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  • MicroRNA Profiling

    Methods and Protocols

    Redigeret af Sweta Rani ...
    Serier serie Springer Protocols
    This second edition provides updated and comprehensive methods on miRNA biogenesis and their role in the development and progression of various human diseases. Chapters detail miRNA biogenesis, isolating RNA, extracellular vesicles (EVs), circulating miRNAs, analyzing miRNA and miRDeep-P2, protocols for total RNA isolation from cells, cell-derived products, isolation and characterization of ... Læs mere

    1.021,24 kr.

  • IMMUNO-model in Cancer

    Methods and Protocols

    Redigeret af Sweta Rani, Lukasz Skalniak ...
    Serier serie Springer Protocols
    This open access volume describes the computational and experimental models that help researchers understand the responses of the immune system in cancer and test experimental immune-oncology approaches. The chapters in this book cover methods such as profile polarization in macrophages using ELISA; immune checkpoint inhibitors; interactions of PD-1/PD-L1 and T cells; immunocompetent preclinical ... Læs mere

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  • B-Cell Receptor Signaling

    Methods and Protocols

    Redigeret af Palash Chandra Maity ...
    Serier serie Springer Protocols
    B-lymphocytes produce antibodies, mediate humoral responses, and act as a key to the adaptive immune system of our body. The development and function of B cells are largely dependent on B cell antigen receptors (BCRs), which transmit a multitude of signals upon binding to the cognate antigen and activate the survival, proliferation, and differentiation of B cells thereof. Thus, studying the BCR ... Læs mere

    1.924,99 kr.

  • Cancer Immunosurveillance

    Methods and Protocols

    Serier serie Springer Protocols
    This new edition explores the innovation and improvement of experimental techniques harnessed to dissect the complex relationship between cancer cells and the immune system of the host. Beginning with spectral and multicolor flow cytometric methods to characterize the immune contexture of different forms of metastases, the book continues with functional assays to study the activation status of ... Læs mere

    1.681,11 kr.

  • Cancer Systems and Integrative Biology

    Redigeret af Usha N. Kasid, Robert Clarke ...
    Serier serie Springer Protocols
    This thorough volume explores recent advances that have revolutionized the field of precision oncology. The chapters, contributed by experts in the areas of cancer systems and integrative biology, provide hands-on guidance toward developing tools to monitor spatial and temporal changes in tumors, tracking tumor markers in blood, and ultimately developing precision medicine to combat cancer in real ... Læs mere

    1.494,25 kr.

  • Gene, Drug, and Tissue Engineering

    Redigeret af Glaucia C. Pereira ...
    Serier serie Springer Protocols
    This book combines discursive chapters that present the latest progress in molecular biology, drug discovery, organ-tissue engineering, and related fields, with a number of descriptive chapters on methods, protocols, and case studies. Structured into four parts, this volume walks the reader through the latest in cellular biology, with discussions on novel medicinal plant metabolites, ... Læs mere

    1.260,86 kr.

  • Cancer Cytogenetics and Cytogenomics

    Methods and Protocols

    Redigeret af Jing Christine Ye, Henry H. Heng ...
    Serier serie Springer Protocols
    This detailed volume explores the frontiers of this new era in cancer cytogenetics and cytogenomics, focusing on establishing a karyotype as an information-based genomic framework, as well as presenting technological platforms for collecting and analyzing data at the genome level. It begins with several conceptual chapters that introduce ideas such as the Genome Architecture Theory, forcefully ... Læs mere

    1.092,74 kr.

  • Immunoproteomics

    Methods and Protocols

    Redigeret af Kelly M. Fulton, Susan M. Twine ...
    Serier serie Springer Protocols
    This third edition volume expands on the previous editions with new chapters discussing advancements in mass spectrometry resolution, sensitivity, and speed, including the refinement of the identification of peptides presented on the surface of major histocompatibility proteins. These technologies continue to advance vaccine development, as well as cancer immunotherapy and precision medicine. ... Læs mere

    1.681,04 kr.

  • Cancer Drug Resistance

    Methods and Protocols

    Redigeret af Marta Baiocchi ...
    Serier serie Springer Protocols
    This volume discusses the latest techniques used to identify cancer drug resistance determinants at the molecular, cellular, and functional levels. Chapters in this book cover up-to-date topics including tumor-microenvironment cell co-culture methods and microfluidics systems; workflows for functional assessment of drug resistance in vitro and in vivo; quantitative techniques for identifying ... Læs mere

    1.008,61 kr.

  • Regulatory T-Cells

    Methods and Protocols

    Redigeret af Masahiro Ono ...
    Serier serie Springer Protocols
    This volume provides methods and models for investigating the immunosuppressive subset of CD4+ T-cells, regulatory T-cells (Treg). Chapters guide readers through, basic protocols for analyzing Treg in mice and humans, single-cell analysis for analyzing Treg, and methods for the analysis of Treg in clinical application. Written in the format of the highly successful Methods in Molecular Biology ... Læs mere

    840,49 kr.

  • FOXO Transcription Factors

    Methods and Protocols

    Redigeret af Wolfgang Link ...
    Serier serie Springer Protocols
    This second edition volume expands on the previous edition with updates on the latest techniques and technologies used in FOXO research. The chapters in this book are organized into five parts. Part One covers biochemical techniques used to analyze phosphorylation status of FOXO proteins, identify FOXO binding partners, and assess FOXO-specific transcriptional activity. Part Two highlights genetic ... Læs mere

    2.138,77 kr.

  • Target Identification and Validation in Drug Discovery

    Methods and Protocols

    Redigeret af Jürgen Moll, Sebastian Carotta ...
    Serier serie Springer Protocols
    This third edition book explores breakthrough techniques in the field of drug target identification and validation. With technologies and methodologies ranging from target identification to the analysis of clinical samples, as well as newer areas like artificial intelligence and machine learning applications, the book will aid decision-makers in drug development by offering a succinct overview of ... Læs mere

    1.428,99 kr.