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  • NMDA Receptors

    Methods and Protocols

    Serier serie Springer Protocols
    This fully updated volume explores N-Methyl-D-aspartate receptors (NMDARs), and the structure-function relations, principles, and rules that govern how NMDARs operate in brain processing under normal and pathological conditions. With chapters from leading laboratories around the world, this book examines the expression and purification of diverse NMDA receptor subtypes, gene targeting and ... Læs mere

    1.483,79 kr.

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  • Applications of Flow Cytometry in Stem Cell Research and Tissue Regeneration

    A much-needed primer on the use of laser flow cytometry for stem cell analysisLaser flow cytometry is a powerful tool for rapid analysis of cells for marker expression, cell cycle position, proliferation, and apoptosis. However, no resources specifically address the use of this methodology for the study of stem cells; this is especially important as stem cell analysis involves specialized methods ... Læs mere

    1.269,11 kr.

  • Zebrafish

    Methods and Protocols

    Serier serie Springer Protocols
    This fully updated edition introduces new tools, models, and analytic insights that position the zebrafish even more strongly as an engine of discovery for developmental and disease biology. Beginning with a section exploring detailed methods for use of zebrafish to model a variety of human diseases, the book continues by illuminating the key ongoing role of the fish model in studies of the ... Læs mere

    1.641,99 kr.

  • Physiology of Neurons

    Redigeret af Anne Feltz ...
    Thanks to tremendous technical advances in molecular biology and cellular imaging after those in electrophysiology, there is now a deep understanding of the physiology of nerve cells and their synaptic interconnections. The complexity of the brain emerges from the communication and interaction between billions of these elements. This book explores systematically and didactically the details of ... Læs mere

    1.341,12 kr.

  • Drosophila

    Methods and Protocols

    Redigeret af Christian Dahmann ...
    Serier serie Springer Protocols
    This third edition expands on the previous editions by providing updated protocols and current methods that cover recent breakthroughs in Drosophila research. Chapters guide readers through FlyBase, versatile gene expression systems, analysis of microRNA function, single-cell transcriptome data and metabolism, recent applications of CRISPR for precise genome editing, transcriptional activation and ... Læs mere

    1.021,24 kr.

  • Single Cell ‘Omics of Neuronal Cells

    Serier serie Springer Protocols
    This volume discusses the latest techniques used in the diverse fields of single cell ‘omics and covers topics such as quantifying the single cell transcriptome; isolation of cells in nanoliter volumes for single cell proteomics measurements by nano-LC-MS/MS; and single cell protein characterization by immunoblotting. A wide range of methodologies are highlighted, ranging from high-yield chemical ... Læs mere

    1.400,85 kr.

  • Optogenetics

    Light-Sensing Proteins and Their Applications in Neuroscience and Beyond

    Serier serie Biomedical and Life Sciences (R0)
    This book, now in a thoroughly revised second edition, offers a comprehensive review of the rapidly growing field of optogenetics, in which light-sensing proteins are genetically engineered into cells in order to acquire information on cellular physiology in optical form or to enable control of specific network in the brain upon activation by light. Light-sensing proteins of various living ... Læs mere

    2.345,24 kr.

  • New Technologies for Glutamate Interaction

    Neurons and Glia

    Redigeret af Maria Kukley ...
    Serier serie Springer Protocols
    This volume explores the latest technologies used to study the co-existence of neuronal and neuron-glia synapses in the brain. The chapters in this volume are organized into three parts. Part One covers recent advancements in the technical approaches for studying glutamatergic signalling between neurons. Part Two highlights approaches to study the functional role of astrocytes at neuronal synapses ... Læs mere

    1.824,31 kr.

  • Activity-Based Proteomics

    Methods and Protocols

    Redigeret af Zhipeng Tao ...
    Serier serie Springer Protocols
    This volume comprehensively covers techniques that use activity-based proteomics to investigate biological functions of proteins such as lipolytic enzymes, serine hydrolases, chitinases, and glycoside hydrolases. The chapters in this book cover a wide range of protocols and an overview on the application of activity-based proteomics profiling to study deISGylating enzymes, serine hydrolases, ... Læs mere

    2.138,77 kr.

  • Circadian Clocks

    Serier serie Springer Protocols
    This volume provides backgrounds, methods, and troubleshooting for the analysis of circadian rhythms at the molecular, cellular, and organismal levels in vertebrates and invertebrates, and also covers light input, sleep, circalunar rhythms, and seasonal rhythms. The chapters in this book discuss behavioral and biological testing, histochemistry, single-cell imaging, electrophysiology, ... Læs mere

    933,87 kr.

  • Methods in Neurodegenerative Disease Drug Discovery

    Redigeret af Diego Muñoz-Torrero ...
    Serier serie Springer Protocols
    This book explores the latest developments in the identification of biomarkers for early diagnosis of neurodegenerative diseases and methodologies for the biophysical; in vitro; cell-based; and in vivo profiling, during the early phases of drug discovery, new hits, leads, and drug candidates directed to a variety of biological targets with key pathogenic roles in neurodegenerative diseases. In the ... Læs mere

    2.325,57 kr.

  • Alternative Splicing

    Methods and Protocols

    Redigeret af Peter Scheiffele, Oriane Mauger ...
    Serier serie Springer Protocols
    This detailed volume collects commonly used and cutting-edge methods to analyze alternative splicing, a key step in gene regulation. After an introduction of the alternative splicing mechanism and its targeting for therapeutic strategies, the book continues with techniques for analyzing alternative splicing profiles in complex biological systems, visualizing and localizing alternative spliced ... Læs mere

    1.400,85 kr.