This book discusses fabrication of functionalized gold nanoparticles (GNPs) and multifunctional nanocomposites, their optical properties, and applications in biological studies. This is the very first book of its kind to comprehensively discuss published data on in vitro and in vivo biodistribution, toxicity, and uptake of GNP by mammalian cells providing a systematization of data over the GNP types and parameters, their surface functionalization, animal and cell models. ...

Biotechnology is the major technology of the 21st century, yet few people realise how much it impacts on many aspects of human society. The defining aim of this new fifth edition is to re-establish the correct understanding of the term biotechnology. Using the straightforward style that made the previous editions of his textbook so popular, John Smith once again helps students with the deciphering and use of biological knowledge. He explains the historical developments in biotechnology and...

Antibiotics are truly miracle drugs. As a class, they are one of the only ones that actually cure disease as opposed to most drugs that only help relieve symptoms or control disease. Since bacteria that cause serious disease in humans are becoming more and more resistant to the antibiotics we have today, and because they will ultimately become resistant to any antibiotic that we use for treatment or for anything else, we need a steady supply of new antibiotics active against any resistant ...

This book is about “David & Goliath” R&D partnerships in pharmaceuticals—bilateral arrangements in which one partner is a smaller bioscience or academic organisation (David) and the other a large multinational corporation (Goliath). The past decade has seen a paradigm shift to a new distributed model of pharmaceutical R&D that seamlessly blends external partnerships with in-house efforts to generate innovative medicines and create new value. Smaller bioscience firms and academia have been ...

Bioreactors: Animal Cell Culture Control for Bioprocess Engineering presents the design, fabrication, and control of a new type of bioreactor meant especially for animal cell line culture. The new bioreactor, called the "see-saw bioreactor," is ideal for the growth of cells with a sensitive membrane. The see-saw bioreactor derives its name from its principle of operation in which liquid columns in either limb of the reactor alternately go up and down. The working volume of...

Patents protecting biotechnological invention are becoming ever more important. Because biotechnology has many differences with respect to other technologies, lessons learned in other fields of technology cannot simply be transferred to adopt a suitable strategy for dealing with biotechnology inventions.In this volume, general aspects of biopatent law will be discussed. This involves questions of patentability, including ethical issues and issues of technicality, as well as questio...

Evidence-Based Validation of Herbal Medicines brings together current thinking and practice in the areas of characterization and validation of natural products. This book reviews all aspects of evaluation and development of medicines from plant sources, including their cultivation, collection, phytochemical and phyto-pharmacological evaluation, and therapeutic potential. Emphasis is placed on describing the full range of evidence-based analytical and bio-analytical techniques used to chara...

Biotechnology is one of the major technologies of the twenty-first century. Its wide-ranging, multi-disciplinary activities include recombinant DNA techniques, cloning and the application of microbiology to the production of goods from bread to antibiotics. In this new edition of the textbook Basic Biotechnology, biology and bioprocessing topics are uniquely combined to provide a complete overview of biotechnology. The fundamental principles that underpin all biotechnology are explained an...

Biocompatibility of Dental Biomaterials details and examines the fundamentals of biocompatibililty, also including strategies to combat it. As biomaterials used in the mouth are subject to different problems than those associated with the general in vivo environment, this book examines these challenges, presenting the latest research and forward-thinking strategies. - Explores the fundamentals of dental biomaterials and their compatibility - Presents a thorough review of material specific ...

UHMWPE Biomaterials Handbook, Third Edition, describes the science, development, properties, and application of ultra-high molecular weight polyethylene (UHMWPE) used in artificial joints. UHMWPE is now the material of choice for joint replacements, and is increasingly being used in fibers for sutures. This book is a one-stop reference for information on this advanced material, covering both introductory topics and the most advanced developments. The third edition adds six new chapters on ...

The present book introduces an original (new) perspective on Cuba. This book revisits Cuba's choice, after the 1959 revolution, to develop an advanced healthcare and scientific system. It also introduces new aspects of the problem development/underdevelopment. From the start, every effort of the Cuban leadership and scientific community was driven by the primary purpose of meeting the country’s basic economic and social needs. Immediate key measures taken after the revolution included free...

This book deals with a subject of high interest and importance in all sectors, including biomedical, food, agriculture, energy, and environment. Biological systems are essential in nanotechnology, and many new applications are being developed by mimicking the natural systems. Approaching these topics from an engineering perspective, the book offers insight on the details of nanoscale fabrication processes as well as cell biology. The basics of biology and chemistry, with a focus on how to ...