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  • Cancer Cell Dormancy

    Methods and Protocols

    Redigeret af Marco Montagner ...
    Serier serie Springer Protocols
    This volume provides protocols and techniques to study metastatic dormant cells. Chapters focus on in vitro systems to model metastatic dormancy in vitro, detection of disseminated tumor cells in vivo, perturbation of key molecules involved in metastatic dormancy, and clinical features of delayed metastatic relapses of specific tumor types. Written in the highly successful Methods in Molecular ... Læs mere

    1.484,03 kr.

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  • Culture of Animal Cells

    A Manual of Basic Technique and Specialized Applications

    Since the publication of the sixth edition of this benchmark text, numerous advances in the field have been made – particularly in stem cells, 3D culture, scale-up, STR profiling, and culture of specialized cells. Culture of Animal Cells: A Manual of Basic Technique and Specialized Applications, Seventh Edition is the updated version of this benchmark text, addressing these recent developments in ... Læs mere

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  • The AGT Cytogenetics Laboratory Manual

    Cytogenetics is the study of chromosome morphology, structure, pathology, function, and behavior. The field has evolved to embrace molecular cytogenetic changes, now termed cytogenomics.Cytogeneticists utilize an assortment of procedures to investigate the full complement of chromosomes and/or a targeted region within a specific chromosome in metaphase or interphase. Tools include routine analysis ... Læs mere

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  • Biodegradable Polymers in Clinical Use and Clinical Development

    Redigeret af Abraham J. Domb, Neeraj Kumar ...
    This book focuses on biodegradable polymers that are already in clinical use or under clinical development. Synthetic and natural polymers will be included. This excludes polymers that have been investigated and did not reach clinical development.The purpose of this book is to provide updated status of the polymers that are clinical use and those that are now being developed for clinical use and ... Læs mere

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  • Zebrafish

    Methods and Protocols

    Serier serie Springer Protocols
    This fully updated edition introduces new tools, models, and analytic insights that position the zebrafish even more strongly as an engine of discovery for developmental and disease biology. Beginning with a section exploring detailed methods for use of zebrafish to model a variety of human diseases, the book continues by illuminating the key ongoing role of the fish model in studies of the ... Læs mere

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  • In Vitro Bioassay Techniques for Anticancer Drug Discovery and Development

    This comprehensive and useful handbook represents a definitive up-to-date compendium of key in vitro bioassay methods that are employed to quantify and validate the anticancer activity of a drug candidate before it makes its way in to animal or clinical trials.In Vitro Bioassay Techniques for Anticancer Drug Discovery and Development covers the screening and evaluation of potential drug candidates ... Læs mere

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  • Induced Pluripotent Stem (iPS) Cells

    Methods and Protocols

    Redigeret af Andras Nagy, Kursad Turksen ...
    Serier serie Springer Protocols
    This extensive new edition presents protocols reflecting the great strides made in the study of induced pluripotent stem (iPS) cells. The collection explores new and improved methods for the generation, expansion, and maintenance of iPS cells from different tissue types, characterization of their differentiation pathways along different lineages, and their potential utility in tissue repair and ... Læs mere

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  • Stem Cells and Aging

    Methods and Protocols

    Redigeret af Kursad Turksen ...
    Serier serie Springer Protocols
    This fully updated book collects protocols that reflect current investigations into how stem cell populations change during organismal aging. These methodologies are well-established and described in easy-to-follow fashion so as to be valuable for not only experts but also novices in this ever-developing area of stem cell research. Written for the highly successful Methods in Molecular Biology ... Læs mere

    1.587,91 kr.

  • Hepatocytes

    Methods and Protocols

    Redigeret af Naoki Tanimizu ...
    Serier serie Springer Protocols
    This volume details experimental protocols to study structure and function of hepatocytes in vivo and in vitro, and for characterizing heterogeneity and plasticity of hepatocytes in healthy and in injured liver. Chapters guide readers through separating hepatocyte subfractions, characterizing the heterogeneity, novel culture systems, hepatocyte-like cells from human pluripotent stem cells, ... Læs mere

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  • Induced Pluripotent Stem Cells and Human Disease

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    Redigeret af Kursad Turksen ...
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    This detailed volume presents a series of protocols that are representative of recent developments and improvements in induced pluripotent stem cells (iPS cells) and corresponding human disease models. Reflecting the latest technology for generating induced pluripotent stem cells (iPS cells) and their initial characterization, the book explores techniques invaluable both for studies of disease ... Læs mere

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  • Tumor Angiogenesis Assays

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    Redigeret af Domenico Ribatti ...
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    This second edition provides new and updated methods and protocols for studying tumor angiogenesis in vitro and in vivo. Chapters detail morphological aspects of tumor angiogenesis, aortic ring, ex vivo tissue culture model for anti-angiogenic drug testing, transgenic zebrafish, orthotopic models of ovarian cancer, and uncovering metabolic effects of anti-angiogenic therapy in tumors by induced ... Læs mere

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  • Regulatory T-Cells

    Methods and Protocols

    Redigeret af Masahiro Ono ...
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    This volume provides methods and models for investigating the immunosuppressive subset of CD4+ T-cells, regulatory T-cells (Treg). Chapters guide readers through, basic protocols for analyzing Treg in mice and humans, single-cell analysis for analyzing Treg, and methods for the analysis of Treg in clinical application. Written in the format of the highly successful Methods in Molecular Biology ... Læs mere

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