Recent advances in single molecule science have presented a new branch of science: single molecule cellular biophysics, combining classical cell biology with cutting-edge single molecule biophysics. This textbook explains the essential elements of this new discipline, from the state-of-the-art single molecule techniques to real-world applications in unravelling the inner workings of the cell. Every effort has been made to ensure the text can be easily understood by students from both the p...

A BBC Radio 3 dramatisation of Vikram Seth's verse novel about the lives and loves of a group of twentysomethings in 1980s San FranciscoAward-winning novelist Vikram Seth is renowned worldwide for his magnum opus A Suitable Boy. But his dazzling debut, though less well-known, is equally innovative, masterly and ambitious. First published in 1986. and inspired by Pushkin's Eugene Onegin, it is written entirely in verse, comprising almost 600 stanza...

Biophysics: Tools and Techniques for the Physics of Life covers the experimental, theoretical, and computational tools and techniques of biophysics. It addresses the purpose, science, and application of all physical science instrumentation, theoretical analysis, and biophysical computational methods used in current research labs.The book first presents the historical background, concepts, and motivation for using a physical science toolbox to understand biology. It...

This detailed new edition collects cutting-edge laboratory protocols, techniques, and applications in use by some of the leading international experts in the broad field of chromosome architecture. The book emphasizes the increasing physiological relevance of chromosome architecture investigation, manifest both through application of more complex bottom-up assays in vitro as well as through maintaining the native physiological context through the investigation of living, functiona...

This book describes modern biophysical techniques that enable us to understand and examine dynamic processes of infection at the molecular level. Cutting-edge research articles, laboratory protocols, case studies and up-to-date reviews cover topics such as single-molecule observation of DNA replication repair pathways in E. coli; evolution of drug resistance in bacteria; restriction enzymes as barriers to horizontal gene transfer in Staphylococcus aureus; infectious and bacterial pathogen ...