psoriasis and even plastic surgery. This volume offers readers preliminary description of the normal structure and function of mammalian skin, exposure to clinical probl...

Cheese is a significant part of European culture and its production, both industrial and artisanal, is a significant economic activity. Smear cheeses are one element of that diverse cultural and economic activity. And they are an ecological niche which illustrates the diversity of, especially, though not exclusively, actinomycetes. Mainstream ecology looks at the oceans, soil, rhizosphere, human microbiomes and plant, insect and marine animal symbionts which influence the climate, agricult...

The molecular age has brought about dramatic changes in medical microbiology, and great leaps in our understanding of the mechanisms of infectious disease. Molecular Medical Microbiology is the first book to synthesise the many new developments in both molecular and clinical research in a single comprehensive resource.This timely and authoritative three-volume work is an invaluable reference source of medical bacteriology. Comprising more than 100 chapters, organized into 17 major sections...