The 1973 WHO classification of bladder tumours anticipated a probable need for eventual revision of the criteria for diagnosing papillary and flat bladder neoplasia. A workshop sponsored by the WHO consisting of pathologists, urologists, cytologists, oncologists and basic scientists interested in bladder tumours addressed this subject, and after a follow- -up meeting sponsored by the International Society of Urological Pathology, the classification and terminology used in this text were ag...

This book covers all the practical issues related to the interpretation of prostatic biopsies in day-to-day practice, including: biopsy sampling and processing; the diagnosis of limited cancer; differentiation of prostate cancers from benign lesions and recognition of histologic variants; the recognition and clinical significance of “atypical” diagnoses and HGPIN; the identification of recently described entities; the contemporary approach to Gleason grading; the utility of immunohistochem...

This text provides a comprehensive, state-of-the art review of this field, and will serve as a valuable resource for clinicians, surgeons and researchers with an interest in early prostate cancer. The book reviews new data about genetic markers, transperineal mapping biopsy and mpMRI, how to apply each of these technologies in patients with elevated PSA, when a prior prostate biopsy performed by the standard TRUS method is negative and in cases where low risk disease is already diagnosed, ...

This book describes a novel and proven approach to cytologically classify urinary samples for the detection of bladder cancer and lesions of the upper urinary tract. The new method is based on the collective experience of knowledgeable cytopathologists who have tested the terminology within their own laboratories for reproducibility and predictability of neoplasms of the urinary tract. Accompanying the written criteria for each diagnostic category are meticulously photographed exemplars of...

This volume provides a practical, comprehensive overview on benign and malignant disease of the adult kidney. The text addresses the topic of assessment and management of patients with surgical renal disease. Within this scope, it includes hereditary and spontaneous renal neoplasms, as well as non-neoplastic disease that manifests as a clinically relevant mass. The book is organized into chapters focusing on discrete disease entities and incorporating pathology, surgical management, oncolo...

Atlas on the Human Testis: Normal Morphology and Pathology presents histological illustrative material from paraffin and semi-thin sections of the human testis which are routinely used in the assessment of testicular morphology, allowing an early detection of carcinoma in situ and more advanced pathological changes of the testicular parenchyma. The early detection of cancer in situ is based on the careful morphological investigation of the biopsy and immunohistoc...

This book is a comprehensive guide to rare tumors and tumor-like conditions of the urinary system and male genital organs. It comprises five chapters, devoted to the kidney, bladder, prostate, testes, and penis. Each chapter begins with a brief overview of “common” tumors and tumor-like conditions and with a section on the classification of both common and rare entities. The main clinical, pathological, immunohistochemical, and molecular findings for each rare tumor or tumor-like condition...

This book presents the morphology of different non-tumoral lesions of the testis. By showing the differential diagnosis of each lesion, it offers clinicians vital support with diagnosis and treatment. The book is divided into seven main parts: genetic and developmental pathology of the testis; infertility; vascular pathology of the testis; inflammatory pathology; pathology of the rete testis and epididymis; pathology of the vaginal tunic and paratesticular structures; and a final part deal...

This volume focuses on our current understanding of the molecular underpinnings of prostate cancer and their potential application for precision medicine approaches. The emergence and applications of new technologies has allowed for a rapid expansion of our understanding of the molecular basis of prostate cancer and has revealed a remarkable genetic heterogeneity that may underlie the clinically variable behavior of the disease. The book consists of five sections which provide insight abou...

Starting in 1986, the European School of Oncology has expanded its activities in postgraduate teaching, which consisted mainly of traditional disease-orientated courses, by promoting new educational initiatives. One of these is the cloister seminars, short meetings intended for highly qualified oncologists and dealing with specific, controversial aspects of clinical practice and research. Another is the institution of permanent study groups, also called task forces, where a limited number ...