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Springer Protocols Bogserier

1 - 12 af 12 resultater
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  • Poly(ADP-Ribose) Polymerase

    Methods and Protocols

    Redigeret af Alexei V. Tulin ...
    Serier serie Springer Protocols
    This detailed volume explores poly(ADP-ribose) polymerases (PARPs) in the biology of eukaryotes and their relevance to human health. Beginning with a section on the detection and quantification of poly(ADP-ribose) polymer (pADPr), the book continues by delving into the identification of protein targets, functional analysis, the poly(ADP-ribosyl)ating pathway in chromatin and genes expression, as ... Læs mere

    1.260,86 kr.

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  • The AGT Cytogenetics Laboratory Manual

    Redigeret af Marilyn S. Arsham, Margaret J. Barch, Helen J. Lawce ...
    Cytogenetics is the study of chromosome morphology, structure, pathology, function, and behavior. The field has evolved to embrace molecular cytogenetic changes, now termed cytogenomics.Cytogeneticists utilize an assortment of procedures to investigate the full complement of chromosomes and/or a targeted region within a specific chromosome in metaphase or interphase. Tools include routine analysis ... Læs mere

    1.471,24 kr.

  • Antibody Engineering Volume 1

    Redigeret af Roland E. Kontermann, Stefan Dübel ...
    Serier serie Springer Protocols
    Antibodies are indispensable tools for research, diagnosis, and therapy. Recombinant approaches allow the modification and improvement of nearly all antibody properties, such as affinity, valency, specificity, stability, serum half-life, effector functions, and immunogenicity. "Antibody Engineering" provides a comprehensive toolbox covering the well-established basics but also many exciting new ... Læs mere

    3.166,13 kr.

  • In Vitro Bioassay Techniques for Anticancer Drug Discovery and Development

    af Dhanya Sunil, Raghu Chandrashekhar H, Pooja Kamath ...
    This comprehensive and useful handbook represents a definitive up-to-date compendium of key in vitro bioassay methods that are employed to quantify and validate the anticancer activity of a drug candidate before it makes its way in to animal or clinical trials.In Vitro Bioassay Techniques for Anticancer Drug Discovery and Development covers the screening and evaluation of potential drug candidates ... Læs mere

    439,78 kr.

  • Drosophila

    Methods and Protocols

    Redigeret af Christian Dahmann ...
    Serier serie Springer Protocols
    This third edition expands on the previous editions by providing updated protocols and current methods that cover recent breakthroughs in Drosophila research. Chapters guide readers through FlyBase, versatile gene expression systems, analysis of microRNA function, single-cell transcriptome data and metabolism, recent applications of CRISPR for precise genome editing, transcriptional activation and ... Læs mere

    1.021,24 kr.

  • Heterologous Expression of Membrane Proteins

    Methods and Protocols

    Redigeret af Isabelle Mus-Veteau ...
    Serier serie Springer Protocols
    This detailed volume explores protocols for the production of membrane proteins in a panel of heterologous organisms for structural studies. Beginning with techniques using E. coli as a host for the overproduction and purification of membrane proteins, the book continues with chapters covering mammalian membrane protein production in yeast, insect cells, mammalian cells, as well as using virus ... Læs mere

    1.400,85 kr.

  • RNA-Protein Complexes and Interactions

    Methods and Protocols

    Redigeret af Ren-Jang Lin ...
    Serier serie Springer Protocols
    This second edition updates, complements, and expands upon the first edition by providing a collection of cutting-edge techniques developed or refined in the past few years along with tried-and-true methods. Chapters explore the isolation and characterization of RNA-protein complexes, the analysis and measurement of RNA-protein interaction, and related novel techniques and strategies. Written in ... Læs mere

    1.756,86 kr.

  • Enzyme-Mediated Ligation Methods

    Redigeret af Timo Nuijens, Marcel Schmidt ...
    Serier serie Springer Protocols
    This volume discusses different enzyme-catalyzed ligation methodologies for a variety of different chemical transformations. This book wants readers to view enzymes as a powerful tool in both academic and industrial research. Chapters in this book cover topics such as sortase A-mediated generation of site-specifically conjugated antibody-drug conjugates; omniligase-catalyzed inter- and ... Læs mere

    924,61 kr.

  • Base Excision Repair Pathway

    Methods and Protocols

    Redigeret af Kishor K. Bhakat, Tapas K. Hazra ...
    Serier serie Springer Protocols
    This detailed volume provides a comprehensive set of experimental protocols and useful strategies to examine the repair of damaged bases via the Base Excision Repair (BER) pathway in vitro and in cells. Beginning with multiple molecular and cellular techniques to examine the excision of damaged bases from double-stranded DNA or DNA wrapped in a nucleosome, the book continues with sections covering ... Læs mere

    1.309,23 kr.

  • Metabolic Reprogramming

    Methods and Protocols

    Redigeret af Salvatore Papa, Concetta Bubici ...
    Serier serie Springer Protocols
    This volume provides state-of-the-art methods and protocols from researchers in the field of metabolism. Chapters guide readers through methodologies measuring different aspects of lipid metabolism, quantifying the amino acids, mitochondrial and intracellular by-products, detect enzyme and kinase activities, detecting a variety of metabolic pathways, and intracellular networks including nucleotide ... Læs mere

    1.176,74 kr.

  • Single-Domain Antibodies

    Methods and Protocols

    Redigeret af Greg Hussack, Kevin A. Henry ...
    Serier serie Springer Protocols
    This volume covers current and emerging techniques for studying single-domain antibodies (sdAbs). Chapters guide readers through the biology and immunology of sdAbs in camelids and sharks, isolation of sdAbs, protein engineering approaches to optimize the solubility, stability, valency and antigen binding affinity of sdAbs, and specialized applications of sdAbs. Written in the format of the highly ... Læs mere

    1.681,11 kr.

  • Mitochondrial Medicine

    Volume 2: Assessing Mitochondria

    Redigeret af Volkmar Weissig, Marvin Edeas ...
    Serier serie Springer Protocols
    This second edition offers 88 chapters divided among three volumes providing the most comprehensive source of know-how in the wide-ranging field of Mitochondrial Medicine. Volume II guides readers through chapters on mitochondrial dysfunction, functional’ mitochondria, mitochondrial retrograde, mitochondrial dNTP pool quantification, mitochondrial ADP-ribosylation, blue-native gel approach, 3D ... Læs mere

    942,61 kr.