An integrated presentation of the basic science and clinical applications of anticancer agentsAimed at both undergraduate and postgraduate readers, this unique text provides readers with a fully-integrated presentation of all aspects of the science of anticancer drugs, including their chemistry, pharmacology, and clinical applications.After heart disease, cancer is the number one killer worldwide, and the tumor microenvironment is forever changing, creating...

An Integrated Guide to Human Drug Metabolism: From Basic Chemical Transformations to Drug-Drug Interactions uses the chemistry of each of the metabolic transformations to underpin the discussion of drug interactions with foods, herbal medicines and other drugs. Each of the human metabolic processes will be covered, employing examples drawn from known metabolic transformations of drugs used clinically. The clinical relevance of metabolism is discussed, focusing on appropriate prescribing (a...

Antibacterial agents act against bacterial infection either by killing the bacterium or by arresting its growth. They do this by targeting bacterial DNA and its associated processes, attacking bacterial metabolic processes including protein synthesis, or interfering with bacterial cell wall synthesis and function.Antibacterial Agents is an essential guide to this important class of chemotherapeutic drugs. Compounds are organised according to their target, which helps the r...

There's nothing more mysterious than a locked box. Whether it's a literal strongbox, an empty coffin, the inner workings of a scientist's mind, or an underground prison cell, there are those who will use any means necessary to unlock the secrets of The Mystery Box.With this anthology, bestselling author Brad Meltzer introduces twenty-one original stories from today's most prominent mystery writers. In Laura Lippman's "Waco 1982," a young reporter stuck with a seemingly mun...

"The day I saw you seeing me that was the first time I could see the truth that I was loved completely."In Only the Lover Sings, book and album one of The Well Trilogy, the face to face encounter between Jesus and the woman at the well sets the stage for this series of songs and essays from an array of contributors. Only the Lover Sings explores the ways God is inviting every one of us to bravely turn towards Jesus and be surprised by the...

A look back at how powerful politicians, business leaders, and a diverse cast of activists used a thwarted Olympics to shape the state of Colorado and the city of Denver.If you don’t recall the 1976 Denver Olympic Games, it’s because they never happened. The Mile-High City won the right to host the winter games and then was forced by Colorado citizens to back away from its successful Olympic bid through a statewide ballot initiative. Adam Berg details the powerful ...

From popular copycat recipe developer and bestselling author Todd Wilbur comes a brand-new book of favorite dishes readers can recreate right in their own homes—and learn the secrets to creating delicious dupes of their own!America’s #1 food hacker is here to help anyone looking to recreate their favorite drinks, dishes, and desserts right at home. Todd Wilbur is a one-man culinary cover band who identifies and decodes America’s favorite restaurant dishes and belov...

For those inspired by Barclay's Paul and the Gift Over the course of his academic career, John M. G. Barclay has transformed how we think about Paul. Barclay's contributions to Pauline Studies reached a new height with the publication of his award-winning Paul and the Gift, in which he presents a sophisticated reading of Paul's theology of grace within the context of gift-giving in the Greco-Roman world. But where does Pauline scholarship go from her...

The twelve essays in A Critical Companion to Mel Gibson offer various interpretations of Mel Gibson’s work, treating this prolific but controversial figure not only as a filmmaker but as a historian, religious thinker, and social philosopher. From The Man Without a Face and Braveheart to The Passion of the Christ, Apocalypto, and Hacksaw Ridge, this interdisciplinary collection mines Gibson’s life and oeuvre for insight into existential...

John Engler, former Governor of Michigan, once claimed that redistricting is one of the purest actions a legislative body can take. Academicians and political leaders alike, however, have regularly debated the ideal way by to redistrict national and state legislatures. Rather than being the pure process that Governor Engler envisioned, redistricting has led to repeated court battles waged on such traditional democratic values as one person, one vote, and minority rights. Instead of being a...

The purpose of Communicating in the Anthropocene: Intimate Relations is to tell a different story about the world. Humans, especially those raised in Western traditions, have long told stories about themselves as individual protagonists who act with varying degrees of free will against a background of mute supporting characters and inert landscapes. Humans can be either saviors or destroyers, but our actions are explained and judged again and again as emanating from the individual. And yet...

Warlock's Play: 550+ Supernatural Mysteries, Macabre & Horror Classics' is an unparalleled anthology that casts a wide net across the shadowy waters of supernatural literature, pulling from the depths a staggering array of narratives that have shaped the horror and gothic genres. This collection boasts an eclectic mix of styles and forms, ranging from Victorian ghost stories to eerie folk tales and psychological thrillers, encapsulating the development of horror literature from its incepti...