Once upon a time in a land not so far away lived a crazy rabbit hole. A gripping drama based on a true story and riddled with dark humor, from the insightful pen of K.L. Johns.In a small town where everyone knows your name but not all your secrets, Bailey faces the echoes of a turbulent past. Returning to her childhood home after twenty years she sifts through her childhood memories as humorous yet profound interactions with different characters shape her journey. Each encounter, l...

A gripping drama based on a true story and riddled with dark humor, from the insightful pen of K.L. Johns.Running from burnout, disillusionment, and a world that feels increasingly chaotic, Bailey's plan is simple. Go home. Regroup. Heal. Returning to her childhood island town after 20 years, her childhood home has other plans.She sifts through her memories as humorous yet profound interactions with different characters shape her journey, forcing her to confront the facade ...

A gripping drama based on a true story and riddled with dark humor, from the insightful pen of K.L. Johns.Running from burnout, disillusionment, and a world that feels increasingly chaotic, Bailey's plan is simple. Go home. Regroup. Heal. Returning to her childhood island town after 20 years, her childhood home has other plans.She sifts through her memories as humorous yet profound interactions with different characters shape her journey, forcing her to confront the facade ...

Clinically-focussed, with easily accessible tables and chapter summaries suitable for clinicians and researchers, this comprehensive book provides a systematic, critical evaluation of the current literature. An updated clinical decision-making algorithm specifically tailored to the antiretroviral drugs is also provided. The identified interactions are interpreted in the context of known mechanisms derived from clinical, preclinical, and in vitro data. The clinical relevance of the...

**"A real jewel of science history...brims with suspense and now-forgotten catastrophe and intrigue...Wadman’s smooth prose calmly spins a surpassingly complicated story into a real tour de force."—The New York Times“Riveting . . . [The Vaccine Race] invites comparison with Rebecca Skloot's 2007 The Immortal Life of Henrietta Lacks.”—NatureThe epic and controversial story of a major breakthrough in cell biology that led to the conquest of...

The leading clinical reference source on therapeutic antimicrobials, this latest edition contains up-to-date treatment guidelines and algorithms for most infections in an expanded, easy-to-read format. Composed by a team of expert contributing editors, this book is conveniently organized and tabbed for quick reference of drug toxicities, prophylaxis strategies, and dosage options. Now available with spiral binding, that allows the book to open flat for ease of use. Two compact, portable si...

Over the past decade, significant progress has been made in the theory and applications of pharmacodynamics of antimicrobial agents. On the basis of pharmacokinetic-pharmacodynamic modeling concepts it has become possible to describe and predict the time course of antimicrobial effects under normal and pathophysiological conditions. The study of pharmacokinetic-pharmacodynamic relationships can be of considerable value in understanding drug action, defining optimal dosing regimens, and in ...

This volume presents a collection of reviews derived from work presented at the Aegean Conference: “4th Crossroads between innate and adaptive immunity”. This meeting was the fourth in a series, and assembled a team of scientists working on mechanisms by which the innate immune system of the host senses pathogens, the cellular and signaling networks that orchestrate the innate response and antigen presentation and adaptive immunity. The importance of the crosstalk between innate immunity a...

Reports on the emergence and prevalence of resistant bacterial infections in hospitals and communities raise concerns that we may soon no longer be able to rely on antibiotics as a way to control infectious diseases. Effective medical care would require the constant introduction of novel antibiotics to keep up in the “arms race” with resistant pathogens.This book closely examines the latest developments in the field of antibacterial research and development. It starts with an overv...

Rare Diseases and Orphan Drugs shows that much of what we now know about common diseases has been achieved by studying rare diseases. It proposes that future advances in the prevention, diagnosis, and treatment of common diseases will come as a consequence of our accelerating progress in the field of rare diseases. Understanding the complex steps in the development of common diseases, such as cancer, cardiovascular disease, and metabolic diseases, has proven a difficult problem. Rare disea...

Chemokine Receptors and NeuroAIDS: Beyond the Co-receptor Function and Links to Other Neuropathologies focuses on unresolved or emerging issues concerning the role of chemokine receptors in neuronal injury and HIV neuropathology, including their ability to regulate fundamental neuronal and glial functions and their role in neurovirulence and neurotoxicity. Although the importance of these molecules in the CNS physiology and pathology is now apparent, these issues are still matter of debate...