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  • Peptide Antibodies

    Methods and Protocols

    Redigeret af Gunnar Houen ...
    Serier serie Springer Protocols
    This detailed new edition explores current methods for the production and use of peptide antibodies. The book delves into various aspects of peptide synthesis and analysis, peptide-carrier conjugation, epitope and paratope prediction and identification, as well as improved assays and other uses of peptide antibodies. Written for the highly successful Methods in Molecular Biology series, chapters ... Læs mere

    1.587,91 kr.

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  • Antibody Engineering Volume 1

    Serier serie Springer Protocols
    Antibodies are indispensable tools for research, diagnosis, and therapy. Recombinant approaches allow the modification and improvement of nearly all antibody properties, such as affinity, valency, specificity, stability, serum half-life, effector functions, and immunogenicity. "Antibody Engineering" provides a comprehensive toolbox covering the well-established basics but also many exciting new ... Læs mere

    3.166,66 kr.

  • Current Trends in Monoclonal Antibody Development and Manufacturing

    Serier serie Biomedical and Life Sciences (R0)
    Monoclonal antibodies represent one of the fastest growing areas of new drug development within the pharmaceutical industry. Several blockbuster products have been approved over the past several years including Rituxan, Remicade, Avastin, Humira, and Herceptin. In addition, over 300 new drugs are currently in clinical trials. With both large, established biotechnology companies and small start-ups ... Læs mere

    1.868,14 kr.

  • Mass Spectrometry-Based Proteomics

    Redigeret af Kris Gevaert ...
    Serier serie Springer Protocols
    This detailed volume explores contemporary techniques in mass spectrometry-based proteomics. After covering overall proteome coverage and the cellular surfaceome, the book delves into proximity-induced biotinylation, abduction of protein complexes in viral-like particles, and thermal proteome profiling, as well as protocols for identifying protein N-terminal acetylation, protein processing by ... Læs mere

    1.571,37 kr.

  • Proteases and Cancer

    Methods and Protocols

    Redigeret af Salvatore Santamaria ...
    Serier serie Springer Protocols
    This volume details bioinformatics analysis, biochemical assays, recombinant protein expression and purification, methods to investigate protease activity in cell-based, organoids and in vivo systems, proteomics, transcriptomics, machine learning and novel approaches to target dysregulated protease activity in cancer. Written in the highly successful Methods in Molecular Biology series format, ... Læs mere

    1.222,11 kr.

  • Recombinant Glycoproteins

    Methods and Protocols

    Redigeret af Steven B. Bradfute ...
    Serier serie Springer Protocols
    This detailed volume explores the production and purification of glycoproteins for therapeutic use or basic research, as well as the necessary in-depth understanding of cellular and acellular systems available for these purposes, their advantages and disadvantages, and considerations for choosing the most appropriate system for the desired application. Beginning with chapters on viral-encoded ... Læs mere

    1.222,11 kr.

  • Protein Tyrosine Phosphatases

    Methods and Protocols

    Serier serie Springer Protocols
    This second edition volume expands on the previous edition with discussions on the latest advancements in protein tyrosine phosphatases (PTP) research used to investigate these essential enzymes and new inhibitors. The new techniques covered in the chapters of this book include studying enzymes in vitro, in cells, and in animal models through proteomics, genomics, and structural biology. ... Læs mere

    1.484,03 kr.

  • B-Cell Receptor Signaling

    Methods and Protocols

    Redigeret af Palash Chandra Maity ...
    Serier serie Springer Protocols
    B-lymphocytes produce antibodies, mediate humoral responses, and act as a key to the adaptive immune system of our body. The development and function of B cells are largely dependent on B cell antigen receptors (BCRs), which transmit a multitude of signals upon binding to the cognate antigen and activate the survival, proliferation, and differentiation of B cells thereof. Thus, studying the BCR ... Læs mere

    2.139,13 kr.

  • Bispecific Antibodies

    Methods and Protocols

    Redigeret af Masahiro Yasunaga ...
    Serier serie Springer Protocols
    This volume explores protocols and perspectives for the design, production, characterization, functional evaluation, and clinical translation of bispecific antibodies (BsAbs). Beginning with a variety of platforms for generating BsAbs, the book continues with sections covering protocols to evaluate T-cell-dependent bispecific antibodies, modeling and simulation approaches to support clinical ... Læs mere

    1.681,32 kr.

  • Proteoglycans

    Methods and Protocols

    Redigeret af Nikos K. Karamanos ...
    Serier serie Springer Protocols
    This volume is acomprehensive and up-to-date collection of strategies, reproducible methods, and protocols for the in-depth analysis of Proteoglycans (PGs) and their glycan part, the GAGs. Chapters are divided into three parts detailing GAGs in biological specimens, protocols for the evaluation of the in vitro and in vivo effects of PGs/GAGs, and protocols for compounds related with the metabolic ... Læs mere

    1.134,86 kr.

  • Translational Research Methods for Tauopathies

    Redigeret af Jessica S. Fortin ...
    Serier serie Springer Protocols
    This volume provides the novice to expert tau scientist with detailed protocols to establish in vitro and in vivo techniques designed for understanding the physiopathology of tau in neurodegenerative diseases. The protocols in this book were intentionally selected to provide a basis for research laboratories focusing on tau neurodegenerative drug discovery, and are organized into four cohesive ... Læs mere

    1.868,14 kr.

  • Bioconjugation Methods

    Redigeret af Alexander Deiters ...
    Serier serie Springer Protocols
    This volume presents cutting-edge chemical and molecular strategies. Chapters detail bioorthogonal cycloadditions, electrophiles, self‑labeling systems, noncanonical amino acids, site‑selective bioconjugation across proteins, nucleic acids, cells, and viral assemblies.Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective ... Læs mere

    1.868,14 kr.