Through the shadowy persona of “Deep Throat,” FBI official Mark Felt became as famous as the Watergate scandal his “leaks” helped uncover. Best known through Hal Holbrook’s portrayal in the film version of Bob Woodward and Carl Bernstein’s All the President’s Men, Felt was regarded for decades as a conscientious but highly secretive whistleblower who shunned the limelight. Yet even after he finally revealed his identity in 2005, questions about his true motivations persisted....

A BBC Radio 3 dramatisation of Vikram Seth's verse novel about the lives and loves of a group of twentysomethings in 1980s San FranciscoAward-winning novelist Vikram Seth is renowned worldwide for his magnum opus A Suitable Boy. But his dazzling debut, though less well-known, is equally innovative, masterly and ambitious. First published in 1986. and inspired by Pushkin's Eugene Onegin, it is written entirely in verse, comprising almost 600 stanza...

Recent advances in single molecule science have presented a new branch of science: single molecule cellular biophysics, combining classical cell biology with cutting-edge single molecule biophysics. This textbook explains the essential elements of this new discipline, from the state-of-the-art single molecule techniques to real-world applications in unravelling the inner workings of the cell. Every effort has been made to ensure the text can be easily understood by students from both the p...

Biophysics: Tools and Techniques for the Physics of Life covers the experimental, theoretical, and computational tools and techniques of biophysics. It addresses the purpose, science, and application of all physical science instrumentation, theoretical analysis, and biophysical computational methods used in current research labs.The book first presents the historical background, concepts, and motivation for using a physical science toolbox to understand biology. It...

Is the government too secret or not secret enough? Why is there simultaneously too much government secrecy and a seemingly endless procession of government leaks? The Transparency Fix asserts that we incorrectly assume that government information can be controlled. The same impulse that drives transparency movements also drives secrecy advocates. They all hold the mistaken belief that government information can either be released or kept secure on command.The Transpare...

This detailed new edition collects cutting-edge laboratory protocols, techniques, and applications in use by some of the leading international experts in the broad field of chromosome architecture. The book emphasizes the increasing physiological relevance of chromosome architecture investigation, manifest both through application of more complex bottom-up assays in vitro as well as through maintaining the native physiological context through the investigation of living, functiona...

Dass es in der Welt des Fußballs immer weniger um den Sport und immer mehr um schmutzige Geschäfte geht, ahnen die Fans nicht erst seit den Skandalen um die Fifa und die vermeintlich gekaufte WM 2006 in Deutschland., , Die Football Leaks bieten nun erstmals Einblicke in die Schattenwelt der Branche, offenkundig wird die grenzenlose Gier, die hinter den Kulissen des Weltfußballs herrscht. Der Whistleblower John hat dem SPIEGEL 1,9 Terabyte geheimer Daten übergeben: Rund 18,6 Millionen Dokum...

This book describes modern biophysical techniques that enable us to understand and examine dynamic processes of infection at the molecular level. Cutting-edge research articles, laboratory protocols, case studies and up-to-date reviews cover topics such as single-molecule observation of DNA replication repair pathways in E. coli; evolution of drug resistance in bacteria; restriction enzymes as barriers to horizontal gene transfer in Staphylococcus aureus; infectious and bacterial pathogen ...