From complex structure elucidation to biomolecular interactions - this applicationoriented textbook covers both theory and practice of modern NMR applications.Part one sets the stage with a general description of NMR introducing important parameters such as the chemical shift and scalar or dipolar couplings. Part two describes the theory behind NMR, providing a profound understanding of the involved spin physics, deliberately kept shorter than in other NMR textbooks, and without a r...

Addressing the widespread need for a practical guide to imaging mass spectrometry (IMS), this book presents the protocols of IMS technology. As that technology expands, research groups around the world continue its development. Pharmaceutical companies are using IMS for drug analyses to study pharmacokinetics and medical properties of drugs. Drug research and disease-related biomarker screening are experiencing greater use of this technology, with a concurrent increase in the number of res...

This invaluable and up-to-date source on instruments and applications covers everything needed to employ a technique for investigating various gases and materials, including biomaterials. It includes the latest developments in light sources, signal recovery and numerical methods.There is no other single publication that reviews the entire subject of photoacoustic infrared spectroscopy in such detail. Physicists, chemists, and spectroscopists in both academic and industrial laborator...

Protein NMR Spectroscopy, Second Edition combines a comprehensive theoretical treatment of NMR spectroscopy with an extensive exposition of the experimental techniques applicable to proteins and other biological macromolecules in solution. Beginning with simple theoretical models and experimental techniques, the book develops the complete repertoire of theoretical principles and experimental techniques necessary for understanding and implementing the most sophisticated NMR experiments. Imp...

This necessary desk reference for every practicing spectroscopist represents the first definitive book written specifically to integrate knowledge about group frequencies in infrared as well as Raman spectra. In the spirit of previous classics developed by Bellamy and others, this volume has expanded its scope and updated its coverage. In addition to detailing characteristic group frequencies of compounds from a comprehensive assortment of categories, the book includes a collection of spec...

This thesis reports on the development of the first quantum enhanced microscope and on its applications in biological microscopy. The first quantum particle-tracking microscope, described in detail here, represents a pioneering advance in quantum microscopy, which is shown to be a powerful and relevant technique for future applications in science and medicine.The microscope is used to perform the first quantum-enhanced biological measurements -- a central and long-standing goal in ...

The concept of Diffusion Tensor Imaging (DTI) is often difficult to grasp, even for Magnetic Resonance physicists. Introduction to Diffusion Tensor Imaging uses extensive illustrations (not equations) to help readers to understand how DTI works. Emphasis is placed on the interpretation of DTI images, the design of DTI experiments, and the forms of application studies. The theory of DTI is constantly evolving and so there is a need for a textbook that explains how the technique works in a w...

The series Topics in Current Chemistry presents critical reviews of the present and future trends in modern chemical research. The scope of coverage is all areas of chemical science including the interfaces with related disciplines such as biology, medicine and materials science.The goal of each thematic volume is to give the non-specialist reader, whether in academia or industry, a comprehensive insight into an area where new research is emerging which is of interest to a larger sc...

In this thesis, the author has developed a high-resolution spin-resolved photoemission spectrometer that achieves the world-best energy resolution of 8 meV. The author has designed a new, highly efficient mini Mott detector that has a large electron acceptance angle and an atomically flat gold target to enhance the efficiency of detecting scattered electrons.The author measured the electron and spin structure of Bi thin film grown on a Si(111) surface to study the Rashba effect. Un...

Provides an overview of the use of mass spectrometry (MS) for the analysis of pesticide residues and their metabolites.Presents state of the-art MS techniques for the identification of pesticides and their transformation products in food and environmentCovers important advances in MS techniques including MS instrumentation and chromatographic separations (e.g. UPLC, HILIC, comprehensive GCxGC) and applicationsIllustrates the main sample preparation techniq...

This work presents a snapshot of the state of the art of modern biomolecular crystallography, from crystallisation through structure determination and even interactive presentation on the web. Methods driving the latest automated structure determination pipelines are explained, as well as how to deal with problems such as crystal pathologies that still demand expert analysis. These methods are illustrated through their application to problems of great biological interest, such as the molec...

This book presents the various types of resonance effects on excitons, biexcitons and the local electronic centers (LEC) in solids, such as paramagnetic and paraelectric resonances on excitons, exciton acoustic resonance at intra- and interband transitions, radio-optical double resonance on excitons, hole-nuclear double resonance on localized biexcitons, ENDOR and acoustic ENDOR on LEC. The criteria for the generation of coherent photons, phonons and magnons by excitons are explained. The ...