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Nitroazoles: Synthesis, Structure and Applications

af Lyudmila Larina, Valentin Lopyrev ...

Serier serie Chemistry and Material Science (R0)
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Steroid Analysis

Redigeret af Hugh L. J. Makin, D.B. Gower ...

Serier serie Chemistry and Material Science (R0)
The second edition of this book has drawn heavily on the first edition but a huge amount of research on steroid analysis has been published over the last 15 years. As a result, the Editors decided to let the first edition of this book stand on its own and direct readers interested in pre-1995 steroid analysis to it, simply because the post-1995 research can on its own fill the second edition. We ... Læs mere

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The second edition of this book has drawn heavily on the first edition but a huge amount of research on steroid analysis has been published over the last 15 years. As a result, the Editors decided to let the first edition of this book stand on its own and direct readers interested in pre-1995 steroid analysis to it, simply because the post-1995 research can on its own fill the second edition. We
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Frontiers in Clinical Drug Research - CNS and Neurological Disorders: Volume 5

af Atta-ur-Rahman ...

Frontiers in Clinical Drug Research - CNS and Neurological Disorders is a book series that brings updated reviews to readers interested in advances in the development of pharmaceutical agents for the treatment of central nervous system (CNS) and other nerve disorders. The scope of the eBook series covers a range of topics including the medicinal chemistry, pharmacology, molecular biology and ... Læs mere

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Frontiers in Clinical Drug Research - CNS and Neurological Disorders is a book series that brings updated reviews to readers interested in advances in the development of pharmaceutical agents for the treatment of central nervous system (CNS) and other nerve disorders. The scope of the eBook series covers a range of topics including the medicinal chemistry, pharmacology, molecular biology and
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Purinergic Receptors and their Modulators

Redigeret af Vittoria Colotta, Claudiu T. Supuran ...

Serier serie Chemistry and Material Science (R0)
This book overviews purinergic receptors that are playing key roles in human and pathophysiological processes. The book elaborates on how selective P1 and P2 modulators have been developed as therapeutics for a variety of diseases. It also provides an overview of current perspectives in the design of purinergic receptor modulators and future challenges such as the availability of selective ligands ... Læs mere

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This book overviews purinergic receptors that are playing key roles in human and pathophysiological processes. The book elaborates on how selective P1 and P2 modulators have been developed as therapeutics for a variety of diseases. It also provides an overview of current perspectives in the design of purinergic receptor modulators and future challenges such as the availability of selective ligands
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Solving a 3D Structural Puzzle

af Casper Rønn Hoeck ...

Serier serie Chemistry and Material Science (R0)
This book explores how nuclear magnetic resonance (NMR) spectroscopy may be used for spatial structural elucidation of novel compounds from fungal and synthetic sources. Readers will discover the exciting world of NOE (nuclear Overhauser effect), RDC (residual dipolar coupling) and J-coupling constants, both short- and long range. With emphasis on obtaining structural knowledge from these NMR ... Læs mere

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Advances in Nucleic Acid Therapeutics

Redigeret af Sudhir Agrawal, Michael J Gait ...

Serier Bog 68 - Drug Discovery Series
The sequencing of the human genome and subsequent elucidation of the molecular pathways that are important in the pathology of disease have provided unprecedented opportunities for the development of new therapeutics. Nucleic acid-based drugs have emerged in recent years to yield extremely promising candidates for drug therapy to a wide range of diseases. Advances in Nucleic Acid Therapeutics is a ... Læs mere

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The sequencing of the human genome and subsequent elucidation of the molecular pathways that are important in the pathology of disease have provided unprecedented opportunities for the development of new therapeutics. Nucleic acid-based drugs have emerged in recent years to yield extremely promising candidates for drug therapy to a wide range of diseases. Advances in Nucleic Acid Therapeutics is a
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Progress in the Chemistry of Organic Natural Products 116

Redigeret af A. Douglas Kinghorn, Heinz Falk, Simon Gibbons, Yoshinori Asakawa, Ji-Kai Liu, Verena M. Dirsch ...

