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  • Chaperones

    Methods and Protocols

    Serier serie Springer Protocols
    This second edition volume expands on the previous edition with new discussions on the latest techniques used to study molecular chaperones and the stress response. The chapters in this book cover such as analysis of the initiation and regulation of the stress response; the role of heat shock protein 90 (Hsp90) in gene expression through chromosome-immunoprecipitation; features of chaperone ... Læs mere

    1.571,11 kr.

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  • RNA Interference (RNAi)

    af Wiley ...
    Serier serie Life Science Research Fundamentals
    The 2006 Nobel Prize in Physiology or Medicine was awarded to Andrew Z. Fire and Craig C. Mello for their discovery of RNA interference (RNAi). RNAi is a biological process in which RNA molecules can silence (inhibit) or up- or down-regulate gene expression, typically by causing the destruction of specific messenger RNA (mRNA) molecules. This collection of articles begins with an introduction to ... Læs mere

    220,49 kr.

  • Antigen Retrieval Immunohistochemistry Based Research and Diagnostics

    Redigeret af Shan-Rong Shi, Clive R. Taylor ...
    Serier Bog 5 - Wiley Series in Biomedical Engineering and Multi-Disciplinary Integrated Systems
    The most complete, up-to-date reference on antigen retrieval and immunohistochemistryAn antigen is a substance that prompts the generation of antibodies and can cause an immune response. The antigen retrieval (AR) technique is in wide use across the globe, and is a critical technique used in medical diagnosis of disease, particularly clinical targeted cancer treatment.Antigen Retrieval ... Læs mere

    1.302,61 kr.

  • Therapeutic Monoclonal Antibodies

    From Bench to Clinic

    Redigeret af Zhiqiang An ...
    70-chapter authoritative reference that covers therapeutic monoclonal antibody discovery, development, and clinical applications while incorporating principles, experimental data, and methodologies.First book to address the discovery and development of antibody therapeutics in their entirety.Most chapters contain experimental data to illustrate the principles described in them.Authors provide ... Læs mere

    1.649,99 kr.

  • Antibody Engineering Volume 1

    Serier serie Springer Protocols
    Antibodies are indispensable tools for research, diagnosis, and therapy. Recombinant approaches allow the modification and improvement of nearly all antibody properties, such as affinity, valency, specificity, stability, serum half-life, effector functions, and immunogenicity. "Antibody Engineering" provides a comprehensive toolbox covering the well-established basics but also many exciting new ... Læs mere

    3.166,13 kr.

  • Antibody Expression and Production

    Redigeret af Mohamed Al-Rubeai ...
    Serier serie Biomedical and Life Sciences (R0)
    Engineered antibodies currently represent over 30% of biopharmaceuticals in clinical trials and their total worldwide sales continue to increase significantly. The importance of antibody applications is reflected in their increasing clinical and industrial applications as well as in the progression of established and emerging production strategies. This volume provides detailed coverage of the ... Læs mere

    1.681,11 kr.

  • Peptides

    Chemistry and Biology

    Thoroughly updated, incorporating around 25 % new material, Sewald/Jakubke remains the only modern and scientifically up-to-date advanced textbook on peptide biochemistry, distilling the knowledge of hundreds of publications into a highly readable synopsis of this diverse field.The authors explain the broad fundamentals of peptide synthesis and structure, systematically addressing important ... Læs mere

    1.189,36 kr.

  • Alternative pre-mRNA Splicing

    Theory and Protocols

    This book was written for graduate and medical students, as well as clinicians and postdoctoral researchers. It describes the theory of alternative pre-mRNA splicing intwelve introductory chapters and then introduces protocols and their theoretical background relevant for experimental research. These 43 practical chapters cover: Basic methods, Detection of splicing events, Analysis of alternative ... Læs mere

    639,24 kr.

  • Current Trends in Monoclonal Antibody Development and Manufacturing

    Serier serie Biomedical and Life Sciences (R0)
    Monoclonal antibodies represent one of the fastest growing areas of new drug development within the pharmaceutical industry. Several blockbuster products have been approved over the past several years including Rituxan, Remicade, Avastin, Humira, and Herceptin. In addition, over 300 new drugs are currently in clinical trials. With both large, established biotechnology companies and small start-ups ... Læs mere

    1.681,11 kr.

  • Antibodies

    Volume 2: Novel Technologies and Therapeutic Use

    Redigeret af G. Subramanian ...
    It is now over one hundred years since von Behring and Kitsato first concluded experiments that led to the use of passive immunisation, employing antibodies raised in animals against tetanus and diphtheria toxins. The advancement of technology both in manufacturing purity product in a cost effective way and the clinical research has proved that antibodies are one ofthe most successful products in ... Læs mere

    840,47 kr.

  • Peptide-based Drug Discovery

    Challenges and New Therapeutics

    Redigeret af Ved Srivastava ...
    Serier Bog 59 - Drug Discovery Series
    With potentially high specificity and low toxicity, biologicals offer promising alternatives to small-molecule drugs. Peptide therapeutics have again become the focus of innovative drug development efforts backed up by a resurgence of venture funds and small biotechnology companies.What does it take to develop a peptide-based medicine? What are the key challenges and how are they overcome? What ... Læs mere

    1.972,95 kr.

  • Phage Display

    Methods and Protocols

    Redigeret af Michael Hust, Theam Soon Lim ...
    Serier serie Springer Protocols
    This second edition details new and updated methods on different antibody libraries, along with novel approaches for antibody discovery. Chapters focuses on the construction of antibody libraries, antibody expression, complementary approaches for antibody selection, and other phage display related applications. Written in the highly successful Methods in Molecular Biology series format, chapters ... Læs mere

    2.045,38 kr.