Provides a highly visual, readily accessible introduction to the main events that occur during neural development and their mechanismsBuilding Brains: An Introduction to Neural Development, 2nd Edition describes how brains construct themselves, from simple beginnings in the early embryo to become the most complex living structures on the planet. It explains how cells first become neural, how their proliferation is controlled, what regulates the types of ne...

The dramatic story of one man’s recovery offers new hope to those suffering from concussions and other brain traumasIn 1999, Clark Elliott suffered a concussion when his car was rear-ended. Overnight his life changed from that of a rising professor with a research career in artificial intelligence to a humbled man struggling to get through a single day. At times he couldn’t walk across a room, or even name his five children. Doctors told him he would never fully re...

A “clear, witty, and engaging” (The Boston Globe) journey through the brain that connects neuroscience, biology, and culture. An “intellectual landmark” (Edward Shorter, Literary Review of Canada).The current view of delusions—the strange beliefs held by people with schizophrenia and other psychiatric illnesses—is that they are the result of biology gone awry, of neurons in the brain misfiring. In Suspicious Minds, Dr. Joel Gold and his b...

In 1997, Vagus Nerve Stimulation (VNS) therapy (Cyberonics, Houston, Texas) was approved by the United States Food and Drug Administration for the treatment of epilepsy refractory to antiepileptic medications. In 2005, VNS received FDA approval for treatment-resistant depression refractory to antidepressants, and Cyberonics recently received FDA approval for the clinical study of VNS for rapid cycling bipolar depression. Many researchers continue to investigate the anxiolytic effects of VN...

I remember several times when coming home tired after being on call , but I was always wanting to write something. Sometimes I had had an unusual scene, listened an interesting phrase or experienced a sad case. We are not able to express ourselves in a hospital, even when seriously ill, we dont have time. But that's how the book Thoughts from the hospital emerged. My book contains texts that I wrote during college, medical school and during my residency of neurosurgery. I could set the...

Neurosciences – a comprehensive approachThis textbook covers neuroscience from cellular and molecular mechanisms to behavior and cognitive processing. We also address evolution of the nervous system, computational neuroscience, the history of neuroscience as a discipline and neurophilosophy – to name but a few. The book provides the newest state-of-the-art knowledge about neuroscience from across the animal kingdom, with particular emphasis on model specie...

Glioblastoma is the most malignant brain tumor that still remains incurable. It is such a deadly disease that patients do not survive more than a few months after diagnosis. Our understanding of the histopathology and molecular mechanisms of formation of glioblastoma is rapidly advancing so as to provide us clues for devising rational therapeutic strategies for treatment of this malignancy. It is important that we continue to improve our knowledge about the pathogenesis of this devastating...

Glial Physiology and Pathophysiology provides a comprehensive, advanced text on the biology and pathology of glial cells.Coverae includes:the morphology and interrelationships between glial cells and neurones in different parts of the nervous systemsthe cellular physiology of the different kinds of glial cellsthe mechanisms of intra- and inter-cellular signalling in glial networksthe mechanisms of glial-neuronal communica...

Since the beginning of recorded history, law and religion have provided "rules" that define good behavior. When we obey such rules, we assign to some external authority the capacity to determine how we should act. Even anarchists recognize the existence of a choice as to whether or not to obey, since no one has seriously doubted that the source of social order resides in our vast ethical systems. Debate has focused only on whose system is best, never for an instant imagining that law, reli...

This book is designed to introduce the reader to the field of NMR/MRI at very low magnetic fields, from milli-Tesla to micro-Tesla, the ultra-low field (ULF) regime. The book is focused on applications to imaging the human brain, and hardware methods primarily based upon pre-polarization methods and SQUID-based detection. The goal of the text is to provide insight and tools for the reader to better understand what applications are best served by ULF NMR/MRI approaches. A discussion of the ...

This volume contains the Proceedings of the invited lectures of the Second International Sym posium on SEROTONIN from Cell Biology to Pharmacology and Therapeutics held in Houston, Texas September 15-18, 1992. The meeting was held under the co-sponsorship of the Serotonin Club, the Giovanni Lorenzini Medical Foundation, and the Fondazione Giovanni Lorenzini. This volume discusses the major exploration in knowledge that has occurred recently of the complex role that 5- hydroxytryptamine (se...

Till recently, mutations in genes were described in textbooks as deletions or point mutations. These mutations can be inherited from a parent or they are de novo alterations. The discovery in 1991 that human disease can be caused by large-scale ex pansion of highly unstable trinucleotide repeats has elucidated a new mutation mechanism, heritable unstable DNA. In the subsequent years more then 10 such disease genes have been identified. All dynamic mutations have been iden tified in neurolo...