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  • Lymphoma

    Methods and Protocols

    Redigeret af Ralf Küppers ...
    Serier serie Springer Protocols
    This detailed volume expands upon the previous edition with key methods currently used in lymphoma research, partly specific for lymphoma research but often adaptable to the study of other cancers. New chapters explore the latest approaches for single cell B cell and T cell receptor sequencing, multiplexed immunophenotyping of lymphoma tissue samples, genetic manipulation and extended culture of ... Læs mere

    2.093,11 kr.

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  • Antigen Retrieval Immunohistochemistry Based Research and Diagnostics

    Redigeret af Shan-Rong Shi, Clive R. Taylor ...
    Serier Bog 5 - Wiley Series in Biomedical Engineering and Multi-Disciplinary Integrated Systems
    The most complete, up-to-date reference on antigen retrieval and immunohistochemistryAn antigen is a substance that prompts the generation of antibodies and can cause an immune response. The antigen retrieval (AR) technique is in wide use across the globe, and is a critical technique used in medical diagnosis of disease, particularly clinical targeted cancer treatment.Antigen Retrieval ... Læs mere

    1.302,61 kr.

  • Translational Medicine

    Molecular Pharmacology and Drug Discovery

    Redigeret af Robert A. Meyers ...
    Serier serie Advances in Molecular Biology and Medicine
    This reference work gives a compete overview of the different stages of drug development using a translational approach. The book is structured in different parts, following the different stages in drug development. Almost half of the work is dedicated to core of drug discovery using a translational approach, the identification of appropriate targets and screening methods for the identification of ... Læs mere

    2.535,24 kr.

  • Platelet Proteomics

    Principles, Analysis, and Applications

    Serier Bog 47 - Wiley Series on Mass Spectrometry
    The purpose of the book is to introduce platelets, and their functional role in thrombotic and cardiovascular disease, justifying the relevance of platelet proteomics research. Focus then shifts to the recent developments on mass spectrometry (MS)-based proteomics. This chapter shows potential applications for platelet proteomics not yet carried out. It includes examples of post-translational ... Læs mere

    758,11 kr.

  • Antibody Engineering Volume 1

    Serier serie Springer Protocols
    Antibodies are indispensable tools for research, diagnosis, and therapy. Recombinant approaches allow the modification and improvement of nearly all antibody properties, such as affinity, valency, specificity, stability, serum half-life, effector functions, and immunogenicity. "Antibody Engineering" provides a comprehensive toolbox covering the well-established basics but also many exciting new ... Læs mere

    3.166,13 kr.

  • Antibody Expression and Production

    Redigeret af Mohamed Al-Rubeai ...
    Serier serie Biomedical and Life Sciences (R0)
    Engineered antibodies currently represent over 30% of biopharmaceuticals in clinical trials and their total worldwide sales continue to increase significantly. The importance of antibody applications is reflected in their increasing clinical and industrial applications as well as in the progression of established and emerging production strategies. This volume provides detailed coverage of the ... Læs mere

    1.681,11 kr.

  • IMMUNO-model in Cancer

    Methods and Protocols

    Redigeret af Sweta Rani, Lukasz Skalniak ...
    Serier serie Springer Protocols
    This open access volume describes the computational and experimental models that help researchers understand the responses of the immune system in cancer and test experimental immune-oncology approaches. The chapters in this book cover methods such as profile polarization in macrophages using ELISA; immune checkpoint inhibitors; interactions of PD-1/PD-L1 and T cells; immunocompetent preclinical ... Læs mere

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  • Current Trends in Monoclonal Antibody Development and Manufacturing

    Serier serie Biomedical and Life Sciences (R0)
    Monoclonal antibodies represent one of the fastest growing areas of new drug development within the pharmaceutical industry. Several blockbuster products have been approved over the past several years including Rituxan, Remicade, Avastin, Humira, and Herceptin. In addition, over 300 new drugs are currently in clinical trials. With both large, established biotechnology companies and small start-ups ... Læs mere

    1.681,11 kr.

  • Antibody Drug Discovery

    af Clive R Wood ...
    Serier Bog 4 - Molecular Medicine And Medicinal Chemistry
    Monoclonal antibodies have become important treatments for cancer, inflammation and a wide range of other diseases, representing an increasing share of the most successful pharmaceutical markets. The technologies to discover these drugs have been developed by select centers of excellence in industry and academia, and are continually being fine tuned in the race to identify the best antibody-based ... Læs mere

    445,74 kr.

  • Protein Therapeutics

    Serier serie Methods & Principles in Medicinal Chemistry
    In this practice-oriented two volume handbook, professionals from some of the largest biopharmaceutical companies and top academic researchers address the key concepts and challenges in the development of protein pharmaceuticals for medicinal chemists and drug developers of all trades.Following an introduction tracing the rapid development of the protein therapeutics market over the last decade, ... Læs mere

    1.997,61 kr.

  • T-Cell Development

    Methods and Protocols

    Redigeret af Remy Bosselut, Melanie S. Vacchio ...
    Serier serie Springer Protocols
    This second edition volume provides new and updated chapters detailing simple and accessible experiment protocols to explore thymus biology. Chapters are divided into three parts presenting short reviews, analysis strategies, protocols for cell preparation, flow cytometry analyses, Innate Lymphoid Cells (ILC), mouse T-cell development, antigen receptor-less cousins of T cells, bone marrow chimeras ... Læs mere

    1.260,86 kr.

  • Immunoproteomics

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    Redigeret af Kelly M. Fulton, Susan M. Twine ...
    Serier serie Springer Protocols
    This third edition volume expands on the previous editions with new chapters discussing advancements in mass spectrometry resolution, sensitivity, and speed, including the refinement of the identification of peptides presented on the surface of major histocompatibility proteins. These technologies continue to advance vaccine development, as well as cancer immunotherapy and precision medicine. ... Læs mere

    1.681,04 kr.