Serier serie Chemistry and Material Science (R0)
This volume describes several highly diverse subjects: Chapter 1 explores marine biodiscovery of the North-eastern Atlantic off the coast of Ireland as a model for best practice in research. The second chapter investigates Brazilian Chemical Ecology and examples of insect-plant communication studies that are mediated by natural products demonstrate the beautiful interconnectedness of species in a ... Læs mere

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Solving Chemistry

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Chemistry as a discipline is arguably now complete – all the major problems have been solved and there are no more great discoveries to be made. In his engaging new book, Bernie Bulkin explores the research that led to the solution of all the major problems of the discipline that existed in the early 1950s. He discusses the progress of both theory and experiment, and shows, by some anecdotal data, ... Læs mere

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Infectious Diseases and Nanomedicine II

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The book addresses the interdisciplinary scientific approach for the systemic understanding of connections between major human diseases and their treatment regime by applying the tools and techniques of nanotechnology. It also highlights the interdisciplinary collaborative researches for innovation in Biomedical Sciences. The book is a second volume which presents collection of best papers ... Læs mere

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Development of Novel Hydrogen-Bond Donor Catalysts

af Tsubasa Inokuma ...

Serier serie Chemistry and Material Science (R0)
This work describes novel, effective hydrogen-bond (HB) donor catalysts based on a known bifunctional tertiary amine-thiourea, a privileged structure, which has been proven to be one of the most widely used organocatalysts. These HB donor catalysts derived from quinazoline and benzothiadiazine were initially synthesized as novel HB donors with their HB-donating abilities being measured by ... Læs mere

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This work describes novel, effective hydrogen-bond (HB) donor catalysts based on a known bifunctional tertiary amine-thiourea, a privileged structure, which has been proven to be one of the most widely used organocatalysts. These HB donor catalysts derived from quinazoline and benzothiadiazine were initially synthesized as novel HB donors with their HB-donating abilities being measured by
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Satureja: Ethnomedicine, Phytochemical Diversity and Pharmacological Activities

af Soodabeh Saeidnia, Ahmad Reza Gohari, Azadeh Manayi, Mahdieh Kourepaz-Mahmoodabadi ...

Serier serie Biomedical and Life Sciences (R0)
This book provides a comprehensive review of the literature available on satureja covering the ethnomedicine, micromorphology, the main secondary metabolites in its various species, as well it’s important biological and pharmacological activities and the underlying mechanism of action for some of its medicinal properties. There is also discussion of the pharmacological evidence for the various ... Læs mere

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Frontiers in Drug Design and Discovery: Volume 12

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Serier Bog 12 - Frontiers in Drug Design and Discovery
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Aromatic Hydroxyketones: Preparation & Physical Properties

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Bioanalysis of Pharmaceuticals

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Bioanalysis of Pharmaceuticals: Sample Preparation, Separation Techniques and Mass Spectrometry is the first student textbook on the separation science and mass spectrometry of pharmaceuticals present in biological fluids with an educational presentation of the principles, concepts and applications. It discusses the chemical structures and properties of low- and high-molecular drug substances; the ... Læs mere

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Therapeutic Rhodium Complexes

af Afzal Hussain, Mohamed F. Alajmi, Mushtaq Ahmad Lone, Waseem A. Wani ...

Serier serie Chemistry and Material Science (R0)
This book describes the emergence and recent advances in the design and development of rhodium complexes as therapeutic agents. Different classes of anticancer rhodium complexes with particular emphasis on ligands containing nitrogen-oxygen donor atoms are presented. Anticancer rhodium complexes of N-heterocyclic carbenes are described, while half-sandwich, heterobimetallic, and multinuclear ... Læs mere

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This book describes the emergence and recent advances in the design and development of rhodium complexes as therapeutic agents. Different classes of anticancer rhodium complexes with particular emphasis on ligands containing nitrogen-oxygen donor atoms are presented. Anticancer rhodium complexes of N-heterocyclic carbenes are described, while half-sandwich, heterobimetallic, and multinuclear
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Pharmacokinetics and Pharmacodynamics of Nanoparticulate Drug Delivery Systems

Redigeret af Jayvadan K. Patel, Yashwant V. Pathak ...

