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Mass Spectrometry Based Single Cell Proteomics

Redigeret af Akos Vegvari, Jaakko Teppo, Roman A. Zubarev ...

Serier serie Springer Protocols
This volume explores the latest advancements made in the field of mass spectrometry (MS) based single cell proteomics. The chapters in this book focus on technologies, methods, and biological applications and together cover the entire single cell proteomics analysis workflow, from sample collection and preparation through liquid chromatographic separation and mass spectrometric data acquisition to ... Læs mere

1.092,74 kr.

This volume explores the latest advancements made in the field of mass spectrometry (MS) based single cell proteomics. The chapters in this book focus on technologies, methods, and biological applications and together cover the entire single cell proteomics analysis workflow, from sample collection and preparation through liquid chromatographic separation and mass spectrometric data acquisition to
... Læs mere

Bioreactors

Design, Operation and Novel Applications

af Carl-Fredrik Mandenius ...

In this expert handbook both the topics and contributors are selected so as to provide an authoritative view of possible applications for this new technology. The result is an up-to-date survey of current challenges and opportunities in the design and operation of bioreactors for high-value products in the biomedical and chemical industries.Combining theory and practice, the authors explain such ... Læs mere

1.242,74 kr.

In this expert handbook both the topics and contributors are selected so as to provide an authoritative view of possible applications for this new technology. The result is an up-to-date survey of current challenges and opportunities in the design and operation of bioreactors for high-value products in the biomedical and chemical industries.Combining theory and practice, the authors explain such
... Læs mere
Applied Computer-Aided Drug Design: Models and Methods

af Igor José dos Santos Nascimento ...

Designing and developing new drugs is an expensive and time-consuming process, and there is a need to discover new tools or approaches that can optimize this process. Applied Computer-Aided Drug Design: Models and Methods compiles information about the main advances in computational tools for discovering new drugs in a simple and accessible language for academic students to early career ... Læs mere

312,49 kr.

Designing and developing new drugs is an expensive and time-consuming process, and there is a need to discover new tools or approaches that can optimize this process. Applied Computer-Aided Drug Design: Models and Methods compiles information about the main advances in computational tools for discovering new drugs in a simple and accessible language for academic students to early career
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Mass Spectrometry-Based Proteomics

Redigeret af Kris Gevaert ...

Serier serie Springer Protocols
This detailed volume explores contemporary techniques in mass spectrometry-based proteomics. After covering overall proteome coverage and the cellular surfaceome, the book delves into proximity-induced biotinylation, abduction of protein complexes in viral-like particles, and thermal proteome profiling, as well as protocols for identifying protein N-terminal acetylation, protein processing by ... Læs mere

1.414,11 kr.

This detailed volume explores contemporary techniques in mass spectrometry-based proteomics. After covering overall proteome coverage and the cellular surfaceome, the book delves into proximity-induced biotinylation, abduction of protein complexes in viral-like particles, and thermal proteome profiling, as well as protocols for identifying protein N-terminal acetylation, protein processing by
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Principles and Practices of Lyophilization in Product Development and Manufacturing

Redigeret af Feroz Jameel ...

Serier serie Biomedical and Life Sciences (R0)
The biotechnology/biopharmaceutical sector has tremendously grown which led to the invention of engineered antibodies such as Antibody Drug Conjugates (ADCs), Bispecific T cell engager ( BITES), Dual Variable Domain ( DVD), Chimeric Antigen Receptor - Modified Tcells (CART) that are currently being used as therapeutic agents for immunology and oncology disease conditions. In addition to other ... Læs mere

1.428,99 kr.

The biotechnology/biopharmaceutical sector has tremendously grown which led to the invention of engineered antibodies such as Antibody Drug Conjugates (ADCs), Bispecific T cell engager ( BITES), Dual Variable Domain ( DVD), Chimeric Antigen Receptor - Modified Tcells (CART) that are currently being used as therapeutic agents for immunology and oncology disease conditions. In addition to other
... Læs mere
Clinical Metabolomics

Methods and Protocols

Redigeret af Martin Giera, Elena Sánchez-López ...

Serier serie Springer Protocols
This second edition volume presents new and updated protocols on comprehensive compendium of clinical metabolomics protocols covering LC-MS, GC-MS, CE-MS, and NMR-based clinical metabolomics as well as bioinformatics and study design considerations. Chapters explore the core of several promising initiatives evolving around personalized health care and precision medicine. Written for the highly ... Læs mere

1.681,04 kr.

This second edition volume presents new and updated protocols on comprehensive compendium of clinical metabolomics protocols covering LC-MS, GC-MS, CE-MS, and NMR-based clinical metabolomics as well as bioinformatics and study design considerations. Chapters explore the core of several promising initiatives evolving around personalized health care and precision medicine. Written for the highly
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SH2 Domains

Functional Modules and Evolving Tools in Biology

Redigeret af Teresa Carlomagno, Maja Köhn ...

