The accurate diagnosis of haematologic malignancies is a complex and challenging task. It routinely involves morphologic, molecular, cytogenetic and flow cytometric expertise. To determine what treatment protocol will be followed, it is vital to integrate, interpret and report these results accurately.Flow cytometry is key in this diagnostic pathway.This book guides the reader as to how flow cytometry results should be interpreted and applied to optimize patient care. At th...

The analysis of blood, bone marrow and tissue fluid specimens requires a multi-faceted approach with the integration of scientific data from a number of disciplines. No single discipline can operate in isolation or errors will occur. Flow cytometry is in a privileged position in that it can provide rapid analysis of specimens and it is often the first definitive investigation to produce results and help formulate a working diagnosis.This companion text to Practical Flow Cytomet...

This comprehensive volume discusses the protease ADAMTS13, summarizing the current status of basic and clinical research. The nine authoritative chapters begin with a historical perspective followed by exploration of the biochemistry and structure-function relationships of ADAMTS13 as well as its normal function in hemostasis (cleavage of von Willebrand factor). Emerging research themes for ADAMTS13 are covered, including its potential role in angiogenesis and other aspects of cell biology...

Neonatal hematology is a fast-growing field, and hematologic problems occur in the majority of sick neonates. Focusing on clinical issues and problem-solving, this is a fully revised and updated revision of a successful practical guide to the pathogenesis, recognition and management of hematologic problems in the neonate. The second edition begins with chapters on the history of neonatal hematology, hematopoiesis, and the immunologic system. Subsequent sections are devoted to erythrocyte d...

The Blood Group Antigen FactsBook — winner of a 2013 Highly Commended BMA Medical Book Award for Internal Medicine — has been an essential resource in the hematology, transfusion and immunogenetics fields since its first publication in the late 1990s.The third edition of The Blood Group Antigen FactsBook has been completely revised, updated and expanded to cover all 33 blood group systems. It blends scientific background and clinical applications and provides busy researchers and clinician...

The second edition of Essential Guide to Blood Groups is a pocket-sized book containing four-color text together with schematic figures and tables. The book comprises an introduction to blood groups, followed by chapters on techniques, information on various blood groups, antibodies, quality assurance in immunohaematology, and it concludes with chapters on troubleshooting in the laboratory, and FAQs. It also covers the serology, inheritance, biochemistry and molecular genetics of ...

A fully-updated edition of the ultimate haematology textbook for diagnostic use Microscopic Haematology, 3rd Edition: A practical guide for the laboratory has been fully updated in line with the current World Health Organisation classification. In addition to providing a wealth of information on haematology, this excellent textbook for health professionals includes over 400 full colour haematological slides. Microscopic Haematology, 3rd Edition: A practical guide for the laboratory is arra...

This issue of Hematology/Oncology Clinics is edited by Dr. Jennifer Brown and focuses on Chronic Lymphocytic Leukemia. Article topics include: What Have Recent Genomic Advances Taught us About CLL?, Biology of CLL in Different Microenvironments,What is the Significance of Stereotyped BCRs in CLL?, Understanding Immunodeficiency in CLL, MBL vs CLL: How Important is the Distinction?, Risk Stratification of CLL in 2012, Minimal Residual Disease Measurement in CLL, The BTK Inhibitor PCI-32765 ...

Variant Haemoglobins – A Guide to Identification is based on the premise that any single diagnostic technique offers only a very provisional identification of a variant haemoglobin. In routine diagnostic practice two techniques are needed as a minimum, with the results being interpreted in the light of the clinical details, blood count, blood film and ethnic origin. This book covers 150 normal and variant haemoglobins that have been studied and carefully documented.Var...

This is an essential guide to the data, basic science, outcome studies and decision-making processes involved in blood and marrow stem cell transplantation. Organized according to disease types and procedures, it contains more than 100 tables, figures and algorithms that reflect up-to-date research and give guidance on the choices between different types of chemotherapy, autologous vs. allogeneic transplantation, peripheral blood vs. bone marrow stem cells, and standard vs. experimental tr...

This book is a full-color atlas of both benign and neoplastic proliferations in the blood. It illustrates the morphologic features on peripheral blood smears of the various disorders, and the text will focus on diagnostic criteria, differential diagnosis, and modern classification terminology. The book may be used as a stand-alone resource and should be useful to trainees and clinicians that routinely review peripheral blood smears. The accompanying on-line site contains the full text and ...