Serier serie Biomedical and Life Sciences (R0)
A reference is needed that addresses the recent progress in aspects of PK/PD methods and developments of nanoparticles for novel drug delivery systems. No other consolidated published reference discusses the PK/PD study of nanoparticle drug delivery systems. This book discusses the advantages of nanoparticle drug delivery systems (NPDDS) in enhancing the pharmacokinetics of many drugs that are not ... Læs mere

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A reference is needed that addresses the recent progress in aspects of PK/PD methods and developments of nanoparticles for novel drug delivery systems. No other consolidated published reference discusses the PK/PD study of nanoparticle drug delivery systems. This book discusses the advantages of nanoparticle drug delivery systems (NPDDS) in enhancing the pharmacokinetics of many drugs that are not
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Frontiers in Clinical Drug Research: Hematology Volume: 5

af Atta ur-Rahman ...

Serier Bog 5 - Frontiers in Clinical Drug Research: Hematology
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af Atta-ur-Rahman ...

Serier Bog 8 - Frontiers in Clinical Drug Research: Anti-Infectives
Frontiers in Clinical Drug Research – Anti infectives is a book series that brings updated reviews to readers interested in learning about advances in the development of pharmaceutical agents for the treatment of infectious diseases. The scope of the book series covers a range of topics including the chemistry, pharmacology, molecular biology and biochemistry of natural and synthetic drugs ... Læs mere

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Lead-Seeking Approaches

Redigeret af Matthew M. Hayward ...

Serier serie Chemistry and Material Science (R0)
High quality leads provide the foundation for the discovery of successful clinical development candidates, and therefore the identi?cation of leads is an essential part of drug discovery. The process for the identi?cation of leads generally starts with the screening of a compound collection, either an HTS of a relatively large compound collection (hundreds of thousands to one million plus ... Læs mere

1.307,67 kr.

High quality leads provide the foundation for the discovery of successful clinical development candidates, and therefore the identi?cation of leads is an essential part of drug discovery. The process for the identi?cation of leads generally starts with the screening of a compound collection, either an HTS of a relatively large compound collection (hundreds of thousands to one million plus
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Drug Development Supported by Informatics

Redigeret af Hiroko Satoh, Kimito Funatsu, Hiroshi Yamamoto ...

Serier serie Medicine (R0)
This book describes the state-of-the-art of chemoinformatics, bioinformatics, materials informatics and measurement/metrology informatics to develop drugs with desired activity or physicochemical properties and to optimize the functionality, efficacy, safety and quality of the compounds for drugs. Recently, "AI drug discovery", drug discovery research utilizing artificial intelligence technology ... Læs mere

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This book describes the state-of-the-art of chemoinformatics, bioinformatics, materials informatics and measurement/metrology informatics to develop drugs with desired activity or physicochemical properties and to optimize the functionality, efficacy, safety and quality of the compounds for drugs. Recently, "AI drug discovery", drug discovery research utilizing artificial intelligence technology
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Principles of Pharmacology

af Jahangir Moini ...

Principles of Pharmacology reviews the fundamentals of pharmacology with a focus on the various body systems. Drug classifications, names, sources, and development serve as essential foundations. Furthermore, this volume uniquely discusses that understanding pharmacokinetics, pharmacodynamics, pharmacogenomics, and drug toxicity is crucial before addressing medications, clinical indications, ... Læs mere

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Principles of Pharmacology reviews the fundamentals of pharmacology with a focus on the various body systems. Drug classifications, names, sources, and development serve as essential foundations. Furthermore, this volume uniquely discusses that understanding pharmacokinetics, pharmacodynamics, pharmacogenomics, and drug toxicity is crucial before addressing medications, clinical indications,
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Cutting-Edge Organic Synthesis and Chemical Biology of Bioactive Molecules

The Shape of Organic Synthesis to Come

Redigeret af Yuichi Kobayashi ...

