One person in four in the industrialized countries suffers from hyperuricemia and is therefore at risk of developing gouty arthritis, nephrolithiasis, or any of the other consequences of urate deposition. At present, far too little is known about urate deposition and the mechanisms by which it occurs, as well as about its clinical consequences, which include formation of toph; over the helix of the ear or in bones close to joints that have never exhibited an attack, development of bursitis...

The prevalence of hypertension is almost three times as high as that of diabetes mellitus type 2, with both conditions being major risk factors for stroke, ischemic heart disease, cardiac arrhythmias, and heart failure. The exact prevalence of hypertension related to hormonal derangements (endocrine hypertension) is not known but estimated to affect less than 15% of hypertensive patients. Recent scientific discoveries have increased the understanding of the pathophysiologic mechanisms of h...

The Textbook of Nephro-Endocrinology is the definitive translational reference in the field of nephro-endocrinology, investigating both the endocrine functions of the kidneys and how the kidney acts as a target for hormones from other organ systems. It offers researchers and clinicians expert, gold-standard analyses of nephro-endocrine research and translation into the treatment of diseases such as anemia, chronic kidney disease (CKD), rickets, osteoporosis, and, hypoparathyroidism. - Inve...

Bone densitometry (BD) is an extraordinary clinical tool. It provides a safe, non-invasive window to the skeleton. Through that window, a physician can obtain vital clinical information that enhances diagnosis and improves patient management. Further, much has changed in the last decade to make bone densitometry the especially fascinating field of medicine it is today, incorporating imaging, physics, quantitative analysis, statistics, and computer technology -- all applied in the diagnosis...

This timely volume provides an overview to the causes, effects on systems and clinical approaches of metabolic acidosis. Beginning with a basic understanding of the physiology, pathophysiology and development of this disease, subsequent chapters cover the characteristics and context of the processes that can cause it and a thorough presentation of management strategies. Recommended treatments include those carried out by the health care provider as well as the individual patient, such as d...

- Brings together up-to-date bone and mineral metabolism methods in one easily, accessible volume - Provides a quick reference for bone and mineral disorders - Addresses problems likely to be seen at all ages, from the pre-term infant to the centenarian - Ideal for practicing physicians, residents, medical students, and researchers

The ciliopathies are a group of rare diseases that often affect multiple systems within the body, and are caused by defects in the function or structure of cilia. When cilia go wrong, there are profound consequences; these are discussed in detail for the first time in Ciliopathies: a reference for clinicians. The book provides a clinical overview and reference to this newly emergent group of disorders ranging from Alström syndrome to putative ciliopathic disorders. Each chapter pr...

This book presents a comprehensive and instructive management plan for physicians who care for CKD patients. Basic aspects of CKD, clinical assessment, evaluation and management of risk factors, cardiovascular disease in the context of CKD, assessment and management of CKD complications, special circumstances in CKD patients, and the path to renal replacement therapy are all thoroughly covered. Diagnostic and therapeutic approaches are presented according to the latest staging system for C...

For practitioners at all stages of experience, diseases of the parathyroid glands are not easily deciphered. There are many subtleties to its pathology and diagnosis. Today, the wealth of new information from molecular medicine makes it very challenging for the individual practitioner to have a complete picture of these entities. Diseases of the Parathyroid Glands addresses these issues by offering a concise, user-friendly text that provides state-of-the-art background on mineral ...

An overview of the diagnosis, treatment, and long-term management of diabetic-related kidney disease in clinical practice. Includes an evidence-based discussion of currently available and experimental drug therapies currently in development, guided by international consensus guidelines. Ideal for physicians, medical trainees, nurses and other medical professional that regularly screen and treat patients with all types of diabetes.

In many ways this book is a team effort. Many people havc helped me in writing it. Firstly, I thank my wife who read the manu script twice correcting grammatical errors and spelling and clarifying many sentences. Secondly, I thank friends and co- leagues at St. Mary's Hospital, including Mrs Jean Emerson, Renal Unit Social Worker and Mrs June Morgan, Senior Dietician, both of whom cOlltributed technical information; Si sters Christine Holmes and Malinie Polpitiye who read and criticized so...