Endocrine glands may be involved in patients with thalassemia major. In the last 20 years, new therapies have significantly improved life expectancy, while several endocrine abnormalities have been described in children, adolescents, and young adults suffering from thalassemia major.The practical objective of this book is to establish guidelines for the management of endocrine disorders underlying the various phases of thalassemic life. Internationally acknowledged experts give a st...

The Guest Editors have compiled a comprehensive issue that includes both disorders of endocrinology as well as diabetes. Authors have addressed the following clinical topics: disorders of menstruation, thyroid function; gender dysphoria; hypoglycemia in the nondiabetic child; preventing DKA; short- and long-term outcomes in diabetes, and whole genome sequencing in endocrinology. These topics represent the current knowedge in the field, and pediatricians will have the most updated clinical ...

New insights into the molecular biology of childhood leukemias have stimulated numerous advances in diagnostic methods, strategies for risk assessment and the development of novel therapy for genetic subtypes of the diseases. Fully revised and updated, this new edition of Childhood Leukemias provides the most comprehensive, clinically-oriented and authoritative reference dedicated to these diseases. Beginning with an overview of history, cell biology, and pathology, subsequent chapters rev...

The twin epidemics of obesity and type 2 diabetes mellitus (T2DM) continue to affect an ever increasing number of children, adolescents, and young adults. Management of Pediatric Obesity and Diabetes provides healthcare trainees and professionals with practical, comprehensive, and contemporary approaches to the pediatric patient at risk for obesity, T2DM, and related conditions. A unique guide on the subject, this volume provides clinical paradigms for diagnosis and management of pediatric...

A state-of-the-art and concise guide to the clinical management of pediatric endocrine disorders, the second edition of the highly regarded Pediatric Endocrinology: A Practical Clinical Guide covers the most common and challenging conditions seen by practicing endocrinologists and primary care physicians, including growth, hypothalamic, pituitary, adrenal, thyroid, calcium and bone, and reproductive disorders, as well as metabolic syndromes. This expanded second edition includes n...

This book provides a thorough and up-to-date discussion of key issues in the supportive care of children with cancer. A variety of frequently encountered situations is covered, including infections, metabolic, cardiopulmonary and neurologic emergencies, tumor lysis syndrome, pain, emesis, mucositis, thrombotic disorders, nutritional problems, hyperleukocytosis and acute abdomen. Throughout the emphasis is firmly on evidenced-based guidance developed from the relevant literature. Informatio...

JIMD Reports publishes case and short research reports in the area of inherited metabolic disorders. Case reports highlight some unusual or previously unrecorded feature relevant to the disorder, or serve as an important reminder of clinical or biochemical features of a Mendelian disorder.

This issue of Primary Care: Clinics in Office Practice, edited by Dr. Elizabeth K. McClain, is devoted to Primary Care for School-Aged Children. Articles in this issue include: Concussion and Trauma in Young Athletes; Addressing Obesity with Pediatric Patients and their Families in a Primary Care Office; HPV Vaccine Update; Parental Health Literacy and its Impact on Patient Care; Autism/ Pervasive Developmental Disorder; Challenges in Treating ADHD in Adolescents; Pediatric Oncology; Sudde...

A practical, clinically-oriented handbook of iron overload disorders giving a compact guide to normal iron metabolism, iron-related pathobiology, and the diagnosis and management of heritable and acquired iron overload disorders. Many of these disorders were discovered and characterized only in the last decade, and are unmentioned or inadequately described in most texts. Written by clinicians for clinicians, this handbook summarizes information on diverse iron overload conditions, includin...

Now in its third edition, this handbook describes the fundamentals of blood lipid metabolism and the connection between high cholesterol levels, atherosclerosis, and heart disease. The author of this handbook is an internationally known expert on lipid disorders who will discuss risk assessment, drug and dietary therapies, and special considerations in children, the elderly, and diabetic patients.

In developed countries the incidence of gestational diabetes lies between 1 and 8%. With the general decrease of perinatal mortality and morbidity, the complications arising from gestational diabetes have become more striking and significant. Moreover, impaired maternal carbohydrate metabolism may lead to non genetic fuel mediated disposition to diabetes in the offspring. The renewed topicality has greatly stimulated research in this field. This book provides both a general survey and the ...