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  • The Use of Hypomethylating Agents As A Therapeutic Against DNA Hypermethylation In ccRCC

    A mock grant proposal for the National Institutes of Health written by Amirali Banani

    par Amirali Banani ...
    Many research studies have demonstrated that DNA hypermethylation is linked to the development of clear cell renal cell carcinomas (ccRCC) by the transcriptional silencing of important tumor suppressor genes known as Von Hippel-Lindau (VHL). The results of these studies led me to ask the question, “could hypomethylating agents be used to demethylate the hypermethylated H3K4me1 marks of VHL tumor ... En savoir plus

    Gratuit

  • I Contain Multitudes

    The Microbes Within Us and a Grander View of Life

    par Ed Yong ...
    New York Times BestsellerNew York Times Notable Book of 2016 • NPR Great Read of 2016 • Named a Best Book of 2016 by The Economist, Smithsonian, NPR's Science Friday, MPR, Minnesota Star Tribune, Kirkus Reviews, Publishers Weekly, The Guardian, Times (London)From Pulitzer Prize winner Ed Yong, a groundbreaking,... ... En savoir plus

    10,57 €

  • Extremes

    Life, Death and the Limits of the Human Body

    par Kevin Fong ...
    In anaesthetist Dr Kevin Fong's television programmes he has often demonstrated the impact of extremes on the human body by using his own body as a 'guinea pig'. So Dr Fong is well placed to share his experience of the sheer audacity of medical practice at extreme physiological limits, where human life is balanced on a knife edge. Through gripping accounts of extraordinary events and pioneering ... En savoir plus

    3,99 €

  • Bitten

    The Secret History of Lyme Disease and Biological Weapons

    par Kris Newby ...
    A riveting thriller reminiscent of The Hot Zone, this true story dives into the mystery surrounding one of the most controversial and misdiagnosed conditions of our time—Lyme disease—and of Willy Burgdorfer, the man who discovered the microbe behind it, revealing his secret role in developing bug-borne biological weapons, and raising terrifying questions about the genesis of the epidemic of tick ... En savoir plus

    10,99 €

  • Bad Science

    par Ben Goldacre ...
    Ben Goldacre’s wise and witty bestseller, shortlisted for the Samuel Johnson Prize, lifts the lid on quack doctors, flaky statistics, scaremongering journalists and evil pharmaceutical corporations.Since 2003 Dr Ben Goldacre has been exposing dodgy medical data in his popular Guardian column. In this eye-opening book he takes on the MMR hoax and misleading cosmetics ads, acupuncture and homeopathy ... En savoir plus

    7,79 €

  • Dopamine Nation

    Why our Addiction to Pleasure is Causing us Pain

    par Dr Anna Lembke ...
    THE MILLION COPY INTERNATIONAL BESTSELLERWe are a wired generation. In these fast-paced times we are constantly bombarded by high-reward, high-dopamine stimuli. From texting to social media, food to drugs, gambling to shopping, we have become addicted to fleeting and distracting pleasures that are making us sick.In Dopamine Nation*,* psychiatrist and bestselling author Dr Anna Lembke reveals why ... En savoir plus

    6,99 €

  • The Definitive Guide to the Perimenopause and Menopause

    The Sunday Times bestseller 2024

    'Louise is a voice you can really trust. I've learnt so much from her and now you can too.' - Holly Willoughby 'Dr Louise is a miracle worker' - Lorraine Kelly 'Louise is my No. 1 go-to when it comes to anything menopause and this book is perfect for when I'm worried about anything.'- Alison Hammond 'Louise Newson is wonderful... a real expert in her field.' - Joe WicksYour complete, expert, ... En savoir plus

    12,99 €

  • Managing your Mental Health during your PhD

    A Survival Guide

    par Zoë J. Ayres ...
    Collection series Biomedical and Life Sciences (R0)
    This book explores the PhD experience as never before and provides a “survival guide” for current and prospective PhD students. The book investigates why mental health issues are so common among the postgraduate population, going beyond the statistics, looking at lived experience of both the author and as well as current PhD students, who have found balancing mental wellness with the PhD endeavour ... En savoir plus

    23,16 €

  • Perspectives on Fluorescence

    A Tribute to Gregorio Weber

    Modifié par David M. Jameson ...
    Collection series Chemistry and Material Science (R0)
    Gregorio Weber is widely acknowledged as the person responsible for the advent of modern fluorescence spectroscopy. Since 2016 is the 100th anniversary of Gregorio Weber’s birth, this special volume has been prepared to honor his life and achievements. It offers contributions from outstanding researchers in the fluorescence field, describing their perspectives on modern fluorescence and its highly ... En savoir plus

    185,39 €

  • RNA and DNA Diagnostics

    Collection series Biomedical and Life Sciences (R0)
    The aim of molecular diagnostics is preferentially to detect a developing disease before any symptoms appear. There has been a significant increase, fueled by technologies from the human genome project, in the availability of nucleic acid sequence information for all living organisms including bacteria and viruses. When combined with a different type of instrumentation applied, the resulting ... En savoir plus

    83,42 €

  • Doing Conversation, Discourse and Document Analysis

    par Tim Rapley ...
    Collection series Qualitative Research Kit
    Introducing the theory and practice of conversation, discourse and document analysis, this book proves how useful these methods are in addressing key questions in the social sciences. A true masterclass on practical issues such as generating an archive, transcribing video material, and analyzing discourses using a full range of documentary and verbal data. It is the essential guide to exploring ... En savoir plus

