Surgical Treatment of Atrial Fibrillation: A Comprehensive Guide to Performing the Cox-Maze IV Procedure is the first all-inclusive description of this rapidly growing surgery, setting the standard in the field. The Cox-Maze IV procedure is a complex surgery, and its success depends critically on correct execution. With FDA approval, the first RF ablation device for treatment of the Cox-Maze IV procedure has become more important than ever to combine scientific information for the procedur...

Medical Ethics - General Practice: The Integrative Approach Series - ‘Ethics’ is a word derived from the Greek ethikos, which means ‘habit’ or ‘custom’. Put simply, in modern usage it is the study of how we ought to live or act in response to the situations confronting us in daily life. Medical ethics in particular is a branch of bioethics and is the study of how we ought to live or act as doctors. Ethics, being a branch of philosophy, relates to things such as ‘right’, ‘wrong’, ‘...

This pocket-sized manual serves as a concise and ideal reference work for therapeutic approaches using apheresis, Covering both basic theory and clinical details to facilitate improved treatment and patient outcomes, the text considers a variety of diseases, including myasthenia gravis, multiple sclerosis, Guillain-Barre syndrome, chronic inflammatory demyelinating polyneuropathy, nephrotic syndrome, TTP/TMA, dilated cardiomyopathy, and many other conditions. The books also reviews the gro...

Coronary Artery Disease: From Biology to Clinical Practice links the most important basic concepts of atherosclerosis pathophysiology to treatment management of coronary artery disease. Comprehensive coverage starts with the basic pathophysiologic mechanisms of the disease, including molecular and genetic mechanisms, cells interaction and inflammation. In addition, sections on novel anti-atherosclerotic therapies and a thorough understanding of the recent trends in clinical management roun...

Precision Medicine: Tools and Quantitative Approaches discusses precision and personalized medicine, two relevant topics that are revolutionizing diagnostics and treatment, while also providing a shift toward prevention. The book covers the most relevant features and explanations underlying developments in the field. A timely review on prerequisites, causes and consequences is given. Unique to this book is a combined view on technical and data analysis aspects that is mandatory for obtaini...

This complete, yet concise, guide introduces you to the rapidly developing field of high throughput screening of biomaterials: materiomics. Bringing together the key concepts and methodologies used to determine biomaterial properties, you will understand the adaptation and application of materomics in areas such as rapid prototyping, lithography and combinatorial chemistry. Each chapter is written by internationally renowned experts, and includes tutorial paragraphs on topics such as bioma...

This book describes the fundamental biology and mechanics of the vasculature and examines how this knowledge has underpinned the development of new clinical modalities, including endovascular treatment and vascularization of reconstructed tissue for regenerative medicine. Vascular engineering is a multidisciplinary field integrating vascular biology, hemodynamics, biomechanics, tissue engineering, and medicine. Each chapter offers insights into the dynamics of the circulatory system and ex...

xii a second edition might be in order, and readily agreed. Although the basic principles remain the same, discussions with analysts, laboratory supervisors, and managers indicated many areas where improve ments could be made. For example, new chapters have been added on sampling and quality assurance; laboratory facilities and quality assurance; and auditing for quality assurance. Very little of the first edition has been discarded, but many topics have been expanded considerably. The cha...

Designing Healthcare That Works: A Sociotechnical Approach takes up the pragmatic, messy problems of designing and implementing sociotechnical solutions which integrate organizational and technical systems for the benefit of human health. The book helps practitioners apply principles of sociotechnical design in healthcare and consider the adoption of new theories of change. As practitioners need new processes and tools to create a more systematic alignment between technical mechanisms and ...

Antibody-directed enzyme prodrug therapy (ADEPT) directly addresses the major problem in cancer chemotherapy-its lack of selectivity. Antibody delivery combined with the amplification provided by the enzymatic activation of prodrugs enables selection to be made between tumour and normal tissue. ADEPT offers a novel field of opportunities in the therapy of systemic cancer and may be a major advance for the treatment of solid tumours.This book is the first to describe ADEPT in detail....

This volume examines the advances of invasive monitoring by means of biosensors and microdialysis. Physical and physiological parameters are commonly monitored in clinical settings using invasive techniques due to their positive outcome in patients’ diagnosis and treatment. Biochemical parameters, however, still rely on off-line measurements and require large pieces of equipment. Biosensing and sampling devices present excellent capabilities for their use in continuous monitoring of patien...

This invaluable resource discusses clinical applications with effects and side-effects of applications of stem cells in liver, lung and heart regeneration. All chapters are contributed by pre-eminent scientists in the field and covers such topics as cell therapy in the treatment of cirrhosis and other liver, heart and lung diseases, characteristics of hepatic progenitor cells, future directions of the discussed therapies and much more.Liver, Lung and Heart Regeneration and...