Disturbances of iron metabolism, particularly iron deficiency, are among the most commonly overlooked or misinterpreted diseases. This is due to the fact that the determination of transport iron in serum or plasma, which used to be the test in conventional diagnosis, does not allow a representative estimate of the body’s total iron reserves. A proper estimate was formerly possible only by the costly and invasive determination of storage iron in the bone marrow, however, sensitive, well-sta...

Disturbances of iron metabolism, particularly iron deficiency, are among the most commonly overlooked or misinterpreted diseases. This is due to the fact that the determination of transport iron in serum or plasma, which used to be the test in conventional diagnosis, does not allow a representative estimate of the body’s total iron reserves. A proper estimate was formerly possible only by the costly and invasive determination of storage iron in the bone marrow, however, sensitive, well-sta...

Bone densitometry (BD) is an extraordinary clinical tool. It provides a safe, non-invasive window to the skeleton. Through that window, a physician can obtain vital clinical information that enhances diagnosis and improves patient management. Further, much has changed in the last decade to make bone densitometry the especially fascinating field of medicine it is today, incorporating imaging, physics, quantitative analysis, statistics, and computer technology -- all applied in the diagnosis...

Is the nephrology community facilitating excess cardiovascular deaths in patients with kidney failure and anemia by treating to a subnormal hematocrit? Why have clinicians and nephrologists permitted health insurance companies and the government to decide when anemia therapy should begin in persons with progressive kidney failure? Is iron the only variable that can be manipulated to maximize response to recombinant erythropoietin? Are we using too much intravenous iron in kidney failure pa...

This timely volume provides an overview to the causes, effects on systems and clinical approaches of metabolic acidosis. Beginning with a basic understanding of the physiology, pathophysiology and development of this disease, subsequent chapters cover the characteristics and context of the processes that can cause it and a thorough presentation of management strategies. Recommended treatments include those carried out by the health care provider as well as the individual patient, such as d...

Despite public perception, osteoporosis remains a widespread, devastating disease, and a very serious and costly public health threat. Early detection and treatment must be a priority for primary health care providers. Dual-energy X-ray absorptiometry (DXA) is the principal x-ray technology used to diagnose osteoporosis in its early, asymptomatic stages, to assess treatment efficacy, and to guide treatment decisions. It remains the gold standard today*.* A DXA Primer for the Practicing...

- Brings together up-to-date bone and mineral metabolism methods in one easily, accessible volume - Provides a quick reference for bone and mineral disorders - Addresses problems likely to be seen at all ages, from the pre-term infant to the centenarian - Ideal for practicing physicians, residents, medical students, and researchers

The ciliopathies are a group of rare diseases that often affect multiple systems within the body, and are caused by defects in the function or structure of cilia. When cilia go wrong, there are profound consequences; these are discussed in detail for the first time in Ciliopathies: a reference for clinicians. The book provides a clinical overview and reference to this newly emergent group of disorders ranging from Alström syndrome to putative ciliopathic disorders. Each chapter pr...

This book gives a complete description of online hemodiafiltration, in five sections. It is unique in the systematic and complete way in which hemodiafiltration is described. Each chapter is completed by a point-to-point summary of essential information, in a separate text box. Part of the book is dedicated to the theoretical background of convective clearance. In this part, safety issues and quality control is reviewed (especially on the quality of water for dialysis and substitution flui...

Now in its third edition, this handbook describes the fundamentals of blood lipid metabolism and the connection between high cholesterol levels, atherosclerosis, and heart disease. The author of this handbook is an internationally known expert on lipid disorders who will discuss risk assessment, drug and dietary therapies, and special considerations in children, the elderly, and diabetic patients.