    59,73 €

  • Molecular Diagnostics

    Part 1: Technical Backgrounds and Quality Aspects

    The books Molecular Diagnostics Part 1 and 2 provide a comprehensive and practical overview of the state-of-the-art molecular biological diagnostic strategies that are being used in a wide variety of disciplines.The editors and experts in their respective fields have combined their knowledge to write these two books. Many years of experience in the development, application and quality control of ... En savoir plus

    120,50 €

  • Brain Organoids in Research and Therapy

    Fundamental Ethical and Legal Aspects

    Collection series Medicine (R0)
    This volume elucidates the pivotal ethical and legal issues arising from the use of brain organoids for research, therapeutic and enhancement purposes.The function of the human brain is still a mystery. Until recently, only post-mortem tissue was available for a structural examination of the brain. Consequently, the examination results could only reflect the state at the end of life. However, in ... En savoir plus

    92,69 €

  • Co-Producing and Co-Designing

    Collection series Elements of Improving Quality and Safety in Healthcare
    Many healthcare improvement approaches originated in manufacturing, where end users are framed as consumers. But in healthcare, greater recognition of the complexity of relationships between patients, staff, and services (beyond a provider-consumer exchange) is generating new insights and approaches to healthcare improvement informed directly by patient and staff experience. Co-production sees ... En savoir plus

    17,81 €

  • Human Challenge Studies for Vaccine Development

    Collection series Biomedical and Life Sciences (R0)
    This volume offers insights into human challenge studies, where adult volunteers are deliberately infected with a pathogen of interest. These studies can broaden our knowledge on infections that have a rather low natural infection rate, but still bear a great threat to global health. The authors also present instances, where no suitable animal model is available to help understand human immune ... En savoir plus

    185,39 €

  • The EuroQol Group after 25 years

    par Richard Brooks ...
    Collection series Biomedical and Life Sciences (R0)
    The EuroQol Group first met in Rotterdam in May 1987 determined to develop a standardised non-disease-specific instrument for valuing health-related quality of life. The book traces the activities of the Group over the next 25 years. The instrument constructed, eventually named the EQ-5D, was translated into many languages and used in a wide range of countries and settings. The book describes how ... En savoir plus

    129,77 €

  • Aptamers

    Biotechnological Applications of a Next Generation Tool

    Collection series Biomedical and Life Sciences (R0)
    The book discusses the basics of aptamers and the advent of aptamer-based technology in recent times. The book covers the diverse applications of aptamers, such as in detection of animal and plant pathogens, disease diagnosis and therapeutics, environmental contamination detection etc. Besides these applications, the book also describes the use of these synthetic or modified DNA, as drug delivery ... En savoir plus

    83,42 €

  • Research Regulatory Compliance

    Modifié par Mark A. Suckow, Bill Yates ...
    Research Regulatory Compliance offers the latest information on regulations and compliance in the laboratory. With the increasing complexity of regulations and need for institutional infrastructure to deal with compliance of animal use issues, as well as a requirement surrounding human subjects, this publication provides reputable guidance and information. The book is extremely helpful as a ... En savoir plus

    63,85 €

  • The Skin and Gene Therapy

    Collection series Medicine (R0)

    46,34 €

  • Life and Hope

    The Impact of Organ Transplantation on the Human Experience

    par Mark A. Greene ...
    At the age of eleven, Mark Greene nearly died. Neither he nor his parents knew that Mark suffered from end stage renal disease; he would need a kidney transplant to survive. Now, more than twenty-six years after his successful transplant operation, Greene tells the story of his survival following that operation.Currently, there are approximately 170,000 organ transplant recipients in the United ... En savoir plus

    8,44 €

  • Molecular Approaches to Heart Failure Therapy

    Modifié par G. Hasenfuss, E. Marban ...
    G. HASENFUSS, E. MARBAN Heart failure embodies the central irony of modern medicine. As we have become increasingly adept at treating the major proximate causes of death in Western society, we have effectively converted acute illness into chronic malady. The last twenty years have witnessed a revolution in the treatment of acute coronary syndromes, myocardial infarction in particular. Patients who ... En savoir plus

    83,42 €

  • Cognitive Enhancement

    An Interdisciplinary Perspective

    Collection series Biomedical and Life Sciences (R0)
    Cognitive enhancement is the use of drugs, biotechnological strategies or other means by healthy individuals aiming at the improvement of cognitive functions such as vigilance, concentration or memory without any medical need. In particular, the use of pharmacological substances (caffeine, prescription drugs or illicit drugs) has received considerable attention during the last few years. Currently ... En savoir plus

    129,77 €

  • Light Pollution as a New Risk Factor for Human Breast and Prostate Cancers

    Collection series Biomedical and Life Sciences (R0)
    Humans are diurnal organisms whose biological clock and temporal organization depend on natural light/dark cycles. Changes in the photoperiod are a signal for seasonal acclimatization of physiological and immune systems as well as behavioral patterns. The invention of electrical light bulbs created more opportunities for work and leisure. However, exposure to artificial light at night (LAN) ... En savoir plus

    129,77 €