In this issue of Hematology/Oncology Clinics, guest editors Drs. Nancy Berliner and Barbara A. Degar bring their considerable expertise to the topic of Hemophagocytic Syndromes. Top experts provide in-depth perspectives on these uncommon but potentially life-threatening disorders, including pathology of histiocytic disorders, genomic alterations in LCH, immunopathology of HLH, clinical characteristics and treatment of familial HLH, and much more. - Contains 11 relevant, practice-oriented t...

With hundreds of photographs and a wealth of information Yin Yu Tang tells the history of a traditional Chinese house and the fascinating stories of its occupants.In the late Qing dynasty, around the year 1800, a prosperous Chinese merchant named Huang built a house for his family in a remote village southwest of Shanghai. He named the house Yin Yu Tang which means Hall of Abundant Shelter—implying his desire for the building to shelter many of hi...

This issue of Hematology/Oncology Clinics of North America is devoted to Congenital and Acquired Disorders of Macrophages and Histiocytes. Guest Editors Nancy Berliner, MD and Barrett Rollins, MD have assembled a group of expert authors to review the following topics: Nosology of Langerhans Cell Histiocytosis (LCH); Cell of Origin of LCH; Genomic Changes in LCH; Clinical Treatment of LCH; Neurodegeneration in LCH; Pathogenesis of Hemophagocytic Lymphohistiocytosis (HLH); Familial HLH; HLH ...

This thoroughly updated second edition of Fast Facts: Rheumatoid Arthritis provides an easy-to-read overview of how the condition is thought to develop and how it is diagnosed, monitored and treated. Written by two leading UK and US rheumatologists, it covers the many recent developments in this field, including: - Recently published classification criteria - The emerging role of anti-CCP autoantibodies - The latest developments in ultrasound and MRI - The association between RA and cardiovas...

Pain Assessment and Pharmacologic Management, by highly renowned authors Chris Pasero and Margo McCaffery, is destined to become the definitive resource in pain management in adults. It provides numerous reproducible tables, boxes, and figures that can be used in clinical practice, and emphasizes the benefits of a multimodal analgesic approach throughout. In addition, Patient Medication Information forms for the most commonly used medications in each analgesic group can be copied and given...

Fully revised for the fifth edition, this outstanding reference on bone marrow transplantation is an essential, field-leading resource.Extensive coverage of the field, from the scientific basis for stem-cell transplantation to the future direction of researchCombines the knowledge and expertise of over 170 international specialists across 106 chaptersIncludes new chapters addressing basic science experiments in stem-cell biology, immunolog...

Expert, hands-on guidance for the practicing oncologist—from the leader in the field of cancer management—completely updated to reflect the latest advancesA Doody's Core Title for 2023, 2024 & 2026!Comprehensive and authoritative, The MD Anderson Manual of Medical Oncology delivers everything you need to accurately diagnose and effectively treat a wide range of cancers—including leukemia, lymphoma, myeloma, lung and breast...

The need for safe and effective use of medicines in children and WHO's initiative "Make Medicines Child Size" have boosted research and educational activities in the area of pediatric clinical drug research. This issue focuses on both general and specific aspects of neonatal and pediatric clinical pharmacology including ethics, pharmacogenomics, metabolomics, adverse drug reactions, pain medication, pulmonary hypertension and several other hot topics. The editors have been able to find out...

Ankylosing spondylitis (AS) and related forms of spondyloarthritis (SpA) are, as a group, as common as rheumatoid arthritis (RA). Their presenting clinical manifestations are wide-ranging and heterogeneous, and the patients end up seeing a variety of medical and surgical health care professionals before they get diagnosed. Early diagnosis and effective management can mitigate the severity of the disease, and make a meaningful difference in the lives of these patients.

Hepatologists, both researchers and front-line clinicians, now have a comprehensive guide to the treatment of patients with the HCV virus. This book focuses mainly on the efficacy and clinical use of antiviral therapies, including the use of antivirals post liver transplantation and in the presence of the HIV virus. It also explores the foundations for understanding antiviral therapies in HCV, such as the complex pharmacology and mechanisms of antiviral drugs. A 'late-breaking information'...

This book comprehensively reviews the current state of clinical trial methods in multiple sclerosis treatment, providing investigators, sponsors and specialists with current knowledge of outcome measures and study designs for disease and symptom management. The status of the rapidly evolving field of disease-modifying drugs is presented, with emphasis on the most promising therapies currently being tested. Experts discuss disease and symptom management for MS subtypes, including neuromyeli...

Edited by Drs. Jack Cush and Kathryn Dao, this issue of Rheumatic Disease Clinics of North America addresses one of the most significant issues facing the rheumatologist today––drug safety in a changing world where rheumatoid arthritis (RA) severity is less, patients are being identified and treated at a very early stage, and prevention is on the horizon. Topics covered include: communicating the risk of side effects, urate-lowering therapies, biphosphonates, biologics, malignancy risks, a...