Serier serie Springer Protocols
This volume looks at the latest methods used to study and modulate the biological function and mechanisms of SH2 domains. The chapters in this book are organized into five parts. Part One presents methodology aimed at determining the structures and dynamics of SH2 domains and their complexes with phosphopeptides. Part Two discusses techniques to understand and predict interactions of SH2 domains ... Læs mere

1.414,11 kr.

This volume looks at the latest methods used to study and modulate the biological function and mechanisms of SH2 domains. The chapters in this book are organized into five parts. Part One presents methodology aimed at determining the structures and dynamics of SH2 domains and their complexes with phosphopeptides. Part Two discusses techniques to understand and predict interactions of SH2 domains
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Potassium Channels

Methods and Protocols

Redigeret af Simone Furini ...

Serier serie Springer Protocols
K+ channels regulate the passage of potassium ions across lipid membranes, influencing numerous biological functions, including homeostasis, sensory perception, and information transmission. This volume explores the widespread involvement of K+ channels in cellular processes, which makes these membrane proteins intriguing targets for both fundamental scientific inquiry and the development of ... Læs mere

1.849,24 kr.

K+ channels regulate the passage of potassium ions across lipid membranes, influencing numerous biological functions, including homeostasis, sensory perception, and information transmission. This volume explores the widespread involvement of K+ channels in cellular processes, which makes these membrane proteins intriguing targets for both fundamental scientific inquiry and the development of
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Structural Genomics and Drug Discovery

Methods and Protocols

Redigeret af Wayne F. Anderson ...

Serier serie Springer Protocols
Structural Genomics and Drug Discovery: Methods and Protocols focuses on high throughput structure determination methods and how they can be applied to lay the groundwork for structure aided drug discovery. The methods and protocols that are described can be applied in any laboratory interested in using detailed structural information to advance the initial stages of drug discovery. Written in the ... Læs mere

840,49 kr.

Structural Genomics and Drug Discovery: Methods and Protocols focuses on high throughput structure determination methods and how they can be applied to lay the groundwork for structure aided drug discovery. The methods and protocols that are described can be applied in any laboratory interested in using detailed structural information to advance the initial stages of drug discovery. Written in the
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Nucleic Acid Aptamers

Selection, Characterization, and Application

Redigeret af Günter Mayer, Marcus M. Menger ...

Serier serie Springer Protocols
This updated book reflects improvements in a variety of techniques used to study the aptamer field. Beginning with a section on selection procedures, the volume continues with methods to characterize aptamers’ interaction and structural properties by biophysical approaches, as well as a variety of applications that have been adapted to the aptamer compound class. Written for the highly successful ... Læs mere

933,87 kr.

This updated book reflects improvements in a variety of techniques used to study the aptamer field. Beginning with a section on selection procedures, the volume continues with methods to characterize aptamers’ interaction and structural properties by biophysical approaches, as well as a variety of applications that have been adapted to the aptamer compound class. Written for the highly successful
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Chemogenomics

Methods and Protocols

Redigeret af Daniel Merk, Apirat Chaikuad ...

Serier serie Springer Protocols
This volume presents both theoretical guidance and protocols on chemogenomics including chemogenomics library assembly, compound profiling, and phenotypic assays. The chapters in this book cover topics such as the assembly and use of Kinase Chemogenomics; data mining for chemogenomic compound candidates; protocols for protein family-focused assay systems to profile chemogenomic compounds; ... Læs mere

1.176,74 kr.

This volume presents both theoretical guidance and protocols on chemogenomics including chemogenomics library assembly, compound profiling, and phenotypic assays. The chapters in this book cover topics such as the assembly and use of Kinase Chemogenomics; data mining for chemogenomic compound candidates; protocols for protein family-focused assay systems to profile chemogenomic compounds;
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MicroRNA Detection and Target Identification

Methods and Protocols

Redigeret af Tamas Dalmay ...

Serier serie Springer Protocols
This updated volume reflects new and evolved techniques to study detection, profiling, and manipulation of microRNAs (miRNAs) in plants and animals. After overviews of how best to detect, identify, and validate microRNAs, the book continues by exploring state-of-the-art protocols for microRNA detection, approaches to profile the expression level of microRNAs, spatial expression analysis, describe ... Læs mere

1.021,24 kr.

This updated volume reflects new and evolved techniques to study detection, profiling, and manipulation of microRNAs (miRNAs) in plants and animals. After overviews of how best to detect, identify, and validate microRNAs, the book continues by exploring state-of-the-art protocols for microRNA detection, approaches to profile the expression level of microRNAs, spatial expression analysis, describe
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Mass Spectrometry Based Single Cell Proteomics

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Bioreactors

Applied Computer-Aided Drug Design: Models and Methods

Mass Spectrometry-Based Proteomics

Principles and Practices of Lyophilization in Product Development and Manufacturing

Clinical Metabolomics

SH2 Domains

Potassium Channels

Structural Genomics and Drug Discovery

Nucleic Acid Aptamers

Chemogenomics

MicroRNA Detection and Target Identification