Serier serie Chemistry and Material Science (R0)
This book describes cutting-edge organic syntheses of biologically active compounds, isolation of pharmaceutically promising compounds from microorganisms, drug design, and progress on chemical biology. Synthetic strategy and tactics are summarized for super-carbon chain compounds, antitumor polycycles, aryl C-glycoside, antimycins, duocarmycins, cannabinoids, and other compounds. Special chapters ... Læs mere

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This book describes cutting-edge organic syntheses of biologically active compounds, isolation of pharmaceutically promising compounds from microorganisms, drug design, and progress on chemical biology. Synthetic strategy and tactics are summarized for super-carbon chain compounds, antitumor polycycles, aryl C-glycoside, antimycins, duocarmycins, cannabinoids, and other compounds. Special chapters
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Nucleic Acid Drugs

Redigeret af Akira Murakami ...

Serier serie Chemistry and Material Science (R0)
New Antisense Strategies: Chemical Synthesis of RNA Oligomers, by Junichi Yano und Gerald E. Smyth Development and Modification of Decoy Oligodeoxynucleotides for Clinical Application, by Mariana Kiomy Osako, Hironori Nakagami und Ryuichi Morishita Modulation of Endosomal Toll-Like Receptor-Mediated Immune Responses by Synthetic Oligonucleotides, by Ekambar R. Kandimalla und Sudhir Agrawal ... Læs mere

1.868,14 kr.

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Frontiers in Clinical Drug Research - CNS and Neurological Disorders: Volume 6

af Atta-ur-Rahman ...

Frontiers in Clinical Drug Research - CNS and Neurological Disorders is a book series that brings updated reviews to readers interested in advances in the development of pharmaceutical agents for the treatment of central nervous system (CNS) and other nerve disorders. The scope of the book series covers a range of topics including the medicinal chemistry, pharmacology, molecular biology and ... Læs mere

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Frontiers in Clinical Drug Research - CNS and Neurological Disorders is a book series that brings updated reviews to readers interested in advances in the development of pharmaceutical agents for the treatment of central nervous system (CNS) and other nerve disorders. The scope of the book series covers a range of topics including the medicinal chemistry, pharmacology, molecular biology and
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Klinisk e-bøger

Nitroazoles: Synthesis, Structure and Applications

Steroid Analysis

Frontiers in Clinical Drug Research - CNS and Neurological Disorders: Volume 5

Purinergic Receptors and their Modulators

Solving a 3D Structural Puzzle

Advances in Nucleic Acid Therapeutics

Progress in the Chemistry of Organic Natural Products 116

Solving Chemistry

Infectious Diseases and Nanomedicine II

Development of Novel Hydrogen-Bond Donor Catalysts

Satureja: Ethnomedicine, Phytochemical Diversity and Pharmacological Activities

Frontiers in Drug Design and Discovery: Volume 12

Aromatic Hydroxyketones: Preparation & Physical Properties

Bioanalysis of Pharmaceuticals

Therapeutic Rhodium Complexes

Pharmacokinetics and Pharmacodynamics of Nanoparticulate Drug Delivery Systems

Frontiers in Clinical Drug Research: Hematology Volume: 5

Frontiers in Clinical Drug Research: Anti-Infectives Volume: 8

Lead-Seeking Approaches

Drug Development Supported by Informatics

Principles of Pharmacology

Cutting-Edge Organic Synthesis and Chemical Biology of Bioactive Molecules

Nucleic Acid Drugs

Frontiers in Clinical Drug Research - CNS and Neurological Disorders: Volume 6