For decades, the United States has led the effort to stem the spread of nuclear weapons, both among potential adversaries and among its allies and partners. The current state of deterrence and of the nonproliferation regime, however, is open to many doubts. What happens if the nonproliferation regime should break down altogether? What happens if extended deterrence should fail, and allies no longer believe in the credibility of the U.S. nuclear umbrella? What happens when the world has not...

In recent years, a number of molecular pathways and cellular processes that are essential for normal vertebrate development have been implicated in cancer initiation and progression. In this volume, leaders in the field of cancer genetics and developmental biology share recent insights into the importance of developmental pathways for tumorigenesis. These discoveries provide important avenues for innovative new approaches to treating some of the most challenging developmental tumors. - Pro...