This fourth edition of Huntington's Disease presents a comprehensive summary of the current knowledge of this disease, including the major scientific and clinical advances that have occurred since publication of the third edition in 2002. Completely updated and expanded, chapters in this volume are organized in five sections: · Clinical aspects of Huntington's disease, including updated chapters on historical perspectives, neurological, neuropsychiatric, and neuropsychological aspects, and...

Malocclusion (crooked teeth) is an ever-increasing modern day epidemic affecting millions of people all over the world. It is caused by poor facial bone growth, which results in a mouth that is simply just too small to accommodate all 32 adult teeth. For the past 200 or so years, it has almost become expected that most people will not have sufficient space for their third molars (wisdom teeth).In fact, most modern humans seldom have enough space to accommodate 28 teeth in perfect a...

Tough Test Questions? Missed Lectures? Not Enough Time?Fortunately for you, there's Schaum's.More than 40 million students have trusted Schaum's to help them succeed in the classroom and on exams. Schaum's is the key to faster learning and higher grades in every subject. Each Outline presents all the essential course information in an easy-to-follow, topic-by-topic format. You also get hundreds of examples, solved problems, and practice exercises to test yo...

There’s no easier, faster, or more practical way to learn the really tough subjectsGenetics Demystified offers an up-to-date, highly readable explanation of the basic principles of genetics, covering key topics such as human genetics, DNA, heredity, mutations, traits, chromosomes, and much more. This self-teaching guide comes complete with key points, background information, quizzes at the end of each chapter, and even a final exam. Simple enough for begin...

We all want to be healthy and live well so take charge of your health by learning the connection between our evolutionary past and our future well-being with this practical guide to personalized health and nutrition—from distinguished physician Dr. Sharad Paul.Recognized as one of the best in his field, surgeon, academic, and philanthropist Dr. Sharad Paul brings together everyday health with evolutionary biology and shows how it shapes who we are and what our bodi...

Nowadays, it is widely accepted that there is no single influence (be it nature or nurture) on cognitive development. Cognitive abilities emerge as a result of interactions between gene expression, cortical and subcortical brain networks, and environmental influences. In recent years, our study of neurodevelopmental disorders has provided much valuable information on how genes, brain development, behaviour, and environment interact to influence development from infancy to adulthood. This i...

What causes a child to grow up gay or straight? Neuroscientist Simon LeVay summarizes a wealth of scientific evidence that points to one inescapable conclusion: Sexual orientation results primarily from an interaction between genes, sex hormones, and the cells of the developing body and brain. LeVay takes the reader on a whirlwind tour of laboratories that specialize in genetics, endocrinology, neuroscience, cognitive psychology, evolutionary psychology, and family demographics. He describ...

This unique textbook provides a clear and concise overview of the key principles of the complex field of phylogenomics, with a particular focus on sequencing technologies that are crucial to studying and understanding interrelations in evolutionary genomics. It includes chapters dedicated to the analysis of nucleotide sequences using assembling and alignment methods and also discusses the main strategies for phylogenetic studies, systematic errors and their correction. This highly readable...

This volume focuses on the roles of long non-coding RNAs (lncRNAs) in contexts ranging from human cancers to cardiovascular disease and ageing. The role of lncRNAs in X-inactivation and those lncRNAs derived from pseudogenes, past retroelements integrated within the human genome, as well as the role these pseudogene-derived lncRNAs play in cancer development are discussed in detail. Further, the book examines the function of lncRNAs in diseases such as diabetes, in smooth muscle formation,...

From a review of an earlier volume: 'Both the experimental and the human aspects of teratology are presented in this comprehensive text by a stellar group of internationally recognized scientists and clinicians....A valuable resource for those concerned with experimental teratology and risk assessment and those requiring general information about the causes of birth defects. The treatment of these issues is sophisticated, succinct, and logical.'-American Scientist

The manner in which genetic research associated with addiction is conducted, interpreted and translated into clinical practice and policy initiatives raises important social, ethical and legal issues. Genetic Research on Addiction fulfils two key aims; the first is to identify the ethical issues and requirements arising when carrying out genetically-based addiction research, and the second is to explore the ethical, legal and public policy implications of interpreting, translating and appl...

Nuclear Architecture and Dynamics provides a definitive resource for (bio)physicists and molecular and cellular biologists whose research involves an understanding of the organization of the genome and the mechanisms of its proper reading, maintenance, and replication by the cell. This book brings together the biochemical and physical characteristics of genome organization, providing a relevant framework in which to interpret the control of gene expression and cell differentiation. It incl...