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  • T. cruzi Infection

    Methods and Protocols

    Serier serie Springer Protocols
    This fully updated volume explores experimental methods to assess the complex interactions between Trypanosoma cruzi and its host and to study different aspects of T. cruzi and Chagas disease. The techniques presented, which touch on areas ofbioinformatics, biochemistry, genetics, and cell biology research, have been recently developed or adapted to the T. cruzi system by leading experts in the ... Læs mere

    1.867,83 kr.

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    Methods and Protocols

    Redigeret af Sweta Rani, Lukasz Skalniak ...
    Serier serie Springer Protocols
    This open access volume describes the computational and experimental models that help researchers understand the responses of the immune system in cancer and test experimental immune-oncology approaches. The chapters in this book cover methods such as profile polarization in macrophages using ELISA; immune checkpoint inhibitors; interactions of PD-1/PD-L1 and T cells; immunocompetent preclinical ... Læs mere

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  • Tertiary Lymphoid Structures

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    Redigeret af Marie-Caroline Dieu-Nosjean ...
    Serier serie Springer Protocols
    This second edition details new and updated chapters on technologies related to tertiary lymphoid structures( TLS). Chapters guide readers through TLS in cancers, different stages of TLS development, immune function of TLS, molecular, cellular, and imaging methods, and preclinical methods to uncover the function of cells composing TLS in inflammatory situations in humans. Written in the highly ... Læs mere

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  • Neuromuscular Assessments of Form and Function

    Serier serie Springer Protocols
    This volume looks at the latest methods used to study imaging techniques, metabolic tracing, and deep muscle phenotyping. The chapters in this book cover topics such as imaging skeletal muscle mass using MRI, dual-energy x-ray absorptiometry, CT, and ultrasound; measures of neuromuscular function such as power/strength/force; microscopy and immunohistochemistry; and ex vivo fibre function and ... Læs mere

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  • Neural Stem Cells

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    This detailed volume explores techniques for the study of neurogenic niches and neural lineage progression, specifically addressing major methodological challenges in studying neural stem cells (NSCs) and related cell populations, such as astrocytes, oligodendrocytes, and neurons. The chapters are organized to offer a comprehensive technical foundation, focusing on isolation and identification, ... Læs mere

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  • Cancer Immunosurveillance

    Methods and Protocols

    Serier serie Springer Protocols
    This new edition explores the innovation and improvement of experimental techniques harnessed to dissect the complex relationship between cancer cells and the immune system of the host. Beginning with spectral and multicolor flow cytometric methods to characterize the immune contexture of different forms of metastases, the book continues with functional assays to study the activation status of ... Læs mere

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  • Yellow Fever Virus

    Methods and Protocols

    Redigeret af Alice Gomes Fernandes ...
    Serier serie Springer Protocols
    This volume covers a range of fundamental and advanced techniques and methods used by researchers to study the control of yellow fever. The chapters in this book cover a broad range of topics including epidemiological studies that track the spread of disease and sophisticated laboratory techniques that investigate the disease’s pathogenesis. Written in the highly successful Methods in Molecular ... Læs mere

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    Redigeret af Giovanni Bertoni, Silvia Ferrara ...
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    This book aims to provide methods, protocols, and discussion topics for those who wish to examine in depth the molecular mechanisms of adaptation and versality of bacteria and would like to envisage their evolution responses in the fast changing Antropocene.Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists ... Læs mere

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  • Teratogenicity Testing

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    This fully updated volume collects laboratory techniques and tests to assess the risks to embryo-fetal development from drug exposure during early developmental stages. Beginning with a section detailing basic principles of teratogenicity, the book continues with application of in vitro models for teratogenic screening to predict toxicity in embryonic animals and humans, as well as a variety of ... Læs mere

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    This second edition volume expands on the previous edition with new methods and refinements ranging from tissue clearing and three-dimensional imaging, to explant culture systems, lineage tracing, high-resolution transcriptomics, metabolism, and chromatin structure analysis. The chapters in this book are organized by molecular depth, progressing from foundational methods to approaches that probe ... Læs mere

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    This detailed volume presents cutting-edge approaches to study infection, immunity, and intervention strategies against intracellular pathogens. The book explores areas such as how intracellular pathogens infect and survive inside the phagocytes, immunopathological features of infection, evasion of host-induced immune responses, cellular crosstalk in the presence of intracellular pathogens, host ... Læs mere

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