This book provides an introduction to investment appraisal and presents a range of methods and models, some of which are not widely known, or at least not well covered by other textbooks. Each approach is thoroughly described, evaluated and illustrated using examples, with its assumptions and limitations analyzed in terms of their implications for investment decision-making practice. Investment decisions are of vital importance to all companies. Getting these decisions right is crucial but...

The overall topic of the volume, Mathematics for Computation (M4C), is mathematics taking crucially into account the aspect of computation, investigating the interaction of mathematics with computation, bridging the gap between mathematics and computation wherever desirable and possible, and otherwise explaining why not.Recently, abstract mathematics has proved to have more computational content than ever expected. Indeed, the axiomatic method, originally intended to do away with c...

This book is for graduate students and researchers, introducing modern foundational research in mathematics, computer science, and philosophy from an interdisciplinary point of view. Its scope includes proof theory, constructive mathematics and type theory, univalent mathematics and point-free approaches to topology, extraction of certified programs from proofs, automated proofs in the automotive industry, as well as the philosophical and historical background of proof theory. By filling t...

This textbook presents concepts and applications of Management Accounting, one of the main approaches used by management to support future organisational performance. It covers methods and instruments of management and cost accounting, cost management, and management control and is based on the German textbook "Interne Unternehmensrechnung" by Ralf Ewert and Alfred Wagenhofer (Springer).The authors describe the managerial uses of accounting information, both for decision-making and...

This book has developed over the past fifteen years from a modern course on stochastic chemical kinetics for graduate students in physics, chemistry and biology. The first part presents a systematic collection of the mathematical background material needed to understand probability, statistics, and stochastic processes as a prerequisite for the increasingly challenging practical applications in chemistry and the life sciences examined in the second part.Recent advances in the devel...

Transfer prices are of dominant importance in company practice and a decentralised organisation, e.g. a profit centre-organisation, is most-widely used. This textbook takes an innovative controversial approach by looking at functions of transfer prices and how different types of transfer prices can fulfil them. Suggestions common in other textbooks will be picked up and it will be shown why they do not contribute to solve the problems companies face. With support of numerous examples and e...

This book unifies general concepts of plant and animal virus evolution and covers a broad range of topics related to theoretical and experimental aspects of virus population dynamics and viral fitness.Timely topics such as viral mechanisms to cope with antiviral agents, the adaptability of the virus to new hosts, emergence of new viral phenotypes, and the connections between short- and long-term virus evolution are included.By comparing plant and animal viruses, universal me...

This volume brings together recent developments in quasispecies theory extended to variable environments and practical applications in elucidating viral dynamics and treatment designs. In particular, the existence of an error threshold in rugged fitness landscapes has opened the way to a new antiviral strategy termed lethal mutagenesis, which is now under intensive theoretical, experimental and clinical investigation. As such the book explains how an understanding of quasispecies dynamics ...

Looking for a head start in your undergraduate degree in mathematics? Maybe you've already started your degree and feel bewildered by the subject you previously loved? Don't panic! This friendly companion will ease your transition to real mathematical thinking. Working through the book you will develop an arsenal of techniques to help you unlock the meaning of definitions, theorems and proofs, solve problems, and write mathematics effectively. All the major methods of proof - direct method...

The 2e of Molecular Diagnostics, the only book dealing with diagnosis on a molecular level, discusses current molecular biological techniques used to identify the underlying molecular defects in inherited disease. The book delves further into the principle and brief description of the technique, followed by examples from the authors' own expertise. Contributors to the 2e are well-known experts in their field, and derive from a variety of disciplines, to ensure breadth and depth of coverage...

New advances in proteomics, driven largely by developments in mass spectrometry, continue to reveal the complexity and diversity of pathogenic mechanisms among microbes that underpin infectious diseases. Therefore a new era in medical microbiology is demanding a rapid transition from current procedures to high throughput analytical systems for the diagnosis of microbial pathogens.This book covers the broad microbiological applications of proteomics and mass spectrometry. It is divi...

At the heart of this short introduction to category theory is the idea of a universal property, important throughout mathematics. After an introductory chapter giving the basic definitions, separate chapters explain three ways of expressing universal properties: via adjoint functors, representable functors, and limits. A final chapter ties all three together. The book is suitable for use in courses or for independent study. Assuming relatively little mathematical background, it is ideal fo...