A unique love story evolves from an encounter between two souls in the margins of the temporal and infinite worlds. While driving across country in 1983, Michael Stone has an opportunity to visit the small town of his childhood. Upon arrival, he finds himself some 40 years in the past. Unnerved in his strange new circumstance, his mutual attraction with this fascinating young woman named Virginia Shelby is his only stability. Mike gradually embraces his new life and shares a profound love ...

The second volume of The Expanding Continuum of Gender-Based Violence: Trauma-Informed Care examines the impact of violence on contemporary populations which may previously have been overlooked. In this volume, special focus is given to the intersectionality of vulnerable groups and the impact of marginalization on assessment and treatment. In an effort to bridge gaps in literature, the text addresses cultural influence and socio-political issues while advising on how to best apply the acc...

The first volume of Mental Health Issues of Child Maltreatment: Contemporary Strategies is a thorough examination of current knowledge on the way child abuse and neglect can affect a child’s mental and emotional development. In this volume interdisciplinary professionals focus on the presentation and assessment of trauma with a special focus on post-pandemic emerging trends in diagnosis. This text intends to do the following: — Define the problem of child maltreatment conceptually and nume...

The second volume of Mental Health Issues of Child Maltreatment: Contemporary Strategies offers a well-rounded and comprehensive perspective on topics related to child abuse and neglect, including a focused look at intersectional populations at risk of maltreatment and how best to provide trauma-informed care. This text intends to do the following: —Define the problem of child maltreatment conceptually and numerically, using statistics that describe the state of maltreatment and the charac...

The first volume of The Expanding Continuum of Gender-Based Violence: Trauma-Informed Care is a thorough examination of current knowledge on the way gender impacts both group and individual risk of violence. In this volume, interdisciplinary professionals focus on the presentation and assessment of trauma with a special focus on trauma-informed approaches. Special emphasis is placed on inclusive language recommendations in order to guide clinicians and care providers in current best practi...

Takahata Isao (1935–2018), often referred to as the “Second Pillar” of the renowned Studio Ghibli, is one of the most esteemed animation directors in the history of the form. He is also the first, and thus far the only, anime director to have a solo exhibition at the prestigious National Museum of Modern Art in Tokyo and was widely recognized for his advocacy of environmental and pacifist causes. Takahata’s distinctive vision and range and diverse contributions in both television and film ...

The End of Alzheimer's: The Brain and Beyond, Second Edition is the first comprehensive overview on the molecular basis of Alzheimer's outside of the brain, merging the most recent findings within the field into a single book. It aims to educate the reader on the many overlooked aspects of Alzheimer's disease that occur outside the brain. This book uniquely provides step-by-step, peer-reviewed evidence that the current research model may be misguided and that a new and emerging model is mo...

Growing Up: Pastoral Nurture for the Later Years is a sensitive volume devoted to helping older adults retain their status as meaningful members of their congregations and communities. In an honest approach, based on the foundations that old age is supposed to happen, the future belongs to the old, and vocation for people of faith is lifelong, Thomas Robb provides personal and Biblical perspectives, as well as research from over 20 years as a pastor, on the life process and the feelings, w...

The Immunological Synapse - Part C, Volume 193 in the Methods in Cell Biology series provides state-of-the-art and detailed methods for the study of the T cell, natural killer (NK) cell and B cell immunological synapses. Topics covered in this third volume include tau-STED microscopy for 3D-quantitative colocalization of lytic granule markers, image processing approaches for 3D-analysis of markers and for microtubule remodeling quantification at the immunological synapse, flow cytometry to...

The Immunological Synapse - Part B, Volume 178 in the Methods in Cell Biology series provides state-of-the-art methods for the study of the immunological synapse. This first volume covers various aspects on T cell and natural killer (NK) cell synapses, including imaging polarized granule release using TIRF microscopy, analysis of actin reorganization and centrosome polarization, redirected degranulation, live cell-imaging to quantify cytotoxic and chemotactic dynamics, quantification of in...

The classic adventure from the author of The Count of Monte Cristo and The Man in the Iron Mask.In this swashbuckling epic, d’Artagnan, not yet twenty, sets off for Paris in hopes of joining the Musketeers, that legion of heroes highly favored by King Louis XIII and feared by evil Cardinal Richelieu. By fighting alongside Athos, Porthos, and Aramis as they battle their enemies, d’Artagnan proves he has the heart of a Musketeer and earns himself a ...

The Immunological Synapse, Part A, Volume 173 in the Methods in Cell Biology series provides state-of-the-art methods for the study of the immunological synapse. Sections cover Imaging polarized granule release at the cytotoxic T cell immunological synapse using TIRF microscopy: control by polarity regulators, Analysis of centrosomal area actin reorganization and centrosome polarization upon lymphocyte activation at the immunological synapse, P815-based redirected degranulation assay to st...