A variety of new cancer therapy modalities are discussed and evaluated in this book. It aims to demonstrate that the combination of classical chemo- and radiotherapy with new approaches in the field of immunotherapy can result in an improved treatment modality. Immunotherapy in this context consists of therapy with monoclonal antibodies, hematopoietic growth factors and other lymphokines. Results of early clinical trials with IL-2, GM-CSF and monoclonal antibodies against gastrointestinal ...

Although pediatric surgery is a distinct and evolving specialty, it still remains an integral part of most general surgical and paediatric medical practice. Nevertheless, surgery in children does differ from adult practice in various fundamental ways, and there are key physiological and anatomical differences that constantly need underlining. Progress and improvement in outcome has also been rapid but it is sometimes difficult for practitioners to keep themselves up-to-date with the usual ...

The proposal for this book is to offer a systematic description of the most frequent complications occurring in the three parts of the digestive tract: HPB, Upper GI and colorectal tracts. Every complication, from esophageal to the rectum, is described systematically through two or three practical cases as has been treated by actual surgical practices of authors serving as surgeon practitioners. Description of the case, presentation of indication for surgery, type of primary surgical inter...

The authors aim to provide essential information on various clinical cases on urological cancers. The main messages are well referenced and the texts phrasing is written in a simple and user-friendly style. The book also contains summarizing tables and high quality original pictures. Several expert panels (American Urologists Association, European Association of Urologists, Association Française des Urologues, etc) are proposing guidelines aiming at providing detailed recommendations to th...

This comprehensive review of vascular disease in the vertebrobasilar circulation is based on Dr Louis R. Caplan's extensive experience and observation of patients from the New England Medical Center posterior circulation stroke registry. It benefits from an organized, uniform, and coherent analysis of all types of vascular disease involving the posterior circulation, presented by a single author who is one of the world's leading authorities on this topic. This new edition is fully updated ...

The first complete general study of acute necrotizing hemorrhagic pan creatitis was made in 1889 by Reginald Fitz. If we survey the therapeutic evolution of this severe illness, we may briefly summarize it into three pe riods: (a) resolutely surgical treatment, from approximately 1880 to 1938; (b) much more conservative treatment, from 1938 to 1963; and (c) a return to surgery, from 1963 onward. Hoffmann, in 1911, was probably the first to advocate the removal of the necrotic portion of th...

Introducing this monograph by expressing our heartfeIt thanks to all those who have contributed to its success may seem no more than a rhetorical exercise. However, at the same time we feel duty bound to add our sincere apologies, for we know that many of the dis tinguished authors of the various chapters have been hard put to find any relevant information in the existing literature. The plain fact is that very little has been said and written about pancreatic fistulas compared with other ...

Advances in Anesthesia 2012

Manual of Fast Track Recovery for Colorectal Surgery provides a broad overview on enhanced recovery, with expert opinions from leaders in the field regarding elements of enhanced recovery care that are generic and specific to colorectal surgery.This book covers the patient journey through such a programme, commencing with optimisation of the patient’s condition, patient education and conditioning of their expectations. Manual of Fast Track Recovery for Colorectal Surgery investigate...

Prostate cancer is the most common neoplasm in men and its management is very complex, in terms of both diagnosis and treatment. In recent years the value of multidisciplinary management within a prostate cancer unit has been increasingly recognized. Such a multidisciplinary approach within a specialized unit involves a variety of specialists, including urologists, oncologists, radiotherapists, radiologists and pathologists. This book describes in detail the advantages of multidisciplinary...

This text addresses all aspects of patient evaluation and care. This includes new findings in imaging that provide a better understanding of the extent of the lesion as well as its relationship with critical neuroanatomic function. The evolution of intraoperative imaging, functional brain mapping,and technology to identify tumor from brain is covered. This has significantly improved the ability of surgeons to more safely and aggressively remove tumors.More importantly, a better understandi...

This book presents a comprehensive survey in which internationally recognized experts discuss specific topics. Physiological and biophysical foundations of hemodynamics are reviewed and clinical tools to evaluate these newer parameters are described. Monitoring strategies integrating theoretical and practical aspects of hemodynamics in commonly encountered ICU conditions are presented. This Update represents the series' continuous effort to combine the most recent developments in ...